Experience of using reamberin on the cognitive functions in children with epilepsy

Nosal’ L.A.; Simonova N.V.; Dorovskikh V.A.

doi:https://doi.org/10.17116/jnevro202012011153

Nosal’ L.A.

Amur State Medical Academy

Simonova N.V.

Amur State Medical Academy

Dorovskikh V.A.

Amur State Medical Academy

Experience of using reamberin on the cognitive functions in children with epilepsy

Authors:

Nosal’ L.A., Simonova N.V., Dorovskikh V.A.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(11): 53‑58

DOI: 10.17116/jnevro202012011153

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To cite this article:

Nosal’ LA, Simonova NV, Dorovskikh VA. Experience of using reamberin on the cognitive functions in children with epilepsy. S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(11):53‑58. (In Russ.)
https://doi.org/10.17116/jnevro202012011153

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

Использование инфографики авторами научных работ

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OBJECTIVE

To study the efficacy of reamberin in treatment of epilepsy in children and to evaluate its effect on the cognitive functions.

MATERIAL AND METHODS

The study included 51 patients with epilepsy aged 7 to 15 years. The children were divided into four groups depending on the prescribed treatment. The first study group (n=16) received intravenous reamberin once daily for 5 days in addition to carbamazepine. The second group (n=15) received intravenous reamberin once daily for 5 days in addition to valproic acid. Two comparison groups (10 patients each) received only carbamazepine or only valproic acid, respectively. Cognitive functions were assessed at admission and on the 6^th day of treatment using Schulte tables (10 words).

RESULTS AND CONCLUSION

Reamberin significantly increases the work efficiency by 19—21%, and workability degree by 8—12% compared with the patients of the control groups. An analysis of the effect of succinate-containing drug on auditory memory has shown that the volumes of short-term memory and long-term memory are by 1.8 times and 1.3 times, respectively, higher than those in the control groups. Thus, the addition of reamberin into the treatment of children with epilepsy should be considered clinically reasonable, and promising.

Keywords:

reamberin

epilepsy

cognitive functions

work efficiency

workability degree

auditory memory

Authors:

Nosal’ L.A.

Amur State Medical Academy

Simonova N.V.

Amur State Medical Academy

Dorovskikh V.A.

Amur State Medical Academy

Received:

31.08.2020

Accepted:

05.10.2020

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References:

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