Evaluation of the effectiveness of the drug Cortexin in combination with the use of the application Aphasia.No (Afaziyam.Net) in the correction of speech disorders in patients with cerebral infarction

Kuznetsova E.B.

Razumovsky Saratov State Medical University

ORCID: 0000-0002-3979-3453

Selivanova J.V.

Saratov State University

ORCID: 0000-0003-2375-4131

Gerber A.V.

Razumovsky Saratov State Medical University

ORCID: 0009-0007-0221-5565

Evaluation of the effectiveness of the drug Cortexin in combination with the use of the application Aphasia.No (Afaziyam.Net) in the correction of speech disorders in patients with cerebral infarction

Authors:

Kuznetsova E.B., Selivanova J.V., Gerber A.V.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(11): 147‑151

DOI: 10.17116/jnevro2024124111147

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To cite this article:

Kuznetsova EB, Selivanova JV, Gerber AV. Evaluation of the effectiveness of the drug Cortexin in combination with the use of the application Aphasia.No (Afaziyam.Net) in the correction of speech disorders in patients with cerebral infarction. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(11):147‑151. (In Russ.)
https://doi.org/10.17116/jnevro2024124111147

Подписка 2025-2 (S.S. Korsakov Journal of Neurology and Psychiatry)

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OBJECTIVE

Assessing the effectiveness of using a complex that includes the use of the drug Cortexin and classes using the mobile application Aphasia.No (Afaziyam.Net) in working with speech disorders in patients with acute stroke.

MATERIAL AND METHODS

The study involved 71 patients aged from 40 to 85 years with diagnoses of the ONCM group (I63—I64), as well as complications aphasia, 50 of them consented to neuropsychological rehabilitation using the application Aphasia.No (Afaziyam.Net) and received the drug Cortexin as a peptide drug at a dose of 10 mg 2 times a day intramuscularly (IG). 21 patients made up the comparison group. To assess the effectiveness of the rehabilitation complex, the following psychodiagnostic methods were used: MoCA, MMSE, a set of tasks for the study of speech, writing, reading, and the HADS scale.

RESULTS

The average score based on the results of a comprehensive study of speech, writing and reading in the group on day 2 in the hospital was: speech — 141.8±21.6 (normal — 262 points); writing — 20.5±4.23 (normal — 44 points); reading — 14.5±1.87 (normal — 29 points) points. An examination before discharge in IG showed the following results: speech — 214.3±15.9; writing — 31.5±4.5; reading — 24.4±4.7 points. The differences compared to the baseline and the 2^nd group were statistically significant.

CONCLUSION

The complex treatment used in the work can be recommended as an effective tool in working with speech disorders in patients with acute stroke. In addition, the program has a positive effect on the psycho-emotional state.

Keywords:

stroke

acute cerebrovascular accident

aphasia

correction

Cortexin

Authors:

Kuznetsova E.B.

Razumovsky Saratov State Medical University

ORCID: 0000-0002-3979-3453

Selivanova J.V.

Saratov State University

ORCID: 0000-0003-2375-4131

Gerber A.V.

Razumovsky Saratov State Medical University

ORCID: 0009-0007-0221-5565

Received:

16.09.2024

Accepted:

09.10.2024

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