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Gavrilenko A.V.

Russian Scientific Center for Surgery named after Academician B.V. Petrovsky;
Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)

Abramyan A.V.

Russian Scientific Center for Surgery named after Academician B.V. Petrovsky

Lopatkin E.I.

Sechenov First Moscow State Medical University (Sechenov University)

Zhi L.

Sechenov First Moscow State Medical University (Sechenov University)

Rasulov K.G.

Sechenov First Moscow State Medical University (Sechenov University)

Shalygo M.A.

Sechenov First Moscow State Medical University (Sechenov University)

Pogorelskaya E.A.

Sechenov First Moscow State Medical University (Sechenov University)

Fomina E.V.

Sechenov First Moscow State Medical University (Sechenov University)

Risk factors of internal carotid artery tortuosity

Authors:

Gavrilenko A.V., Abramyan A.V., Lopatkin E.I., Zhi L., Rasulov K.G., Shalygo M.A., Pogorelskaya E.A., Fomina E.V.

More about the authors

Journal: Russian Journal of Cardiology and Cardiovascular Surgery. 2025;18(2): 150‑155

DOI: 10.17116/kardio202518021150

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Table of contents

RISK FACTORS OF INTERNAL CAROTID ARTERY TORTUOSITY
RISK FACTORS OF INTERNAL CAROTID ARTERY TORTUOSITY

To cite this article:

Gavrilenko AV, Abramyan AV, Lopatkin EI, et al. . Risk factors of internal carotid artery tortuosity. Russian Journal of Cardiology and Cardiovascular Surgery. 2025;18(2):150‑155. (In Russ.)
https://doi.org/10.17116/kardio202518021150

 
ЭндоКард
Подписка 2026 Кардиология и сердечно-сосудистая хирургия (Russian Journal of Cardiology and Cardiovascular Surgery)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

To determine the main factors contributing to internal carotid artery (ICA) tortuosity.

MATERIAL AND METHODS

The study included 180 patients divided into two groups: the study group (150 patients) and the control group (30 patients). Data were collected using a standardized questionnaire and medical records. CT angiography data were used including degree of ICA tortuosity and stenosis, as well as tortuosity index as ratio of length of tortuous and straight segments.

RESULTS

The risk assessment model for ICA tortuosity demonstrated high effectiveness with AUC 0.883 and statistical significance (p<0.001). The threshold value of logistic function was 0.846 with sensitivity and specificity 88.5% and 71.9%, respectively. Combination of risk factors such as arterial hypertension, age over 60 years and dyslipidemia significantly increases the likelihood of ICA tortuosity.

CONCLUSION

The study confirmed arterial hypertension, age over 60 years, smoking and dyslipidemia as the main risk factors of ICA tortuosity.

Keywords:

tortuosity
risk factors
internal carotid artery

Authors:

Gavrilenko A.V.

Russian Scientific Center for Surgery named after Academician B.V. Petrovsky;
Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)

Abramyan A.V.

Russian Scientific Center for Surgery named after Academician B.V. Petrovsky

Lopatkin E.I.

Sechenov First Moscow State Medical University (Sechenov University)

Zhi L.

Sechenov First Moscow State Medical University (Sechenov University)

Rasulov K.G.

Sechenov First Moscow State Medical University (Sechenov University)

Shalygo M.A.

Sechenov First Moscow State Medical University (Sechenov University)

Pogorelskaya E.A.

Sechenov First Moscow State Medical University (Sechenov University)

Fomina E.V.

Sechenov First Moscow State Medical University (Sechenov University)

Received:

20.10.2024

Accepted:

10.11.2024

Close metadata

References:

