The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Galkin S.A.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Science

Modern concepts of sleep disturbances associated with mental disorders

Authors:

Galkin S.A.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(6): 7‑12

DOI: 10.17116/jnevro20251250617

Read: 1629 times

Contact the author
Table of contents

MODERN CONCEPTS OF SLEEP DISTURBANCES ASSOCIATED WITH MENTAL DISORDERS
MODERN CONCEPTS OF SLEEP DISTURBANCES ASSOCIATED WITH MENTAL DISORDERS

To cite this article:

Galkin SA. Modern concepts of sleep disturbances associated with mental disorders. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(6):7‑12. (In Russ.)
https://doi.org/10.17116/jnevro20251250617

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
МСФ на ЯМ
Использование инфографики авторами научных работ
Recommended articles:
Factors influencing the achievement of remi­ssion in patients with alco­hol depe­ndence and concomitant psychological diso­rders. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(6):21-30
Mental diso­rders in mili­tary personnel at the stage of medi­cal care in a multidisciplinary mili­tary medi­cal orga­nization. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(6):37-44
Asso­ciation of cortisol levels with psychopathological features of depression and therapeutic response in female patients. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(6):45-54
The effect of inso­mnia therapy on treatment outcomes in patients with chro­nic tension headache. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(6):77-83
Vali­dation of the Snaith—Hamilton Pleasure Scale to assess anhe­donia in patients with unipolar depression In Russia. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(7):110-121
Factors supporting chro­nic inflammation in mental illness. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(8):7-15
Gender characteristics of cardiovascular diseases psychosocial risk factors asso­ciations with sleep quality in an open urban popu­lation. Russian Journal of Preventive Medi­cine. 2025;(6):67-73
Dysfunctional pelvic pain in women. Russian Journal of Pain. 2025;(2):32-37
Asso­ciation of adipokines and sleep diso­rders among the 25—44 year-old people. Russian Journal of Preventive Medi­cine. 2025;(8):41-47
Abstract:

Insomnia is a highly prevalent condition in the general population that has multiple social and health consequences. Insomnia can be both a separate clinical syndrome and a symptom of many mental disorders, thereby increasing the severity of the underlying disease and the risk of relapse. Some medications can also cause insomnia. Timely treatment of insomnia can lead to a favorable outcome (recovery) not only by alleviating the symptoms of a concomitant mental disorder, but also by preventing new episodes. Therefore, it is crucial to be aware of the association between insomnia and mental illness. This review addresses this association and provides guidelines for diagnosis and therapy.

Keywords:

insomnia
sleep disorders
mental disorders
depression
alcohol dependence
schizophrenia
anxiety disorder

Authors:

Galkin S.A.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Science

Received:

16.12.2022

Accepted:

23.12.2022

Close metadata

References:

