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Lyukmanov R.Kh.

Research Center of Neurology

Rimkevichus A.A.

Research Center of Neurology

Gnedovskaya E.V.

Research Center of Neurology

Suponeva N.A.

Research Center of Neurology

Pharmacotherapy in post-stroke rehabilitation

Authors:

Lyukmanov R.Kh., Rimkevichus A.A., Gnedovskaya E.V., Suponeva N.A.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2022;122(6): 40‑47

DOI: 10.17116/jnevro202212206140

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To cite this article:

Lyukmanov RKh, Rimkevichus AA, Gnedovskaya EV, Suponeva NA. Pharmacotherapy in post-stroke rehabilitation. S.S. Korsakov Journal of Neurology and Psychiatry. 2022;122(6):40‑47. (In Russ.)
https://doi.org/10.17116/jnevro202212206140

 
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The article presents data on the conditions of use and efficacy of botulinum toxin preparations, oral muscle relaxants, selective serotonin reuptake inhibitors, acetylcholinesterase inhibitors and a glutamatergic transmission modulator in post-stroke neurorehabilitation, and provides recommendations for their rational and safe use. The clinical efficacy of Mexidol, which has a polymodal effect on a wide range of post-stroke disorders, especially in long-term sequential therapy, is discussed. A complex use of post-stroke rehabilitation methods with the determination of individual tactics based on the clinical picture of the patient and the defined rehabilitation goals is recommended. The inclusion of Mexidol in the complex therapy of patients with stroke consequences for tasks related to improving motor, affective and cognitive functions and self-care and quality of life looks promising. It is necessary to continue high-quality clinical studies to assess the pharmaceuticals efficacy in relation to post-stroke disorders.

Keywords:

stroke
hemiparesis
spasticity
depression
dementia
neurorehabilitation
pharmacotherapy

Authors:

Lyukmanov R.Kh.

Research Center of Neurology

Rimkevichus A.A.

Research Center of Neurology

Gnedovskaya E.V.

Research Center of Neurology

Suponeva N.A.

Research Center of Neurology

Received:

11.05.2022

Accepted:

16.05.2022

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