The possibilities of predicting and reducing the risk of breast cancer in women against the background of the use of assisted reproductive technologies

Belotserkovtseva L.D.; Klimova N.V.; Kuznetsov A.A.

doi:https://doi.org/10.17116/rosakush20252501159

Belotserkovtseva L.D.

Surgut State University;
Surgut District Clinical Center for Maternal and Child Health

ORCID: 0000-0003-2768-8434

Klimova N.V.

Surgut State University;
Surgut District Clinical Center for Maternal and Child Health

ORCID: 0000-0003-4589-6528

Kuznetsov A.A.

Surgut State University;
Surgut District Clinical Center for Maternal and Child Health

ORCID: 0000-0003-4780-7146

The possibilities of predicting and reducing the risk of breast cancer in women against the background of the use of assisted reproductive technologies

Authors:

Belotserkovtseva L.D., Klimova N.V., Kuznetsov A.A.

More about the authors

Journal: Russian Bulletin of Obstetrician-Gynecologist. 2025;25(1): 59‑64

DOI: 10.17116/rosakush20252501159

Read: 871 times

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To cite this article:

Belotserkovtseva LD, Klimova NV, Kuznetsov AA. The possibilities of predicting and reducing the risk of breast cancer in women against the background of the use of assisted reproductive technologies. Russian Bulletin of Obstetrician-Gynecologist. 2025;25(1):59‑64. (In Russ.)
https://doi.org/10.17116/rosakush20252501159

Подписка 2026 Российский вестник акушера-гинеколога (Russian Bulletin of Obstetrician-Gynecologist)

Использование инфографики авторами научных работ

OBJECTIVE

To study the possibility of predicting the development of breast cancer against the background of the use of assisted reproductive technologies and to develop measures to reduce the risk of its development.

MATERIAL AND METHODS

Data from 5000 protocols of assistive reproductive technologies in 4500 patients were analyzed. All 4500 patients who planned pregnancy were necessarily examined by a mammologist-oncologist. The main group consisted of 77 patients who had used the largest (5 or more) number of methods of assisted reproductive technologies in their anamnesis. The data of the patients of the main group were analyzed by six independent experts — mammological oncologists. The expert information was processed using ordinal regression. The control group included 50 patients in whom assisted reproductive technologies were not used. Results. The methods of assessing the risk of developing breast cancer are analyzed. A model for predicting breast cancer in women who have undergone assisted reproductive technology procedures has been developed. The calculation of individual risks of breast cancer development in the groups of patients undergoing assisted reproductive technology procedures and the control group was carried out.

CONCLUSION

The incidence of breast cancer may depend on a large number of factors, the most significant of which is the initial condition of the breast according to sonography and mammography.

Keywords:

breast cancer

risk factors for development

cohort study

assisted reproductive technologies

Authors:

Belotserkovtseva L.D.

Surgut State University;
Surgut District Clinical Center for Maternal and Child Health

ORCID: 0000-0003-2768-8434

Klimova N.V.

Surgut State University;
Surgut District Clinical Center for Maternal and Child Health

ORCID: 0000-0003-4589-6528

Kuznetsov A.A.

Surgut State University;
Surgut District Clinical Center for Maternal and Child Health

ORCID: 0000-0003-4780-7146

Received:

16.05.2024

Accepted:

20.06.2024

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