Vaccination against COVID-19 in pregnancy is safe and effective (literature review)

Adamyan L.V.; Filippov O.S.; Kharchenko E.I.; Stepanian A.A.; Aznaurova Ya.B.; Konysheva O.V.

doi:https://doi.org/10.17116/repro20212705113

Close metadata

Recommended articles:

Localization features of FAP-positive activated stromal cells in fibrosis in patients with new coronavirus infection COVID-19. Russian Journal of Archive of Pathology. 2024;(6):5-14

The role of drug Cytoflavin in the correction of dysautonomia in patients with post-COVID syndrome. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(11):140-146

Laparoscopic appendectomy for appendiceal mucocele in a patient with COVID-19. Endoscopic Surgery. 2024;(6):41-45

Factors of adherence to vaccination of the Arkhangelsk region adult population. Russian Journal of Preventive Medicine. 2024;(12):92-99

Long-term outcomes in patients after hospital treatment for COVID-19 (three-year follow-up data). Russian Journal of Preventive Medicine. 2024;(12):114-121

Peculiarities of placental microRNA expression in patients with preeclampsia and fetal growth restriction. Russian Bulletin of Obstetrician-Gynecologist. 2024;(6):14-25

Changes in the type of psychological component of the gestational dominant in pregnant women in the third trimester after completing the perinatal preparation program. Russian Bulletin of Obstetrician-Gynecologist. 2024;(6):66-71

Sexual function of women during pregnancy. Russian Bulletin of Obstetrician-Gynecologist. 2024;(6):112-117

Dynamics of Substance P and Filaggrin Levels on Combined Treatment of Atopic Dermatitis with Emollient and Topical Antipruritic Drug in Pregnant Women. Russian Journal of Clinical Dermatology and Venereology. 2024;(6):662-666

Selective anosmia for monomolecular odorants in a cohort of young individuals. Russian Rhinology. 2024;(4):262-268

Abstract:

This review provides current information on safety and effectiveness of COVID-19 vaccines for pregnant and lactating patients. Various vaccine types, information regarding reproductive toxicology studies and vaccines efficacy against variants of concern are described in the article. The review also reflects practice guidelines of international professional communities on the use of COVID-19 vaccines in pregnancy, including the World Health Organization, RCOG (Royal College of Obstetricians and Gynecologists), ACOG (American College of Obstetricians and Gynecologists), RANZCOG (Royal Australian and New Zealand College of Obstetricians and Gynaecologists), etc. Currently, there is no evidence of a negative impact of COVID-19 vaccines on male and women’s reproductive health. On the other hand, the negative consequences of COVID-19 infection are well known both on the reproductive health of men and on the course and outcomes of pregnancy. Results of analysis of data on the course of pregnancy, childbirth, the postpartum period and the condition of newborns in 891 patients with coronavirus infection and in 1694 patients without coronavirus infection of the obstetric department of the Filatov City Clinical Hospital No. 15 for the period from January 01, 2020 to April 25, 2021. It was revealed that patients with coronavirus infection have a higher risk of preterm birth, a higher probability of having premature babies, and a higher percentage of operative delivery, than in patients without coronavirus infection. Newborn children in patients with coronavirus infection were more often admitted to the intensive care unit, than children of patients without coronavirus infection. Patients with coronavirus infection have a higher perinatal mortality rate than patients without coronavirus infection. No data has been received to support vertical transmission of the virus from a mother infected with COVID-19 to her fetus. There were no specific changes in placental tissue in patients with coronavirus infection. Based on the available results of clinical studies on the safety and efficacy of COVID-19 vaccines, all mentioned professional communities (WHO, CDC, ACOG, RCOG, RANZCOG, etc.) strongly recommend getting COVID-19 vaccine for women who are pregnant or breastfeeding.

Keywords:

COVID-19

vaccines

pregnancy

lactating patients

Authors:

Adamyan L.V.

Moscow State Medical and Dental University named after A.I. Evdokimov

SPIN RSCI: 9836-2713
Scopus AuthorID: 7006372422
ResearcherID: Q-1722-2018
ORCID: 0000-0002-3253-4512

Filippov O.S.

A.I. Evdokimov Moscow State University of Medicine and Dentistry

ORCID: 0000-0003-2654-1334

Kharchenko E.I.

Evdokimov Moscow State University of Medicine and Dentistry

Scopus AuthorID: 57180652400
ORCID: 0000-0002-3032-8416

Stepanian A.A.

