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Bervitskiy A.V.

FSBI «Federal Center for Neurosurgery» of the Ministry of Health of the Russian Federation;
Research Institute of Clinical and Experimental Lymphology — Branch of the Institute of Cytology and Genetics SB RAS;
Institute of Hydrodynamics. M.A. Lavrent'ev SB RAS

Moisak G.I.

FSBI «Federal Center for Neurosurgery» of the Ministry of Health of the Russian Federation;
Novosibirsk State University

Guzhin V.E.

FSBI «Federal Center for Neurosurgery» of the Ministry of Health of the Russian Federation

Amelina E.V.

Novosibirsk State University

Kalinovskiy A.V.

FSBI «Federal Center for Neurosurgery» of the Ministry of Health of the Russian Federation

Rzayev D.A.

Federal Center for Neurosurgery

Incidence and risk factors of venous thromboembolic events after resection of various brain tumors

Authors:

Bervitskiy A.V., Moisak G.I., Guzhin V.E., Amelina E.V., Kalinovskiy A.V., Rzayev D.A.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2021;85(3): 63‑75

DOI: 10.17116/neiro20218503163

Read: 4693 times

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Table of contents

INCIDENCE AND RISK FACTORS OF VENOUS THROMBOEMBOLIC EVENTS AFTER RESECTION OF VARIOUS BRAIN TUMORS
INCIDENCE AND RISK FACTORS OF VENOUS THROMBOEMBOLIC EVENTS AFTER RESECTION OF VARIOUS BRAIN TUMORS

To cite this article:

Bervitskiy AV, Moisak GI, Guzhin VE, Amelina EV, Kalinovskiy AV, Rzayev DA. Incidence and risk factors of venous thromboembolic events after resection of various brain tumors. Burdenko's Journal of Neurosurgery. 2021;85(3):63‑75. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20218503163

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)
МСФ на ЯМ
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Abstract:

Venous thromboembolic events (VTE) can significantly complicate postoperative period in neurosurgical patients. It is known that patients with brain tumors are especially susceptible to VTE.

OBJECTIVE

To determine the incidence and risk factors of VTE in patients with various brain tumors.

MATERIAL AND METHODS

All patients with brain tumors underwent surgery in 2019 (n=610). They were divided into the groups depending on tumor type: sellar region, intracerebral, extracerebral neoplasms and metastases. All patients underwent screening and prevention of VTE in accordance with the protocol accepted in the hospital. We analyzed the incidence of VTE in each group and significance of various risk factors.

RESULTS

Overall incidence of VTE was 14.9% (91 cases). Deep vein thrombosis (DVT) was the most common — 85 cases (93.4%). Less common events were DVT combined with pulmonary embolism (PE) (n=5, 5.5%) and PE alone (n=1; 1.1%). PE caused death in 2 cases (0.3%). In patients with sellar tumors, incidence was 21.7% [13.4%; 29.35%], among intracerebral tumors — 13.8% [9.04%; 18.62%], extracerebral neoplasms — 15.4% [11.02%; 19.69%], metastases — 7.9% [1.32%; 11.84%]. Univariate and multivariate analysis revealed some risk factors of VTEs such as gender, age, surgery time, length of ICU-stay over 12 hours, body mass index >30 kg/m2. Moreover, risk factors have different significance in patients with different types of tumors.

CONCLUSION

In this study, we found a high incidence of VTE among patients with brain tumors. Incidence and risk factors of VTE depend on the type of tumor.

Keywords:

thrombosis
thromboembolism
complication
pulmonary embolism
DVT
tumor

Authors:

Bervitskiy A.V.

FSBI «Federal Center for Neurosurgery» of the Ministry of Health of the Russian Federation;
Research Institute of Clinical and Experimental Lymphology — Branch of the Institute of Cytology and Genetics SB RAS;
Institute of Hydrodynamics. M.A. Lavrent'ev SB RAS

Moisak G.I.

FSBI «Federal Center for Neurosurgery» of the Ministry of Health of the Russian Federation;
Novosibirsk State University

Guzhin V.E.

FSBI «Federal Center for Neurosurgery» of the Ministry of Health of the Russian Federation

Amelina E.V.

Novosibirsk State University

Kalinovskiy A.V.

FSBI «Federal Center for Neurosurgery» of the Ministry of Health of the Russian Federation

Rzayev D.A.

Federal Center for Neurosurgery

Received:

17.09.2020

Accepted:

05.02.2021

Close metadata

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