Терапевтический потенциал кверцетина и его производных против COVID-19

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Кверцетин — природный флавоноид, обладающий широким спектром биологической активности. Это соединение плохо проникает в мозг, однако при стрессе проявляет нейрозащитные свойства, связанные, вероятно, с воздействием на гематоэнцефалический барьер (ГЭБ). Нарушение работы ГЭБ может отвечать за инвазию возбудителя новой коронавирусной инфекции (COVID-19) в мозг с развитием неврологических симптомов. Кверцетин обладает способностью подавлять размножение вирусов, окислительный стресс и воспалительную реакцию, а также предотвращать образование микротромбов. Этот потенциал кверцетина может быть полезным при лечении COVID-19 и его отдаленных последствий.

Ключевые слова:

кверцетин

COVID-19

SARS-CoV-2

воспаление

окислительный стресс

нейропротекция

гематоэнцефалический барьер

Авторы:

Катасонов А.Б.

ФГБНУ «Научный центр психического здоровья»

ORCID: 0000-0002-1450-5769

Дата поступления:

04.02.2025

Дата принятия в печать:

14.02.2025

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