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Bril E.V.

Fedotova N.A.

Zimnyakova O.S.

Turgunhugaev O.E.

Yusupova M.M.

Yarkova I.G.

Diagnosis and treatment approaches for sialorrhea in patients with Parkinson’s disease

Authors:

Bril E.V., Fedotova N.A., Zimnyakova O.S., Turgunhugaev O.E., Yusupova M.M., Yarkova I.G.

More about the authors

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To cite this article:

Bril EV, Fedotova NA, Zimnyakova OS, Turgunhugaev OE, Yusupova MM, Yarkova IG. Diagnosis and treatment approaches for sialorrhea in patients with Parkinson’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(10):29‑34. (In Russ.)
https://doi.org/10.17116/jnevro202412410129

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References:

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  2. Kalf JG, de Swart BJ, Borm GF, et al. Prevalence and definition of drooling in Parkinson’s disease: a systematic review. J Neurol. 2009;256(9):1391-1396. https://doi.org/10.1007/s00415-009-5098-2
  3. Ou R, Guo X, Wei Q, et al. Prevalence and clinical correlates of drooling in Parkinson disease: a study on 518 Chinese patients. Park Relat Disord. 2015;21(3):211-215.  https://doi.org/10.1016/j.parkreldis.2014.12.004
  4. Politis M, Wu K, Molloy S, et al. Parkinson’s disease symptoms: the patient’s perspective. Mov Dis. 2010;25(11):1646-1651. https://doi.org/10.1002/mds.23135
  5. Kurushina OV, Derichenko OA, Ansarov KhSh. Experience in managing patients with sialorrhea in Parkinson’s disease. Bulletin of the National Parkinson’s Disease and Movement Disorder Society. 2023;1:12-15. (In Russ.). https://doi.org/10.24412/2226-079X-2023-12583
  6. Association European Parkinson’s Disease. Sialorrhea survey report. June 2021. Available at: https://www.parkinsonseurope.org/media/2832/epda-sialorrhea-survey-report.pdf
  7. Nóbrega AC, Rodrigues B, Melo A. Is silent aspiration a risk factor for respiratory infection in Parkinson’s disease patients? Park Relat Disord. 2008;14(8):646-648.  https://doi.org/10.1016/j.parkreldis.2007.12.007
  8. Panebianco M, Marchese-Ragona R, Masiero S, et al. Dysphagia in neurological diseases: a literature review. Neurol Sci. 2020;41:3067-3073. https://doi.org/10.1007/s10072-020-04495-2
  9. Miller N, Walshe M, Walker RW. Sialorrhea in Parkinson’s disease: prevalence, impact and management strategies. Res Rev Park. 2019;9:17-28.  https://doi.org/10.2147/JPRLS.S177409
  10. Jost WH, Friedman A, Michel O, et al. SIAXI: Placebo-controlled, randomized, double-blind study of incobotulinumtoxinA for sialorrhea. Neurology. 2019;92(17):e1982-e1991. https://doi.org/10.1212/WNL.0000000000007368
  11. Zaharov DV, Mihajlov MV. Sovremennye terapevticheskie strategii v korrekcii sialorei. Byulleten Nacionalnogo obshestva po izucheniyu bolezni Parkinsona i rasstrojstv dvizhenij. 2023;1:8-11. (In Russ.).
  12. Straka I, Minár M, Gažová A, et al. Clinical aspects of adherence to pharmacotherapy in Parkinson disease: A PRISMA-compliant systematic review. Medicine. 2018;97(23):e10962. https://doi.org/10.1097/MD.0000000000010962
  13. Akbar U, Dham B, He Y, et al. Incidence and mortality trends of aspiration pneumonia in Parkinson’s disease in the United States, 1979-2010. Park Relat Disord. 2015;21(9):1082-1086. https://doi.org/10.1016/j.parkreldis.2015.06.020
  14. Bergmans B, Clark V, Isaacson SH, et al. Recommendations for a paradigm shift in approach to increase the recognition and treatment of sialorrhea in Parkinson’s disease. Clin Park Relat Disord. 2023;9:100223. https://doi.org/10.1016/j.prdoa.2023.100223

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