Neopterin as a potential biomarker in neuropsychiatry

Shilov Yu.E.; Miroshnichenko I.I.

doi:https://doi.org/10.17116/jnevro2020120101125

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Abstract:

The importance of finding predictors or biomarkers of neuropsychiatric pathology, as well as methods of its prevention, treatment and early diagnosis is beyond question. The level of neopterin in body fluids is one of the possible biomarkers. Increased levels of neopterin in biological fluids (e.g., serum, cerebrospinal fluid or urine) are closely associated with various diseases associated with cellular immune response. The data presented in the review indicate the relevance of the study of neopterin concentrations in body fluids in patients with mental illness for the development of diagnostic and prognostic tests or as a pharmacodynamic marker of drug action.

Keywords:

neopterin

biomarker

inflammation

schizophrenia

depression

bipolar disorder

autism

kynurenines

Authors:

Shilov Yu.E.

Mental Health Research Center

Miroshnichenko I.I.

Mental Health Research Center

SPIN RSCI: 4117-9703
Scopus AuthorID: 7006095496
ResearcherID: D-1488-2018
ORCID: 0000-0003-4950-5336

Received:

01.11.2019

Accepted:

26.06.2020

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References:

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