Academia of Women’s Health and Endoscopic Surgery

Aznaurova Ya.B.

Evdokimov Moscow State University of Medicine and Dentistry

Konysheva O.V.

Evdokimov Moscow State University of Medicine and Dentistry

SPIN RSCI: 2155-1395
Scopus AuthorID: 57189642277
ORCID: 0000-0002-8064-2761

Received:

17.08.2021

Accepted:

18.08.2021

Close metadata

References:

Ellington S, Strid P, Tong VT, Woodworth K, Galang RR, Zambrano LD, Nahabedian J, Anderson K, Gilboa SM. Characteristics of women of reproductive age with laboratory-confirmed SARS-CoV-2 infection by pregnancy status — United States, January 22 — June 07, 2020. Morbidity and Mortality Weekly Report. 2020; 69(25):769-775. https://doi.org/10.15585/mmwr.mm6925a1
Hantoushzadeh S, Shamshirsaz AA, Aleyasin A, Seferovic MD, Aski SK, Arian SE, Pooransari P, Ghotbizadeh F, Aalipour S, Soleimani Z, Naemi M, Molaei B, Ahangari R, Salehi M, Oskoei AD, Pirozan P, Darkhaneh RF, Laki MG, Farani AK, Atrak S, Miri MM, Kouchek M, Shojaei S, Hadavand F, Keikha F, Hosseini MS, Borna S, Ariana S, Shariat M, Fatemi A, Nouri B, Nekooghadam SM, Aagaard K. Maternal death due to COVID-19. American Journal of Obstetrics and Gynecology. 2020;223(1):109.e1-109.e16. https://doi.org/10.1016/j.ajog.2020.04.030
Pierce-Williams RAM, Burd J, Felder L, Khoury R, Bernstein PS, Avila K, Penfield CA, Roman AS, DeBolt CA, Stone JL, Bianco A, Kern-Goldberger AR, Hirshberg A, Srinivas SK, Jayakumaran JS, Brandt JS, Anastasio H, Birsner M, O’Brien DS, Sedev HM, Dolin CD, Schnettler WT, Suhag A, Ahluwalia S, Navathe RS, Khalifeh A, Anderson K, Berghella V. Clinical course of severe and critical coronavirus disease 2019 in hospitalized pregnancies: a United States cohort study. American Journal of Obstetrics and Gynecology. MFM. 2020;2(3):100134. https://doi.org/10.1016/j.ajogmf.2020.100134
Juan J, Gil MM, Rong Z, Zhang Y, Yang H, Poon LC. Effect of coronavirus disease 2019 (COVID-19) on maternal, perinatal and neonatal outcome: systematic review. Ultrasound in Obstetrics and Gynecology. 2020;56:15-27.
Dashraath P, Wong JLJ, Lim MXK, Lim LM, Li S, Biswas A, Choolani M, Mattar C, Su LL. Coronavirus disease 2019 (COVID-19) pandemic and pregnancy. American Journal of Obstetrics and Gynecology. 2020;222:521-531. https://doi.org/10.1016/j.ajog.2020.03.021
Delahoy MJ, Whitaker M, O’Halloran A, Chai SJ, Kirley PD, Alden N, Kawasaki B, Meek J, Yousey-Hindes K, Anderson EJ, Openo KP, Monroe ML, Ryan PA, Fox K, Kim S, Lynfield R, Siebman S, Davis SS, Sosin DM, Barney G, Muse A, Bennett NM, Felsen CB, Billing LM, Shiltz J, Sutton M, West N, Schaffner W, Talbot HK, George A, Spencer M, Ellington S, Galang RR, Gilboa SM, Tong VT, Piasecki A, Brammer L, Fry AM, Hall AJ, Wortham JM, Kim L, Garg S; COVID-NET Surveillance Team. Characteristics and maternal and birth outcomes of hospitalized pregnant women with laboratory-confirmed COVID-19 — COVID-NET, 13 states, March 1 — August 22, 2020. Morbidity and Mortality Weekly Report. 2020;69(38):1347-1354. https://doi.org/10.15585/mmwr.mm6938e1
Papapanou M, Papaioannou M, Petta A, Routsi E, Farmaki M, Vlahos N, Siristatidis C. Maternal and neonatal characteristics and outcomes of COVID-19 in pregnancy: an overview of systematic reviews. International Journal of Environmental Research and Public Health. 2021;18(2):596. https://doi.org/10.3390/ijerph18020596
Della Gatta AN, Rizzo R, Pilu G, Simonazzi G. Coronavirus disease 2019 during pregnancy: a systematic review of reported cases. American Journal of Obstetrics and Gynecology. 2020;223(1):36-41. https://doi.org/10.1016/j.ajog.2020.04.013
