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Ponomareva I.V.

Regional Clinical Hospital No. 3;
Center for Sleep Medicine

Stepanova S.B.

South Ural State Medical University

Reneva S.A.

Regional Treatment and Rehabilitation Center

Sorokova E.V.

Medical Center «Neurology»

Vagina M.A.

Sverdlovsk Regional Clinical Hospital

Makodzeba O.A.

Medical Center «Lotos»

Galiullin T.R.

Bashkir State Medical University

Possibilities of optimizing therapy in COVID-19 survivors with focal epilepsy

Authors:

Ponomareva I.V., Stepanova S.B., Reneva S.A., Sorokova E.V., Vagina M.A., Makodzeba O.A., Galiullin T.R.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2023;123(3): 130‑136

DOI: 10.17116/jnevro2023123031130

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Table of contents

POSSIBILITIES OF OPTIMIZING THERAPY IN COVID-19 SURVIVORS WITH FOCAL EPILEPSY
POSSIBILITIES OF OPTIMIZING THERAPY IN COVID-19 SURVIVORS WITH FOCAL EPILEPSY

To cite this article:

Ponomareva IV, Stepanova SB, Reneva SA, Sorokova EV, Vagina MA, Makodzeba OA, Galiullin TR. Possibilities of optimizing therapy in COVID-19 survivors with focal epilepsy. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;123(3):130‑136. (In Russ.)
https://doi.org/10.17116/jnevro2023123031130

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

To study the effect of phenosanoic acid therapy on the frequency of seizures, asthenia and quality of life of adult patients with focal epilepsy who had a new coronavirus infection caused by SARS-CoV-2.

MATERIAL AND METHODS

The data of 20 patients with focal epilepsy who suffered COVID-19 and received therapy with phenosanic acid (Dibufelon) were studied. The frequency of epileptic seizures, the severity of asthenia and the quality of life were evaluated according to clinical scales.

RESULTS

Significant decrease in the frequency of bilateral tonic-clonic seizures and focal seizures with loss of consciousness was recorded. There was a significant improvement in the quality of life. There was no significant dynamics of asthenia against the background of taking the drug phenosanic acid in patients.

CONCLUSION

The preparation of phenosanic acid can be an effective means of add-on therapy in patients with epilepsy who have undergone COVID-19.

Keywords:

epilepsy
COVID-19
phenosanic acid
efficacy
tolerability
frequency of bilateral tonic-clonic seizures
antiepileptic drugs
fatigue
quality of life

Authors:

Ponomareva I.V.

Regional Clinical Hospital No. 3;
Center for Sleep Medicine

Stepanova S.B.

South Ural State Medical University

Reneva S.A.

Regional Treatment and Rehabilitation Center

Sorokova E.V.

Medical Center «Neurology»

Vagina M.A.

Sverdlovsk Regional Clinical Hospital

Makodzeba O.A.

Medical Center «Lotos»

Galiullin T.R.

Bashkir State Medical University

Received:

30.01.2023

Accepted:

17.02.2023

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References:

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