Postoperative pain as a cause of hypertension progression in women with preeclampsia after cesarean section

Davydov V.V.; Safonov V.P.

doi:https://doi.org/10.17116/pain20252302183

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OBJECTIVE

To analyze the role of postoperative pain syndrome for progression of hypertension in women with preeclampsia after cesarean section.

MATERIAL AND METHODS

We reviewed the PubMed/MEDLINE and eLibrary databases throughout 5 years.

RESULTS

A review is devoted to response of renin-angiotensin-aldosterone and sympathetic nervous systems of arterial pressure control to postoperative pain syndrome. Their characteristics and changes following preeclampsia are described. Current clinical and experimental data on mechanisms of activation under postoperative pain syndrome are presented. The authors discuss the causes of arterial hypertension progression in women with preeclampsia in early postoperative period after cesarean section from the position of activation of renin-angiotensin-aldosterone and sympathetic nervous systems provoked by complication of pregnancy and consequences of surgical treatment.

CONCLUSION

Women with preeclampsia have been found to have increased activity of renin-angiotensin-aldosterone and sympathetic nervous systems. Progression of arterial hypertension after cesarean section in these patients may be associated with additional activation of these systems due to postoperative pain syndrome.

Keywords:

postoperative pain syndrome

cesarean section

arterial hypertension

renin-angiotensin-aldosterone system

sympathetic nervous system

Authors:

Davydov V.V.

Altai State Medical University

ORCID: 0000-0001-7667-910X

Safonov V.P.

Altai State Medical University

ORCID: 0009-0002-9822-1604

Received:

02.09.2024

Accepted:

25.11.2024

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References:

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