Pachtman Shetty SL, Meirowitz N, Blitz MJ, Gadomski T, Weinberg CR. Myocardial injury associated with coronavirus disease 2019 in pregnancy. American Journal of Obstetrics and Gynecology. 2021; 224(2):229-232. https://doi.org/10.1016/j.ajog.2020.10.014
Mercedes BR, Serwat A, Naffaa L, Ramirez N, Khalid F, Steward SB, Feliz OGC, Kassab MB, Karout L. New-onset myocardial injury in pregnant patients with coronavirus disease 2019: a case series of 15 patients. American Journal of Obstetrics and Gynecology. 2021:224(4):387.e1-387.e9. https://doi.org/10.1016/j.ajog.2020.10.031
Angelidou A, Sullivan K, Melvin PR, Shui JE, Goldfarb IT, Bartolome R, Chaudhary N, Vaidya R, Culic I, Singh R, Yanni D, Patrizi S, Hudak ML, Parker MG, Belfort MB. Association of Maternal Perinatal SARS-CoV-2 Infection with Neonatal Outcomes during the COVID-19 Pandemic in Massachusetts. JAMA Network Open. 2021;4(4):e217523. https://doi.org/10.1001/jamanetworkopen.2021.7523
Logunov DY, Dolzhikova IV, Shcheblyakov DV, Tukhvatulin AI, Zubkova OV, Dzharullaeva AS, Kovyrshina AV, Lubenets NL, Grousova DM, Erokhova AS, Botikov AG, Izhaeva FM, Popova O, Ozharovskaya TA, Esmagambetov IB, Favorskaya IA, Zrelkin DI, Voronina DV, Shcherbinin DN, Semikhin AS, Simakova YV, Tokarskaya EA, Egorova DA, Shmarov MM, Nikitenko NA, Gushchin VA, Smolyarchuk EA, Zyryanov SK, Borisevich SV, Naroditsky BS, Gintsburg AL; Gam-COVID-Vac Vaccine Trial Group. Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia. The Lancet. 2021;397(10275):671-681. https://doi.org/10.1016/S0140-6736(21)00234-8
Jones I, Roy P. Sputnik V COVID-19 vaccine candidate appears safe and effective. The Lancet. 2021;397(10275):642-643. https://doi.org/10.1016/S0140-6736(21)00191-4
Gushchin VA, Dolzhikova IV, Shchetinin AM, Odintsova AS, Siniavin AE, Nikiforova MA, Pochtovyi AA, Shidlovskaya EV, Kuznetsova NA, Burgasova OA, Kolobukhina LV, Iliukhina AA, Kovyrshina AV, Botikov AG, Kuzina AV, Grousova DM, Tukhvatulin AI, Shcheblyakov DV, Zubkova OV, Karpova OV, Voronina OL, Ryzhova NN, Aksenova EI, Kunda MS, Lioznov DA, Danilenko DM, Komissarov AB, Tkachuck AP, Logunov DY, Gintsburg AL. Neutralizing Activity of Sera from Sputnik V-Vaccinated People against Variants of Concern (VOC: B.1.1.7, B.1.351, P.1, B.1.617.2, B.1.617.3) and Moscow Endemic SARS-CoV-2 Variants. Vaccines. 2021;9(7):779. https://doi.org/10.3390/vaccines9070779
Lopez Bernal J, Andrews N, Gower C, Gallagher E, Simmons R, Thelwall S, Stowe J, Tessier E, Groves N, Dabrera G, Myers R, Campbell CNJ, Amirthalingam G, Edmunds M, Zambon M, Brown KE, Hopkins S, Chand M, Ramsay M. Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant. The New England Journal of Medicine. 2021;385(7):585-594. https://doi.org/10.1056/NEJMoa2108891
World Health Organization. Pfizer BioNTech COVID-19 vaccine: What you need to know. Accessed August 18, 2021.
Goodman T, WHO/HQ/IVB. Update on WHO Interim Recommendations on COVID-19 Vaccination of Pregnant and Lactating Women. June 02, 2021. Accessed August 18, 2021. https://cdn.who.int/media/docs/default-source/2021-dha-docs/update-on-who-interim-recommendations-on-c-19-vaccination-for-pregnant-and-lactating-women-70-.pdf?sfvrsn=2c1d9ac8_1&download=true
FDA. Coronavirus (COVID-19) Update: FDA Authorizes Pfizer-BioNTech COVID-19 Vaccine for Emergency Use in Adolescents in Another Important Action in Fight Against Pandemic. Accessed August 18, 2021. https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-pfizer-biontech-covid-19-vaccine-emergency-use
