Mental disorders in type 2 diabetes

Bobrov A.E.; Starostina E.G.; Agamamedova I.N.; Volodina M.N.; Karacheva Yu.V.; Nikitina T.E.; Parpara M.A.; Subbotnikova O.A.; Tsarenko D.M.; Nouwen A.; Lloyd C.; Sartorius N.

doi:https://doi.org/10.17116/jnevro202112107122

Bobrov A.E.

Serbsky National Medical Research Centre for Psychiatry and Narcology;
Pirogov Russian National Research Medical University

Starostina E.G.

Vladimirsky Moscow Regional Research and Clinical Institute («MONIKI»)

Agamamedova I.N.

Serbsky National Medical Research Centre for Psychiatry and Narcology

Volodina M.N.

Vladimirsky Moscow Regional Research and Clinical Institute («MONIKI»)

Karacheva Yu.V.

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University

Nikitina T.E.

Serbsky National Medical Research Centre for Psychiatry and Narcology

Parpara M.A.

Serbsky National Medical Research Centre for Psychiatry and Narcology

Subbotnikova O.A.

Serbsky National Medical Research Centre for Psychiatry and Narcology

Tsarenko D.M.

Serbsky National Medical Research Centre for Psychiatry and Narcology

Nouwen A.

Middlesex University

Lloyd C.

The Open University

Sartorius N.

Association for the Improvement of Mental Health Programmes

Mental disorders in type 2 diabetes

Authors:

Bobrov A.E., Starostina E.G., Agamamedova I.N., Volodina M.N., Karacheva Yu.V., Nikitina T.E., Parpara M.A., Subbotnikova O.A., Tsarenko D.M., Nouwen A., Lloyd C., Sartorius N.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(7): 22‑30

DOI: 10.17116/jnevro202112107122

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To cite this article:

Bobrov AE, Starostina EG, Agamamedova IN, et al. . Mental disorders in type 2 diabetes. S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(7):22‑30. (In Russ.)
https://doi.org/10.17116/jnevro202112107122

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

Использование инфографики авторами научных работ

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OBJECTIVE

To assess the prevalence of mental disorders in patients with type 2 diabetes mellitus (DM2) and their relationship with laboratory findings, somatic comorbidities and psychosocial consequences.

MATERIAL AND METHODS

In the frames of the INTERPRET-DD multicenter 200 T2DM patients from primary care (47 men and 153 women) from the Russian sample were studied. The psychometric assessment included MINI-6, HAMD-17, PHQ-9, PAID, WHO-5.

RESULTS

One hundred and seventeen patients (58.5%) have mental disorders. Current mental disorders were diagnosed in 93 (46.5%) of patients. Depression (depressive episode, recurrent depressive disorder, bipolar affective disorder type II) was identified in 34 (17.0%), dysthymia in 26 (13.0%), and anxiety spectrum disorders in 39 (19.5%). In about half of the cases, anxiety disorders were combined with depression. The most severe problems were observed in the patients with depression and dysthymia. Patients with social phobia had significantly higher levels of glycated hemoglobin compared to patients without mental disorders. The significant decrease of systolic arterial pressure and body mass index was observed in patients with agoraphobia compared to patients without mental disorders. In addition, there was an increased prevalence of chronic ischemic heart disease in recurrent depression, dysthymia and generalized anxiety disorder, higher prevalence of neuropathy in depressive episode and recurrent depression and nephropathy in panic disorder.

CONCLUSION

Depressive and anxiety disorders, as well as severe psychosocial problems, are consistently associated with T2DM. At the same time, concomitant somatic disorders and complications of DM2 are not just by chance comorbid to various forms of mental disorders, which allows for a new look at the problem of comorbidity/multimorbidity in T2DM.

Keywords:

type 2 diabetes mellitus

mental disorders

somatic complications of diabetes

multimorbidity

Authors:

Bobrov A.E.

Serbsky National Medical Research Centre for Psychiatry and Narcology;
Pirogov Russian National Research Medical University

Starostina E.G.

Vladimirsky Moscow Regional Research and Clinical Institute («MONIKI»)

Agamamedova I.N.

Serbsky National Medical Research Centre for Psychiatry and Narcology

Volodina M.N.

Vladimirsky Moscow Regional Research and Clinical Institute («MONIKI»)

Karacheva Yu.V.

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University

Nikitina T.E.

Serbsky National Medical Research Centre for Psychiatry and Narcology

Parpara M.A.

Serbsky National Medical Research Centre for Psychiatry and Narcology

Subbotnikova O.A.

Serbsky National Medical Research Centre for Psychiatry and Narcology

Tsarenko D.M.

Serbsky National Medical Research Centre for Psychiatry and Narcology

Nouwen A.

Middlesex University

Lloyd C.

The Open University

Sartorius N.

Association for the Improvement of Mental Health Programmes

Received:

25.11.2020

Accepted:

12.01.2021

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