  1. Melnikov AYu. Acute insomnia: natural course and possibilities of correction. S.S. Korsakov Journal of Neurology and Psychiatry. 2019;4-2:28-35. (In Russ.). https://doi.org/10.17116/jnevro201911904228
  2. Burchakov DI, Tardov MV. Insomnia (insomnia): causes, treatment methods and clinical situations. Consilium Medicum. 2020;2:75-82. (In Russ.).
  3. Burchakov DI, Tardov MV. Insomnia in the therapist’s practice: the role of doxylamine. Medicinskij sovet. 2020;2:45-53. (In Russ.). https://doi.org/10.21518/2079-701X-2020-2-45-53
  4. Khurshid K.A. Comorbid Insomnia and Psychiatric Disorders: An Update. Innov Clin Neurosci. 2018;3-4:28-32. 
  5. Burgart YuV, Romanova ZhV, Dushpanova AT. Insomnia as a predictor of mental disorders of mankind (literature review). Vestnik Kazahskogo nacional’nogo medicinskogo universiteta. 2021;1:92-96. (In Russ.).
  6. Fortier-Brochu E., Morin C.M. Cognitive impairment in individuals with insomnia: clinical significance and correlates. Sleep. 2014;11:1787-1798. https://doi.org/10.5665/sleep.4172
  7. Riemann D., Krone L.B., Wulff K., Nissen C. Sleep, insomnia, and depression. Neuropsychopharmacology. 2020;1:74-89.  https://doi.org/10.1038/s41386-019-0411-y
  8. Ettensohn M., Soto Y., Bassi B., Khurshid K.A. Sleep problems and disorders in patients with depression. Psychiatric Annals. 2016;7:390-395.  https://doi.org/10.3928/00485713-20160502-01
  9. Kovrov GV, Lebedev MA, Palatov SYu. et al. Sleep disorders in anxiety and anxiety-depressive disorders. breast cancer. RMZH. Medicinskoe obozrenie. 2015;10:530-534. (In Russ.).
  10. Chang P.P., Ford D.E., Mead L.A. et al. Insomnia in young men and subsequent depression. The Johns Hopkins Precursors Study. Am J Epidemiol. 1997;2:105-114.  https://doi.org/10.1093/oxfordjournals.aje.a009241
  11. Montgomery S.A., Asberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry. 1979;134:382-389.  https://doi.org/10.1192/bjp.134.4.382
  12. Ağargün M.Y., Kara H., Solmaz M. Sleep disturbances and suicidal behavior in patients with major depression. J Clin Psychiatry. 1997;6:249-251.  https://doi.org/10.4088/jcp.v58n0602
  13. Thase ME. Depression, sleep, and antidepressants. J Clin Psychiatry. 2008;4:55-65. 
  14. Franzen P.L., Buysse D.J. Sleep disturbances and depression: risk relationships for subsequent depression and therapeutic implications. Dialogues Clin Neurosci. 2008;4:473-481.  https://doi.org/10.31887/DCNS.2008.10.4/plfranzen
  15. Inada K., Enomoto M., Yamato K. et al. Effect of residual insomnia and use of hypnotics on relapse of depression: a retrospective cohort study using a health insurance claims database. J Affect Disord. 2021;281:539-546.  https://doi.org/10.1016/j.jad.2020.12.040
  16. Manber R., Edinger J.D., Gress J.L. et al. Cognitive behavioral therapy for insomnia enhances depression outcome in patients with comorbid major depressive disorder and insomnia. Sleep. 2008;4:489-495.  https://doi.org/10.1093/sleep/31.4.489
  17. Parfenova EV. Cognitive behavioral therapy for insomnia. Rossijskij nevrologicheskij zhurnal. 2019;6:14-20. (In Russ.). https://doi.org/10.30629/2658-7947-2019-24-6-14-20
  18. Khaledi-Paveh B., Maazinezhad S., Rezaie L., Khazaie H. Treatment of chronic insomnia with atypical antipsychotics: results from a follow-up study. Sleep Sci. 2021;1:27-32. 
  19. Thase M.E. Antidepressant treatment of the depressed patient with insomnia. J Clin Psychiatry. 1999;17:28-31. 
  20. Volel BA, Petelin DS, Poluektov MG. Modern ideas about insomnia in mental disorders (clinical aspects). Zhurnal nevrologii i psihiatrii im. C.C. Korsakova. 2019;4-2:63-68. (In Russ.). https://doi.org/10.17116/jnevro201911904263
  21. Yastrebova VV. Therapy of depressive disorders with insomniac disorders: possibilities of combination therapy with the use of selective hypnotics. Rossijskij psihiatricheskij zhurnal. 2011;5:72-81. (In Russ.).
  22. Kaskie R.E., Graziano B., Ferrarelli F. Schizophrenia and sleep disorders: links, risks, and management challenges. Nat Sci Sleep. 2017;9:227-239.  https://doi.org/10.2147/NSS.S121076
  23. Doneh B. Epworth Sleepiness Scale. Occup Med (Lond). 2015;6:508.  https://doi.org/10.1093/occmed/kqv042
  24. Morin C.M., Belleville G., Bélanger L., Ivers H. The Insomnia Severity Index: psychometric indicators to detect insomnia cases and evaluate treatment response. Sleep. 2011;5:601-608.  https://doi.org/10.1093/sleep/34.5.601
  25. Buysse D.J., Reynolds C.F., Monk T.H. et al. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989;2:193-213.  https://doi.org/10.1016/0165-1781(89)90047-4
  26. Carruthers S.P., Brunetti G., Rossell S.L. Sleep disturbances and cognitive impairment in schizophrenia spectrum disorders: a systematic review and narrative synthesis. Sleep Med. 2021;84:8-19.  https://doi.org/10.1016/j.sleep.2021.05.011
  27. Ashton A., Jagannath A. Disrupted Sleep and Circadian Rhythms in Schizophrenia and Their Interaction With Dopamine Signaling. Front Neurosci. 2020;14:636.  https://doi.org/10.3389/fnins.2020.00636
