The problem of infectious diseases in pregnant women and congenital infection in children is important for obstetricians-gynecologists, neonatologists, infectious disease specialists, neurologists. 11 March 2020. A COVID-19 pandemic has been declared by the World Health Organization (WHO). At present, the infection caused by the novel coronavirus SARS-CoV-2 is not losing its urgency. Pregnant women and newborns belong to the risk group of severe course of COVID-19, high risk of preterm labor, latent congenital infection, perinatal pathology and other unfavorable pregnancy outcomes. There are studies by foreign and Russian authors to assess the course of pregnancy in women who have had a new coronavirus infection during or before the pregnancy, but the course of pregnancy in women with an operated uterus and a new coronavirus infection has not been studied sufficiently. It is known that coronavirus infection has a wave-like course, with each new wave leading to more severe conditions in pregnant women and newborns, and to a course of latent congenital infection. For example, the first wave of COVID-19 resulted in virtually no obstetric complications. The second wave resulted in an increased incidence of preterm labor, with newborns requiring close attention and often observation in the intensive care unit. The third wave, with the emergence of the COVID-19 delta strain, resulted in increased maternal mortality, asymptomatic congenital infection and, consequently, worse perinatal outcomes. At the same time, there was an increase in the frequency of abdominal delivery for maternal and fetal reasons. In the fourth wave, maternal mortality declined, but fetuses and newborns were more likely to have growth retardation, fetoplacental insufficiency, prematurity and congenital infection. Until 2002, coronaviruses in humans were thought to cause only mild respiratory infections and gastroenteritis in newborns. In 2002-2003 there was an outbreak of SARS-CoV-1 infection with the development of severe acute respiratory syndrome, in 2012. — An outbreak of MERS-CoV-infection (periodic outbreaks of infection caused by this type of coronavirus are still registered). Congenital infections are characterized by polyetiological agents, polymorphism of clinical manifestations, and lack of pathognomonic features. Taking into account these facts, it is necessary to carefully monitor the course of pregnancy taking into account the risk of pregnancy complications.