  1. Belov YuV, Isaev RM. Risk stratification in cardiovascular surgery. Pirogov Journal of Surgery 2014; 7:78-81. (In Russ.).
  2. Gavrilenko AV, Abramyan AV, Kuklin AV, Ofosu D. Internal carotid artery tortuosity: clinical features, diagnostics and surgical treatment. Russian Journal of Cardiology and Cardiovascular Surgery. 2016; 9(1):29-33. (In Russ.). https://doi.org/10.17116/kardio20169129-33
  3. Aghasadeghi F, Dehghan A. Evaluation of the association between the internal carotid artery and vertebral artery tortuosity and acute ischemic stroke using tortuosity index. Vascular. 2022; 32(2):424-432.  https://doi.org/10.1177/17085381221140163
  4. Huang H. Age and duration of hypertension are associated with carotid artery tortuosity. Frontiers in Neurology. 2024; 15.  https://doi.org/10.3389/fneur.2024.1307984
  5. Ikeda G, Tsuruta W, Nakai Y, et al. Anatomical risk factors for ischemic lesions associated with carotid artery stenting. Interventional Neuroradiology. 2014; 20(6):746-754.  https://doi.org/10.15274/inr-2014-10075
  6. Kamenskiy A, Pipinos I, Carson J, et al. Age and disease-related geometric and structural remodeling of the carotid artery. Journal of Vascular Surgery. 2015; 62(6):1521-1528. https://doi.org/10.1016/j.jvs.2014.10.041
  7. Krejza J, Arkuszewski M, Kasner S, et al. Carotid artery diameter in men and women and the relation to body and neck size. Stroke. 2006; 37(4):1103-1105. https://doi.org/10.1161/01.str.0000206440.48756.f7
  8. Li M, Niu L, Qin B, et al. Confocal comparison of corneal reinnervation after small incision lenticule extraction (smile) and femtosecond laser in situ keratomileusis (fs-lasik). Plos One. 2013; 8(12): e81435. https://doi.org/10.1371/journal.pone.0081435
  9. Liu J, Ke X, Lai Q. Increased tortuosity of bilateral distal internal carotid artery is associated with white matter hyperintensities. Acta Radiologica. 2020; 62(4):515-523.  https://doi.org/10.1177/0284185120932386
  10. Liu M. Impact of latent virus infection in the cornea on corneal healing after small incision lenticule extraction. Microorganisms. 2023; 11(10):2441. https://doi.org/10.3390/microorganisms11102441
  11. Narloch J, Piasecki A, Zięcina P, et al. Is aspiration an effective acute stroke treatment in older adults? Frontiers in Neurology. 2023;14.  https://doi.org/10.3389/fneur.2023.1149531
  12. Patel S. Subbasal nerve density and corneal sensitivity after laser in situ keratomileusis. Archives of Ophthalmology. 2010; 128(11):1413. https://doi.org/10.1001/archophthalmol.2010.253
  13. Raidah A, Jaramillo N, Serena G, Lev S, Ramanathan A. Tortuous carotid arteries and their clinical implications: a report of two cases. Cureus. 2023; 15 (3): e36953  https://doi.org/10.7759/cureus.36953
  14. Recchioni A, Sisó-Fuertes I, Hartwig A, et al. Short-term impact of fs-lasik and smile on dry eye metrics and corneal nerve morphology. Cornea. 2020; 39(7):851-857.  https://doi.org/10.1097/ico.0000000000002312
  15. Saba L, Sanfilippo R, Suri J, et al. Does carotid artery tortuosity play a role in stroke?. Canadian Association of Radiologists Journal. 2021; 72(4):789-796.  https://doi.org/10.1177/0846537121991057
  16. Shang K, Chen X, Chang C, et al. Arterial tortuosity and its correlation with white matter hyperintensities in acute ischemic stroke. Neural Plasticity. 2022; 1-10.  https://doi.org/10.1155/2022/4280410
  17. Voss S, Campanella C, Burri M, et al. Anatomical reasons for failure of dual‐filter cerebral embolic protection application in tavr: a ct‐based analysis. Journal of Cardiac Surgery. 2021; 36(12):4537-4545. https://doi.org/10.1111/jocs.16025
  18. Vries E, Pourier V, Laarhoven C, et al. Comparability of semiautomatic tortuosity measurements in the carotid artery. Neuroradiology. 2018; 61(2):147-153.  https://doi.org/10.1007/s00234-018-2112-3
  19. Wang H, Wang D, Wang J, et al. Extracranial internal carotid artery tortuosity and body mass index. Frontiers in Neurology. 2017;8.  https://doi.org/10.3389/fneur.2017.00508
  20. Wang L, Zhao F, Wang D, et al. Pressure drop in tortuosity/kinking of the internal carotid artery: simulation and clinical investigation. Biomed Research International. 2016; 1-8.  https://doi.org/10.1155/2016/2428970
  21. Wang Q, Liu C, Yan B, et al. Correlation of extracranial internal carotid artery tortuosity index and intraprocedural complications during carotid artery stenting. European Neurology. 2012;68(2):65-72.  https://doi.org/10.1159/000337682
  22. Welby J, Kim S, Carr C, et al. Carotid artery tortuosity is associated with connective tissue diseases. American Journal of Neuroradiology. 2019; 40 (10):1738-1743. https://doi.org/10.3174/ajnr.a6218
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