  28. Nelson B., Torregrossa L., Thompson A. et al. Improving treatments for psychotic disorders: beyond cognitive behaviour therapy for psychosis. Psychosis. 2021;1:78-84.  https://doi.org/10.1080/17522439.2020.1742200
  29. Myles H., Myles N., Antic N.A. et al. Obstructive sleep apnea and schizophrenia: A systematic review to inform clinical practice. Schizophr Res. 2016;1:222-225.  https://doi.org/10.1016/j.schres.2015.11.014
  30. Pleava R., Mihaicuta S., Serban C.L. et al. Long-Term Effects of Continuous Positive Airway Pressure (CPAP) Therapy on Obesity and Cardiovascular Comorbidities in Patients with Obstructive Sleep Apnea and Resistant Hypertension-An Observational Study. J Clin Med. 2020;9:2802. https://doi.org/10.3390/jcm9092802
  31. Monti J.M., Torterolo P., Pandi Perumal S.R. The effects of second generation antipsychotic drugs on sleep variables in healthy subjects and patients with schizophrenia. Sleep Med Rev. 2017;33:51-57.  https://doi.org/10.1016/j.smrv.2016.05.002
  32. Gerasimova V., Kornetova E., Kornetov A. et al. Association of separate components of the metabolic syndrome and suicidal risk in patients with schizophrenia. Eur Psychiatry. 2021;64:523-524.  https://doi.org/10.1192/j.eurpsy.2021.1398
  33. Duan C., Jenkins Z.M., Castle D. Therapeutic use of melatonin in schizophrenia: A systematic review. World J Psychiatry. 2021;8:463-476.  https://doi.org/10.5498/wjp.v11.i8.463
  34. Overbeek T., van Diest R., Schruers K. et al. Sleep complaints in panic disorder patients. J Nerv Ment Dis. 2005;7:488-493.  https://doi.org/10.1097/01.nmd.0000168233.43673.0e
  35. Potvin O., Lorrain D., Belleville G. et al. Subjective sleep characteristics associated with anxiety and depression in older adults: a population-based study. Int J Geriatr Psychiatry. 2014;12:1262-1270. https://doi.org/10.1002/gps.4106
  36. Papadimitriou G.N., Linkowski P. Sleep disturbance in anxiety disorders. Int Rev Psychiatry. 2005;4:229-236.  https://doi.org/10.1080/09540260500104524
  37. Ohayon M.M., Lemoine P. Liens entre insomnie et pathologie psychiatrique dans la population générale française [A connection between insomnia and psychiatric disorders in the French general population]. Encephale. 2012;28:420-428. 
  38. Ohayon M.M. Prevalence of DSM-IV diagnostic criteria of insomnia: distinguishing insomnia related to mental disorders from sleep disorders. J Psychiatr Res. 2007;3:333-346.  https://doi.org/10.1016/s0022-3956(97)00002-2
  39. Alfano C.A., Reynolds K., Scott N. et al. Polysomnographic sleep patterns of non-depressed, non-medicated children with generalized anxiety disorder. J Affect Disord. 2013;1-3:379-384.  https://doi.org/10.1016/j.jad.2012.08.015
  40. Monti J.M., Monti D. Sleep disturbance in generalized anxiety disorder and its treatmen. Sleep Med Rev. 2015;3:263-276. 
  41. Grigorova OV, Akhapkin RV, Aleksandrovsky YuA. Modern concepts of pathogenetic therapy of anxiety disorders. Zhurnal nevrologii i psihiatrii im. C.C. Korsakova. 2019;10:111-120. (In Russ.). https://doi.org/10.17116/jnevro2019119101111
  42. Stein M.A., Weiss M., Hlavaty L. ADHD treatments, sleep, and sleep problems: complex associations. Neurotherapeutics. 2012;3:509-517.  https://doi.org/10.1007/s13311-012-0130-0
  43. Romero-Peralta S., Cano-Pumarega I., Garcia-Malo C. et al. Treating restless legs syndrome in the context of sleep disordered breathing comorbidity. Eur Respir Rev. 2019;28:190061. https://doi.org/10.1183/16000617.0061-2019
  44. Roux F.J. Restless legs syndrome: impact on sleep-related breathing disorders. Respirology. 2013;2:238-245.  https://doi.org/10.1111/j.1440-1843.2012.02249.x
  45. Hvolby A. Associations of sleep disturbance with ADHD: implications for treatment. Atten Defic Hyperact Disord. 2015;1:1-18.  https://doi.org/10.1007/s12402-014-0151-0
  46. Staner L. Sleep disturbances, psychiatric disorders, and psychotropic drugs. Dialogues Clin Neurosci. 2005;4:323-334.  https://doi.org/10.31887/DCNS.2005.7.4/lstaner
  47. Davydova TV, Nevidimova TI, Vetrile LA, et al. The ratio of antibodies to neurotransmitters in the blood sera of women with alcohol dependence and depressive disorders. Byulleten’ eksperimental’noj biologii i mediciny. 2021;6:686-689. (In Russ.) https://doi.org/10.47056/0365-9615-2021-171-6-686-689
  48. Ara A., Jacobs W., Bhat I.A., McCall W.V. Sleep disturbances and substance use disorders: a bi-directional relationship. Psychiatric Annals. 2016;7:408-412. 
  49. Pieters S., Burk W.J., Van der Vorst H. et al. Prospective relationships between sleep problems and substance use, internalizing and externalizing problems. J Youth Adolesc. 2015;2:379-388.  https://doi.org/10.1007/s10964-014-0213-9
  50. Luca G., Peris L. Sleep Quality and Sleep Disturbance Perception in Dual Disorder Patients. J Clin Med. 2020;6:2015. https://doi.org/10.3390/jcm9062015
  51. Gentry J.R., Hill C., Malcolm R. New anticonvulsants: a review of applications for the management of substance abuse disorders. Ann Clin Psychiatry. 2012;4:233-245.  https://doi.org/10.1023/a:1021921118070
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.