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Galkin S.A.

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences

Kornetova E.G.

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences

Lebedeva V.F.

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences

Kornetov A.N.

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences

Search for risk factors for slowed intra-atrial conduction in patients with schizophrenia

Authors:

Galkin S.A., Kornetova E.G., Lebedeva V.F., Kornetov A.N.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(11): 111‑116

DOI: 10.17116/jnevro2025125111111

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Table of contents

SEARCH FOR RISK FACTORS FOR SLOWED INTRA-ATRIAL CONDUCTION IN PATIENTS WITH SCHIZOPHRENIA
SEARCH FOR RISK FACTORS FOR SLOWED INTRA-ATRIAL CONDUCTION IN PATIENTS WITH SCHIZOPHRENIA

To cite this article:

Galkin SA, Kornetova EG, Lebedeva VF, Kornetov AN. Search for risk factors for slowed intra-atrial conduction in patients with schizophrenia. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(11):111‑116. (In Russ.)
https://doi.org/10.17116/jnevro2025125111111

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

To study the risk factors for a slowed intra-atrial conduction in patients with schizophrenia.

MATERIAL AND METHODS

One hundred twenty-two electrocardiograms of patients with schizophrenia who took antipsychotics were analyzed. The components of the metabolic syndrome, as well as anthropometric parameters, were identified as potential risk factors.

RESULTS

Slowed intra-atrial conduction (P >0.10 s) was found in 21 (17.2%) patients. Therefore, the patients were divided into two groups depending on the presence or absence of slowed intra-atrial conduction. Male sex (p=0.031), the duration of basic therapy (p<0.001), hypertriglyceridemia (p=0.043), the presence of metabolic syndrome (p=0.015), and hypersthenic body type (p<0.001) were statistically significant risk factors for slowed intra-atrial conduction in patients with schizophrenia.

CONCLUSION

If these risk factors are identified in patients with schizophrenia, continuous monitoring of the electrocardiogram and pharmacological interventions are recommended for the identified indications.

Keywords:

schizophrenia
atrial fibrillation
intra-atrial conduction
risk factors
antipsychotics
therapy
metabolic syndrome
body type

Authors:

Galkin S.A.

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences

Kornetova E.G.

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences

Lebedeva V.F.

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences

Kornetov A.N.

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences

Received:

07.06.2025

Accepted:

23.07.2025

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