Surgical treatment of thoracic aortic prosthesis and stent-graft infection

Charchyan ER, Kakabadze AG, Neizvestnykh DP, et al. . Surgical treatment of thoracic aortic prosthesis and stent-graft infection. Russian Journal of Cardiology and Cardiovascular Surgery. 2025;18(3):335‑342. (In Russ., In Engl.)
https://doi.org/10.17116/kardio202518031335

Подписка 2026 Кардиология и сердечно-сосудистая хирургия (Russian Journal of Cardiology and Cardiovascular Surgery)

Использование инфографики авторами научных работ

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OBJECTIVE

To demonstrate treatment of thoracic aortic prosthesis infection after open replacement and TEVAR for various thoracic aortic diseases.

MATERIAL AND METHODS

We retrospectively analyzed 14 patients with infectious lesion of descending thoracic aorta after open and endovascular interventions between 2013 and 2024.

RESULTS

Early postoperative complications included sepsis and multiple organ failure, pleural empyema (with thoracoscopic debridement in two cases) and respiratory failure. In two cases, patients who underwent esophageal defect suturing required additional intervention due to anastomotic suture failure and infection progression. Subtotal esophageal resection was performed. In-hospital mortality was 15% (2 out of 13). The causes of mortality were purulent-septic complications and multiple organ failure in early postoperative period, as well as acute cardiovascular failure due to massive blood loss. Long-term mortality was 18% (2 out of 11). The causes of mortality were cancer progression, as well as recurrent infection and sepsis.

CONCLUSION

Infection of thoracic aortic prosthesis, including stent grafts, remains a serious complication with high mortality rate. In our study, more favorable results were observed after extraanatomical bypass. However, it is impossible to unambiguously assess the effectiveness of the «in situ» method due to small sample size.

Keywords:

stent graft infection

prosthesis infection

complications

TEVAR

Authors:

Charchyan E.R.

Petrovsky National Research Centre of Surgery

SPIN RSCI: 4641-0523
Scopus AuthorID: 14044681400
ORCID: 0000-0002-0488-2560

Kakabadze A.G.

Petrovsky Russian Scientific Center of Surgery

ORCID: 0000-0003-3303-2570

Neizvestnykh D.P.

Petrovsky National Research Center of Surgery

ORCID: 0000-0001-8609-4009

Breshenkov D.G.

Petrovsky National Research Center of Surgery

ORCID: 0000-0002-9459-9282

Chakal D.A.

Petrovsky National Research Center of Surgery

ORCID: 0000-0003-3542-0315

Gens A.P.

B.V. Petrovsky National Research Centre of Surgery

ORCID: 0009-0003-8861-6474

Stepanenko A.B.

Petrovsky National Research Centre of Surgery

SPIN RSCI: 7602-1603
Scopus AuthorID: 7005363160
ORCID: 0000-0002-8768-127X

Belov Yu.V.

Petrovsky National Research Center of Surgery;
Sechenov First Moscow State Medical University

SPIN RSCI: 2740-1439
Scopus AuthorID: 7101862336
ResearcherID: 7101862336
ORCID: 0000-0002-9280-8845

Received:

14.02.2025

Accepted:

20.03.2025

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References:

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