CDC. COVID-19 Vaccine Safety in Adolescents Aged 12-17 Years — United States, December 14, 2020 — July 16, 2021. Accessed August 18, 2021.
ACOG. Statement of Strong Medical Consensus for Vaccination of Pregnant Individuals against COVID-19. Accessed August 18, 2021. https://www.acog.org/news/news-releases/2021/08/statement-of-strong-medical-consensus-for-vaccination-of-pregnant-individuals-against-covid-19
SMFM: Provider Considerations for Engaging in COVID-19 Vaccine Counseling with Pregnant and Lactating Patients. 7.30.2021 (last published 4.29.21). Accessed August 18, 2021. https://s3.amazonaws.com/cdn.smfm.org/media/3065/Provider_Considerations_for_Engaging_in_COVID_Vaccination_Considerations_8-12-21_%28final%29.pdf
The Royal Australian and New Zealand College of Obstetricians and Gynaecologists. COVID-19 Vaccination in Pregnant and Breastfeeding Women. August 6, 2021. Accessed August 18, 2021. https://ranzcog.edu.au/statements-guidelines/covid-19-statement/covid-19-vaccination-information
Joint Committee on Vaccination and Immunisation (JCVI). COVID-19 Vaccination: a Guide for all Women of Childbearing Age, Pregnant or Breastfeeding. 29 July 2021. Accessed August 18, 2021. https://www.gov.uk/government/publications/covid-19-vaccination-women-of-childbearing-age-currently-pregnant-planning-a-pregnancy-or-breastfeeding/covid-19-vaccination-a-guide-for-women-of-childbearing-age-pregnant-planning-a-pregnancy-or-breastfeeding
Royal College of Obstetricians and Gynecologists. COVID-19 Vaccines, Pregnancy and Breastfeeding. July 19, 2021. Accessed August 18, 2021.
Royal College of Obstetricians and Gynecologists. Information Sheet and Decision Aid. July 20, 2021. Accessed August 18, 2021. https://www.rcog.org.uk/globalassets/documents/guidelines/2021-02-24-combined-info-sheet-and-decision-aid.pdf
American Society for Reproductive Medicine. Patient Management and Clinical Recommendations during the Coronavirus (COVID-19) Pandemic. Update No. 16. 23 July, 2021. Accessed August 18, 2021. https://www. asrm.org/globalassets/asrm/asrm-content/news- and-publications/covid-19/covidtaskforceup date11.pdf
Stafford IA, Parchem JG, Sibai BM. The coronavirus disease 2019 vaccine in pregnancy: risks, benefits, and recommendations. American Journal of Obstetrics and Gynecology. 2021;224(5):484-495.
Craig AM, Hughes BL, Swamy GK. COVID-19 vaccines in pregnancy. American Journal of Obstetrics and Gynecology. MFM. 2021;3(2):100295. https://doi.org/10.1016/j.ajogmf.2020.100295
The American College of Obstetricians and Gynecologists. Vaccinating Pregnant and Lactating Patients against COVID-19. 2021. Accessed August 18, 2021. https://www.acog.org/clinical/clinical-guidance/practice-advisory/articles/2020/12/vaccinating-pregnant-and-lactating-patients-against-covid-19
Goldshtein I, Nevo D, Steinberg DM, et al. Association Between BNT162b2 Vaccination and Incidence of SARS-CoV-2 Infection in Pregnant Women. JAMA. 2021:e2111035. https://doi.org/10.1001/jama.2021.11035
Collier AY, McMahan K, Yu J, Tostanoski LH, Aguayo R, Ansel J, Chandrashekar A, Patel S, Apraku Bondzie E, Sellers D, Barrett J, Sanborn O, Wan H, Chang A, Anioke T, Nkolola J, Bradshaw C, Jacob-Dolan C, Feldman J, Gebre M, Borducchi EN, Liu J, Schmidt AG, Suscovich T, Linde C, Alter G, Hacker MR, Barouch DH. Immunogenicity of COVID-19 mRNA vaccines in pregnant and lactating women. JAMA. 2021;325(23):2370-2380. https://doi.org/10.1001/jama.2021.7563
