Comparison of minimally invasive and traditional surgical treatment of extramedullary tumors of the craniovertebral junction

Kaprovoy S.V.; Konovalov N.A.; Onoprienko R.A.; Strunina Yu.V.; Shmelev N.D.

doi:https://doi.org/10.17116/neiro20258905164

Kaprovoy S.V.

Burdenko Neurosurgical Center

ORCID: 0000-0001-8813-2793

Konovalov N.A.

Burdenko Neurosurgical Center;
Botkin Hospital

ORCID: 0000-0002-9976-948X

Onoprienko R.A.

Burdenko Neurosurgical Center

ORCID: 0000-0002-8637-9079

Strunina Yu.V.

Burdenko Neurosurgical Center

ORCID: 0000-0003-1696-4050

Shmelev N.D.

Burdenko Neurosurgical Center

ORCID: 0009-0005-7058-902X

Comparison of minimally invasive and traditional surgical treatment of extramedullary tumors of the craniovertebral junction

Authors:

Kaprovoy S.V., Konovalov N.A., Onoprienko R.A., Strunina Yu.V., Shmelev N.D.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2025;89(5): 64‑70

DOI: 10.17116/neiro20258905164

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To cite this article:

Kaprovoy SV, Konovalov NA, Onoprienko RA, Strunina YuV, Shmelev ND. Comparison of minimally invasive and traditional surgical treatment of extramedullary tumors of the craniovertebral junction. Burdenko's Journal of Neurosurgery. 2025;89(5):64‑70. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20258905164

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)

Использование инфографики авторами научных работ

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OBJECTIVE

To compare minimally invasive and traditional surgical treatment of extramedullary tumors of the craniovertebral junction (CVJ).

MATERIAL AND METHODS

The study included patients who underwent microsurgical resection of extramedullary tumors of the craniovertebral junction. Clinical and surgical parameters reflecting the effectiveness and safety of surgical methods used were analyzed.

RESULTS

The study included 61 patients (minimally invasive approaches (MISS) — 29 patients, traditional approaches (OPEN) — 32 patients). Total resection of tumor was achieved in most patients with high safety according to intraoperative and postoperative parameters. In two cases, redo surgery was required due to wound cerebrospinal fluid leakage and large CSF cyst in soft tissues. Mean hospital-stay was 7 days. VAS score of pain syndrome within surgical site at discharge averaged 2 points. Three months after surgery, pain syndrome was almost absent in all patients. There were no significant differences in parameters of neurophysiological monitoring (p=0.758).

CONCLUSION

Undoubtedly, further searching and improvement of minimally invasive surgical approaches with subsequent study of their effectiveness and safety are necessary in randomized clinical trials.

Keywords:

intradural extramedullary tumors

craniovertebral junction

surgical treatment

minimally invasive approach

Authors:

Kaprovoy S.V.

Burdenko Neurosurgical Center

ORCID: 0000-0001-8813-2793

Konovalov N.A.

Burdenko Neurosurgical Center;
Botkin Hospital

ORCID: 0000-0002-9976-948X

Onoprienko R.A.

Burdenko Neurosurgical Center

ORCID: 0000-0002-8637-9079

Strunina Yu.V.

Burdenko Neurosurgical Center

ORCID: 0000-0003-1696-4050

Shmelev N.D.

Burdenko Neurosurgical Center

ORCID: 0009-0005-7058-902X

Received:

17.06.2025

Accepted:

18.07.2025

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