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Ikonnikova E.V.

Central State Medical Academy of Administrative Directorate of the President of the Russian Federation;
Institute of Plastic Surgery and Cosmetology

Manturova N.E.

Pirogov Russian National Research Medical University;
Institute of Plastic Surgery and Cosmetology

Kruglova M.S.

School No. 518

Systemic therapy of delayed inflammatory reactions after the introduction of various types of cosmetic fillers. Part 1

Authors:

Ikonnikova E.V., Manturova N.E., Kruglova M.S.

More about the authors

Journal: Russian Journal of Clinical Dermatology and Venereology. 2021;20(3): 85‑91

DOI: 10.17116/klinderma20212003185

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To cite this article:

Ikonnikova EV, Manturova NE, Kruglova MS. Systemic therapy of delayed inflammatory reactions after the introduction of various types of cosmetic fillers. Part 1. Russian Journal of Clinical Dermatology and Venereology. 2021;20(3):85‑91. (In Russ.)
https://doi.org/10.17116/klinderma20212003185

 
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Delayed inflammatory reactions with dermal fillers are a relatively rare side effect. However, due to the steady increased quantity of contour plastics procedures, the number of such complications naturally increases. This type of complication is characterized by a tendency to a prolonged course of the inflammatory process and its frequent recurrence, due to which, in some cases, fibrotic changes in tissues, their deformation, impaired microcirculation, and the appearance of stagnant erythema occur. All this leads often to the development of pronounced aesthetic deficiencies and, as a consequence, to severe psycho-emotional disturbances in such patients. External therapy and intra-lesion injections described in detail by many authors are not always effective. In such cases, systemic therapy comes to the force allowing not only to stop outbreaks of inflammatory reactions but also to carry out their therapy with high efficiency that is especially important in patients with permanent fillers.

OBJECTIVE OF THE REVIEW

A detailed description of the use of glucocorticosteroid systemic therapy in cosmetology practice. The mechanism of action of drugs in this group is shown, a comparative analysis of treatment protocols used in world practice, possible side effects of therapy and the clinical experience of the authors are presented.

Keywords:

complications
fillers
permanent fillers
hyaluronic acid
delayed-type hypersensitivity
autoimmune reactions

Authors:

Ikonnikova E.V.

Central State Medical Academy of Administrative Directorate of the President of the Russian Federation;
Institute of Plastic Surgery and Cosmetology

Manturova N.E.

Pirogov Russian National Research Medical University;
Institute of Plastic Surgery and Cosmetology

Kruglova M.S.

School No. 518

Received:

25.02.2021

Accepted:

05.04.2021

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