Shanes ED, Otero S, Mithal LB, Mupanomunda CA, Miller ES, Goldstein JA. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccination in Pregnancy: Measures of Immunity and Placental Histopathology. Obstetrics and Gynecology. 2021; 138(2):281-283. https://doi.org/10.1097/AOG.0000000000004457
Baden LR, El Sahly HM, Essink B, Kotloff K, Frey S, Novak R, Diemert D, Spector SA, Rouphael N, Creech CB, McGettigan J, Khetan S, Segall N, Solis J, Brosz A, Fierro C, Schwartz H, Neuzil K, Corey L, Gilbert P, Janes H, Follmann D, Marovich M, Mascola J, Polakowski L, Ledgerwood J, Graham BS, Bennett H, Pajon R, Knightly C, Leav B, Deng W, Zhou H, Han S, Ivarsson M, Miller J, Zaks T; COVE Study Group. Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine. The New England Journal of Medicine. 2021;384(5);403-416. https://doi.org/10.1056/NEJMoa2035389
Society for Maternal-Fetal Medicine. Society for Maternal-Fetal Medicine (SMFM) Statement: SARS-CoV-2 Vaccination in Pregnancy. Accessed August 18, 2021. https://s3.amazonaws.com/cdn.smfm.org/media/2591/SMFM_Vaccine_Statement_12-1-20_(final).pdf
Academy of Breastfeeding Medicine. Considerations for COVID-19 Vaccination in Lactation. ABM Statement. Accessed August 18, 2021. https://abm. memberclicks.net/abm-statement-considerations-for-covid-19-vaccination-in-lactation
Palmeira P, Quinello C, Silveira-Lessa AL, Zago CA, Carneiro-Sampaio M. IgG Placental Transfer in Healthy and Pathological Pregnancies. Clinical and Developmental Immunology. 2012;985646. https://doi.org/10.1155/2012/985646
Albrecht M, Arck PC. Vertically Transferred Immunity in Neonates: Mothers, Mechanisms and Mediators. Frontiers in Immunology. 2020;11:555. https://doi.org/10.3389/fimmu.2020.00555
Sakala IG, Honda-Okubo Y, Fung J, Petrovsky N. Influenza immunization during pregnancy: benefits for mother and infant. Human Vaccines and Immunotherapeutics. 2016;12:3065-3071.
Blanchard-Rohner G, Meier S, Bel M, Combescure C, Othenin-Girard V, Swali RA, Martinez de Tejada B, Siegrist CA. Influenza vaccination given at least 2 weeks before delivery to pregnant women facilitates transmission of seroprotective influenza-specific antibodies to the newborn. The Pediatric Infectious Disease Journal. 2013;32:1374-1380. https://doi.org/10.1097/01.inf.0000437066.40840.c4
Mangtani P, Neuzil K, Nohynek H, Pless R, Lambach P, Zuber P. Safety of immunization during pregnancy: a review of the evidence of selected inactivated and live attenuated vaccines. Vaccine. 2014; 32(52):7057-7064. https://doi.org/10.1016/j.vaccine.2014.09.052
CDC. Tdap Effectiveness for Infant if Mother Vaccinated during Pregnancy. Accessed August 18, 2021. https://www.cdc.gov/pertussis/pregnant/hcp/vaccine-effectiveness.html
CDC. Flu Vaccine Safety and Pregnancy. Accessed August 18, 2021. https://www.cdc.gov/flu/highrisk/qa_vacpregnant.htm
Edlow AG, Li JZ, Collier AY, Atyeo C, James KE, Boatin AA, Gray KJ, Bordt EA, Shook LL, Yonker LM, Fasano A, Diouf K, Croul N, Devane S, Yockey LJ, Lima R, Shui J, Matute JD, Lerou PH, Akinwunmi BO, Schmidt A, Feldman J, Hauser BM, Caradonna TM, De la Flor D, D’Avino P, Regan J, Corry H, Coxen K, Fajnzylber J, Pepin D, Seaman MS, Barouch DH, Walker BD, Yu XG, Kaimal AJ, Roberts DJ, Alter G. Assessment of Maternal and Neonatal SARS-CoV-2 Viral Load, Transplacental Antibody Transfer, and Placental Pathology in Pregnancies during the COVID-19 Pandemic. JAMA Network Open. 2020;3(12): e2030455. https://doi.org/10.1001/jamanetworkopen.2020.30455
Gilbert P, Rudnick C. Newborn Antibodies to SARS-CoV-2 detected in cord blood after maternal vaccination. medRxiv. 2021.02.03. 21250579. https://doi.org/10.1101/2021.02.03.21250579
