OBJECTIVE

To study the effectiveness of including remaxol in the rehabilitation treatment of patients after radical prostatectomy.

MATERIAL AND METHODS

The results of therapy of 65 patients after surgical intervention (radical prostatectomy) for benign prostatic hyperplasia (BPH) in the decompensation stage were analyzed. Depending on the nutritional and metabolic support scheme in the postoperative period, the patients were divided into 2 groups: in the 1st (n=30) they received remaxol (inosine+meglumine+methionine+nicotinamide+succinic acid): 400 ml intravenously by drip at a rate of 40—60 drops (2—3 ml) per minute once a day for 10 days, in the 2nd (n=35) they carried out standard treatment. Nutritional deficiency and the risk of its development were assessed using appropriate scales.

RESULTS

In patients with decompensated BPH, there were signs of moderate nutritional deficiency in the postoperative period, which was accompanied by high nutritional risk in most patients in Group 1 (80%) and in 71.4% of the comparison group. After the correction, when assessing nutritional deficiency, it was found that the proportion of moderate forms decreased by 3.1 times in the main group and 1.76 times in the comparison group, p> 0.05, and the nutritional risk decreased by 2.6 and 1.5 times, respectively, p> 0.05. This effect can apparently be associated with the antioxidant and hepatoprotective effects of the drug.

CONCLUSION

The inclusion of remaxol, a drug with antihypoxic/antioxidant and hepatoprotective effects, in the nutritional rehabilitation regimen contributes to more effective medical rehabilitation of patients operated on for decompensated BPH. This ensures earlier correction of metabolic disorders and increases the body’s adaptive capacity, positively influencing the course of the postoperative period.