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Kunelskaya N.L.
L. I. Sverzhevsky Research Clinical Institute of Otorhinolaryngology;
Pirogov Russian National Research Medical University
Zaoeva Z.O.
Sverzhevky Research Clinical Institute of Otorhinolaryngology
Vasilchenko N.O.
Sverzhevsky Research Clinical Institute of Otorhinolaryngology
Chugunova M.A.
Sverzhevky Research Clinical Institute of Otorhinolaryngology
Revazishvili S.D.
L.I. Sverzhevsky Research Clinical Institute of Otorhinolaryngology
Biochemical features of migraine pathogenesis
Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(4): 21‑26
Read: 577 times
To cite this article:
Kunelskaya NL, Zaoeva ZO, Vasilchenko NO, Chugunova MA, Revazishvili SD. Biochemical features of migraine pathogenesis. S.S. Korsakov Journal of Neurology and Psychiatry.
2025;125(4):21‑26. (In Russ.)
https://doi.org/10.17116/jnevro202512504121
The article addresses the main mechanisms of migraine pathogenesis in terms of biochemical features (neurotransmitter metabolism, neurochemistry, neurophysiology, and neurogenetics). The effect of hormones, electrolytes (magnesium, calcium, sodium), vitamins (vitamin D, B12), and other biologically active molecules (melatonin, L-carnitine, L-tryptophan) on the course of the disease is considered. Including some laboratory tests in the migraine diagnostic algorithm helps identify the secondary nature of headache and/or dizziness, manage therapeutic approaches, and adjust the prognosis and treatment outcomes.
Authors:
Kunelskaya N.L.
L. I. Sverzhevsky Research Clinical Institute of Otorhinolaryngology;
Pirogov Russian National Research Medical University
Zaoeva Z.O.
Sverzhevky Research Clinical Institute of Otorhinolaryngology
Vasilchenko N.O.
Sverzhevsky Research Clinical Institute of Otorhinolaryngology
Chugunova M.A.
Sverzhevky Research Clinical Institute of Otorhinolaryngology
Revazishvili S.D.
L.I. Sverzhevsky Research Clinical Institute of Otorhinolaryngology
Received:
13.12.2024
Accepted:
19.12.2024
List of references:
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