Pfizer-BioNTech. Pfizer and BioNTech Commence Global Clinical Trial to Evaluate COVID-19 Vaccine in Pregnant Women. Accessed August 18, 2021. https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-commence-global-clinical-trial-evaluate
Bowman CJ, Bouressam M, Campion SN, Cappon GD, Catlin NR, Cutler MW, Diekmann J, Rohde CM, Sellers RS, Lindemann C. Lack of effects on female fertility and prenatal and postnatal offspring development in rats with BNT162b2, a mRNA-based COVID-19 vaccine. Reproductive Toxicology. 2021;103:28-35. https://doi.org/10.1016/j.reprotox.2021.05.007
FDA Briefing Document. Moderna COVID-19 Vaccine. Vaccines and Related Biological Products Advisory Committee Meeting December 17, 2020. Accessed August 18, 2021. https://www.fda.gov/media/144434/download
FDA. Fact Sheet for Healthcare Providers Administering Vaccine (Vaccination Providers) Emergency Use Authorization (eua) of the Janssen COVID-19 Vaccine to Prevent Coronavirus Disease 2019 (COVID-19). Accessed August 18, 2021. https://www.fda.gov/media/146304/download
CDC. V-safe COVID-19 Vaccine Pregnancy Registry. Accessed August 18, 2021. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/vsafepregnancyregistry.html
Shimabukuro TT, Kim SY, Myers TR, Moro PL, Oduyebo T, Panagiotakopoulos L, Marquez PL, Olson CK, Liu R, Chang KT, Ellington SR, Burkel VK, Smoots AN, Green CJ, Licata C, Zhang BC, Alimchandani M, Mba-Jonas A, Martin SW, Gee JM, Meaney-Delman DM; CDC v-safe COVID-19 Pregnancy Registry Team. Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons. The New England Journal of Medicine. 2021;384(24): 2273-2282. https://doi.org/10.1056/NEJMoa2104983
CDC. Vaccine Adverse Event Reporting System (VAERS). Accessed August 18, 2021. https://www.cdc.gov/vaccinesafety/ensuringsafety/monitoring/vaers/index.html
ACOG. Ethical Issues with Vaccination in Obstetrics and Gynecology. Accessed August 18, 2021. https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2021/07/ethical-issues-with-vaccination-in-obstetrics-and-gynecology
Elagin VV, Adamyan LV, Vechorko VI, Doroshenko DA, Dashko AA, Filippov OS, Stepanian AA, Medvedeva IV. Vaccination against COVID-19 and male reproductive health (preliminary data). Problemy Reproduktsii. 2021;27(4). (In Russ.) https://doi.org/10.17116/repro2021270410
Adamyan LV, Vechorko VI, Elagin VV, Dashko AA, Doroshenko DA, Stepanian AA, Medvedeva IV, Sorokin MI, Suntsova MV, Efimov VO, Buzdin AA. COVID-19 vaccine does not affect male reproductive health (based on RNA-sequencing data). Problemy Reproduktsii. 2021;27(5). (In Russ.) https://doi.org/10.17116/repro2021270510
Dashko AA, Elagin VV, Kiseleva YuYu, Doroshenko DA, Adamyan LV, Vechorko VI. The influence of a new coronavirus infection on male fertility (preliminary data). Problemy Reproduktsii. 2020; 26(6):83-88. (In Russ.) https://doi.org/10.17116/repro20202606183
Adamyan L, Elagin V, Vechorko V, Stepanian A, Dashko A, Doroshenko D, Aznaurova Y, Sorokin M, Suntsova M, Garazha A, Buzdin A, COVID-19 — associated inhibition of energy accumulation pathways in human semen samples. F&S Science. 2021. https://doi.org/10.1016/j.xfss.2021.07.004
Adamyan LV, Vechorko VI, Filippov OS, Konysheva OV, Kharchenko EI, Fattakhova DN. New coronavirus infection (COVID-19). The outcomes of childbirth in women with COVID-19 and without COVID-19 during the pandemic (data from the obstetric department of the GBUZ “GKB No. 15 DZM”). Problemy Reproduktsii. 2021;27(3-2):15-22. (In Russ.) https://doi.org/10.17116/repro20212703215