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Kropacheva E.S.

Chazov National Medical Research Center of Cardiology

Dashaeva M.I.

Chazov National Medical Research Center of Cardiology

Panchenko E.P.

Chazov National Medical Research Center of Cardiology

Frailty in patients with atrial fibrillation: diagnosis, management, prevention and influence on prognosis

Authors:

Kropacheva E.S., Dashaeva M.I., Panchenko E.P.

More about the authors

Journal: Russian Cardiology Bulletin. 2025;20(1): 5‑12

DOI: 10.17116/Cardiobulletin2025200115

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Table of contents

FRAILTY IN PATIENTS WITH ATRIAL FIBRILLATION: DIAGNOSIS, MANAGEMENT, PREVENTION AND INFLUENCE ON PROGNOSIS
FRAILTY IN PATIENTS WITH ATRIAL FIBRILLATION: DIAGNOSIS, MANAGEMENT, PREVENTION AND INFLUENCE ON PROGNOSIS

To cite this article:

Kropacheva ES, Dashaeva MI, Panchenko EP. Frailty in patients with atrial fibrillation: diagnosis, management, prevention and influence on prognosis. Russian Cardiology Bulletin. 2025;20(1):5‑12. (In Russ.)
https://doi.org/10.17116/Cardiobulletin2025200115

Подписка 2025-2 (Russian Cardiology Bulletin)
 
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The review is devoted to frailty in patients with atrial fibrillation (AF). The number of elderly patients with AF is constantly increasing, and this category of patients is characterized by high incidence of stroke and bleeding. Frailty is a key geriatric syndrome. Research of frailty in patients with AF is extremely important, since involutional processes in cardiovascular system, brain, kidneys and gastrointestinal tract cause metabolism of anticoagulants and increase the risk of thromboembolic and hemorrhagic complications. The review highlights the tools, scales and questionnaires for assessing frailty in patients with cardiovascular diseases. In addition, some biomarkers related to frailty syndromes in patients with AF are described. Data on negative impact of frailty on prognosis in patients with AF are presented, and measures to prevent frailty and its progression are outlined. These data indicate the need to introduce geriatric tools into interdisciplinary approach. This can delay loss of working capacity, improve the quality of life and prevent negative outcomes in elderly and senile patients with AF.

Keywords:

atrial fibrillation
frailty
anticoagulants
elderly
stroke
bleeding

Authors:

Kropacheva E.S.

Chazov National Medical Research Center of Cardiology

Dashaeva M.I.

Chazov National Medical Research Center of Cardiology

Panchenko E.P.

Chazov National Medical Research Center of Cardiology

Received:

06.12.2024

Accepted:

21.12.2024

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