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Sinkin M.V.

Sklifosovsky Research Institute for Emergency Care

Talypov A.E.

Sklifosovsky Research Institute of Emergenscy Medicine

Yakovlev A.A.

Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences;
Soloviev Scientific and Practical Psychoneurological Center

Kordonskaya O.O.

Sklifosovsky Research Institute of Emergenscy Medicine;
Federal Center of Brain and Neurotechnology

Teplyshova A.M.

Research Center of Neurology

Trifonov I.S.

Evdokimov Moscow State University of Medical Dentistry

Guekht A.B.

Moscow Research and Clinical Centre for Neuropsychiatry;
Pirogov Russian National Research Medical University

Krylov V.V.

A.I. Evdokimov Moscow State Medical University;
N.V. Sklifosovsky Scientific and Research Institute of Emergency Medicine

Long-term EEG monitoring in patients with acute traumatic brain injury

Authors:

Sinkin M.V., Talypov A.E., Yakovlev A.A., Kordonskaya O.O., Teplyshova A.M., Trifonov I.S., Guekht A.B., Krylov V.V.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(5): 62‑67

DOI: 10.17116/jnevro202112105162

Views: 2011

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Table of contents

LONG-TERM EEG MONITORING IN PATIENTS WITH ACUTE TRAUMATIC BRAIN INJURY
LONG-TERM EEG MONITORING IN PATIENTS WITH ACUTE TRAUMATIC BRAIN INJURY

To cite this article:

Sinkin MV, Talypov AE, Yakovlev AA, et al. . Long-term EEG monitoring in patients with acute traumatic brain injury. S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(5):62‑67. (In Russ.)
https://doi.org/10.17116/jnevro202112105162

Подписка 2025-2 (S.S. Korsakov Journal of Neurology and Psychiatry)
 
МСФ на ЯМ
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OBJECTIVE

To investigate the informativeness of long-term scalp EEG monitoring in patients with acute traumatic brain injury (TBI).

MATERIAL AND METHODS

The informativity of long-term EEG monitoring (LTM) was performed in 60 patients with acute severe TBI. Odd ratios (OR) of unfavorable outcome and non-convulsive status epilepticus (NCSE) among clinical, neurophysiological and radiological features were calculated.

RESULTS

EEG features of the unfavorable outcome are: slowing of the dominant background rhythm below q range (OR 3.5, CI 1.2-10.7), absence of frontal-occipital gradient (OR 10.2, CI 1.89-10.12), absence of reactivity (OR 8.75, CI 2.14-35.7), absence of variability (OR 6.25, CI 1.72-22.6) and absence of NREM sleep, stage 2 (OR 5.8, CI 1.79-18.91). Clinical features associated with the unfavorable outcome are: a decrease in GCS score (OR 1.25, CI 1.07-1.47), TBI severity (OR 2.46, CI 1.16-5.18), axial dislocation (OR 4.45, CI 1.08-18.29). ORs for NCSE are significant for the following EEG features: presence of rhythmic and periodic patterns (RPP) (OR 11.92, CI 1.37-103.39), stimulus induced RPP (OR 23.14, CI 2.56-209.34), “plus” modifier (OR 4.11, CI 1.13-14.91) and electrographic evolution (OR 13.05, CI 3.59-47.39). Background rhythm slowing below q range reduces NCSE probability (OR 3.33, CI 1.09-10).

CONCLUSION

Long-term EEG monitoring is an informative tool for prognosis of outcome and diagnosis of NCSE in patients with severe TBI. The risk of NCSE increases with Marshall score but NCSE is not associated with poor outcome that requires an individual selection of intensive care.

Keywords:

traumatic brain injury
electroencephalography
EEG monitoring
non-convulsive status epilepticus
epileptic seizures
TBI prognosis

Authors:

Sinkin M.V.

Sklifosovsky Research Institute for Emergency Care

Talypov A.E.

Sklifosovsky Research Institute of Emergenscy Medicine

Yakovlev A.A.

Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences;
Soloviev Scientific and Practical Psychoneurological Center

Kordonskaya O.O.

Sklifosovsky Research Institute of Emergenscy Medicine;
Federal Center of Brain and Neurotechnology

Teplyshova A.M.

Research Center of Neurology

Trifonov I.S.

Evdokimov Moscow State University of Medical Dentistry

Guekht A.B.

Moscow Research and Clinical Centre for Neuropsychiatry;
Pirogov Russian National Research Medical University

Krylov V.V.

A.I. Evdokimov Moscow State Medical University;
N.V. Sklifosovsky Scientific and Research Institute of Emergency Medicine

Received:

28.05.2020

Accepted:

23.07.2020

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