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Martynov M.Yu.

N.I. Pirogov Russian National Medical Research University (Pirogov University);
City Clinical Hospital No. 1 named after N.I. Pirogov;
Federal Center for Brain and Neurotechnologies

Schmidt E.I.

City Clinical Hospital No. 1 named after N.I. Pirogov

Belikova L.P.

City Clinical Hospital No. 1 named after N.I. Pirogov

Lepeshkin B.S.

N.I. Pirogov Russian National Medical Research University (Pirogov University);
City Clinical Hospital No. 1 named after N.I. Pirogov

Neurological complications involving the cervical spine as a cause of adverse outcome in patients with rheumatoid arthritis

Authors:

Martynov M.Yu., Schmidt E.I., Belikova L.P., Lepeshkin B.S.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(6): 133‑140

DOI: 10.17116/jnevro2025125061133

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Table of contents

NEUROLOGICAL COMPLICATIONS INVOLVING THE CERVICAL SPINE AS A CAUSE OF ADVERSE OUTCOME IN PATIENTS WITH RHEUMATOID ARTHRITIS
NEUROLOGICAL COMPLICATIONS INVOLVING THE CERVICAL SPINE AS A CAUSE OF ADVERSE OUTCOME IN PATIENTS WITH RHEUMATOID ARTHRITIS

To cite this article:

Martynov MYu, Schmidt EI, Belikova LP, Lepeshkin BS. Neurological complications involving the cervical spine as a cause of adverse outcome in patients with rheumatoid arthritis. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(6):133‑140. (In Russ.)
https://doi.org/10.17116/jnevro2025125061133

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
 
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Использование инфографики авторами научных работ
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Abstract:

Rheumatoid arthritis (RA) is one of the most common autoimmune diseases. Erosive arthritis and pannus are key clinical features of RA, and the cervical spine (CS) involvement in RA is ranked 3rd in frequency after hand and foot joint involvement. Neurological complications in patients with the CS involvement significantly aggravate the course of RA and can cause an adverse outcome. Two clinical cases of RA patients with subluxation in the atlanto-occipital (AOJ) and atlanto-axial (AAJ) joints, pannus, and fatal outcome are presented. It was found that one of the first symptoms of AOJ and AAJ subluxations may be headache in the occipital region and pain in the upper cervical spine. The progression of instability in these joints leads first to transient and later persistent symptoms of involvement of the medulla oblongata and the cervical spinal cord. Early diagnosis of clinical manifestations, follow-up of radiological changes, and consultation with a neurosurgeon are important in these patients.

Keywords:

headache
neck pain
bulbar syndrome
myelopathy
rheumatoid arthritis
pannus
craniovertebral junction
atlanto-occipital joint
atlanto-axial joint
cervical spine

Authors:

Martynov M.Yu.

N.I. Pirogov Russian National Medical Research University (Pirogov University);
City Clinical Hospital No. 1 named after N.I. Pirogov;
Federal Center for Brain and Neurotechnologies

Schmidt E.I.

City Clinical Hospital No. 1 named after N.I. Pirogov

Belikova L.P.

City Clinical Hospital No. 1 named after N.I. Pirogov

Lepeshkin B.S.

N.I. Pirogov Russian National Medical Research University (Pirogov University);
City Clinical Hospital No. 1 named after N.I. Pirogov

Received:

26.02.2025

Accepted:

27.02.2025

Close metadata

References:

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