Virus-associated progesterone-resistant chronic endometritis

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THE AIM OF THE STUDY

Was to analyze the literature data on the association of virus-associated chronic endometritis with the risk of hyperplastic processes of this localization, factors affecting the risk of malignancy, as well as the possibility of using markers of menstrual discharge for early diagnosis and evaluation of the effectiveness of treatment. To achieve this goal, a search was conducted for domestic and foreign publications in the international Pubmed citation system published over the past 15 years. Modern data on the main mechanisms of formation of hyperplastic processes in the endometrium, as well as on the risk factors of malignancy, are presented. Along with the use of traditional methods of diagnosing the pathology in question, the possibilities of identifying a disease marker in the menstrual secretions of the examined patients (glycodelin) are discussed both for early diagnosis and for evaluating effectiveness at treatment stages.

Keywords:

chronic endometritis

hyperplastic processes in the endometrium

menstrual discharge

endometrial flushes

glycodelin

diagnosis

sensitivity to hormone therapy

Authors:

Shvarev E.G.

Astrakhan State Medical University

ORCID: 0000-0003-0440-9236

Dikareva L.V.

Astrakhan State Medical University

ORCID: 0000-0001-9179-1669

Zoeva A.R.

Astrakhan State Medical University

ORCID: 0000-0001-8596-6514

Received:

13.12.2023

Accepted:

18.01.2024

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