OBJECTIVE

To assess the impact of maternal age at first birth and single pregnancy on the course of gestation, delivery and outcomes for newborns.

MATERIAL AND METHODS

A retrospective single-center study based on the Surgut Clinical Perinatal Center of 5638 first-time mothers with singleton births older than 18 years for 2018—19. The main outcomes included gestational diabetes, hypertension, preterm labor, obstetric interventions and outcomes for newborns. The comparison was made between the age groups 18—29, 30—34 and over 35 years old.

RESULTS

Primiparas over 35 years aged have an increased risk of gestational hypertension (9% vs 19.9%, p<0.001), preeclampsia (3.3% vs 5.7%, p=0.028), gestational diabetes (10% vs 27.7%, p<0.001), caesarean section (19.8% vs 69.2%, p<0.001) and preterm labor (5.9% vs 8.5%, p=0.013) that, in turn, entails an increase in the number of hospitalizations of children in the intensive care unit and intensive care of newborns. The risk of very early preterm birth (22—27 + 6 weeks) is increased in primiparas aged 30—34 compared to primiparas 18—29 years old (0.4% vs 1.1%, p=0.028). At the same time, perinatal mortality, Apgar score <7 at 5 minutes, and duration of hospitalization of premature newborns did not differ in the compared groups.

CONCLUSION

The risk of gestational hypertension, preeclampsia, gestational diabetes, the frequency of preterm birth, and the number of surgical interventions was significantly increased in first-time mothers over 30 years of age that comparable outcomes for newborns.