The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Ulyankin V.E.

Privolzhsky Research Medical University;
National Research Ogarev Mordovia State University

Machinsky P.A.

National Research Ogarev Mordovia State University

Vorobiev V.G.

Privolzhsky Research Medical University;
Nizhny Novgorod Regional Bureau of Forensic Medical Expertise

Edelev I.S.

Privolzhsky Research Medical University;
Nizhny Novgorod Regional Bureau of Forensic Medical Expertise

Edelev N.S.

Privolzhsky Research Medical University;
Nizhny Novgorod Regional Bureau of Forensic Medical Expertise

Main mechanisms of secondary ischemic brain damage formation in case of craniocerebral injury

Authors:

Ulyankin V.E., Machinsky P.A., Vorobiev V.G., Edelev I.S., Edelev N.S.

More about the authors

Journal: Forensic Medical Expertise. 2024;67(3): 54‑59

DOI: 10.17116/sudmed20246703154

Read: 1541 times

Download PDF (RU)
Contact the author
Table of contents

MAIN MECHANISMS OF SECONDARY ISCHEMIC BRAIN DAMAGE FORMATION IN CASE OF CRANIOCEREBRAL INJURY
MAIN MECHANISMS OF SECONDARY ISCHEMIC BRAIN DAMAGE FORMATION IN CASE OF CRANIOCEREBRAL INJURY

To cite this article:

Ulyankin VE, Machinsky PA, Vorobiev VG, Edelev IS, Edelev NS. Main mechanisms of secondary ischemic brain damage formation in case of craniocerebral injury. Forensic Medical Expertise. 2024;67(3):54‑59. (In Russ.)
https://doi.org/10.17116/sudmed20246703154

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Dete­rmination of formation age of acute traumatic intracranial subdural hema­tomas using computed tomo­graphy. Fore­nsic Medi­cal Expe­rtise. 2025;(1):17-21
On the challenges and shortfalls of expert asse­ssment of maxi­llofacial inju­ries with concussions acco­rding to medi­cal docu­ments only. Fore­nsic Medi­cal Expe­rtise. 2025;(1):54-58
Glial fibrillary acidic protein: is there a rela­tionship with the course of multiple scle­rosis and traumatic brain injury before the onset of multiple scle­rosis?. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(10):80-84
Risk factors of unfa­vorable outcome after deco­mpressive craniectomy in children with severe traumatic brain injury. Burdenko's Journal of Neurosurgery. 2025;(3):42-47
Reorganization of the corticospinal tract and thalamocortical projections in children with sequelae of severe traumatic brain injury. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(5):56-61
Effi­cacy of Reco­gnan in the therapy of neurological diso­rders after traumatic brain injury. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(7):41-45
Predictors of adve­rse outcomes after severe traumatic brain injury. Burdenko's Journal of Neurosurgery. 2025;(5):71-78
Model for predicting mortality in patients with traumatic brain injury. Russian Journal of Anesthesiology and Reanimatology. 2025;(5):66-73
Abstract:

OBJECTIVE

To systematize the mechanisms of formation and morphology of secondary ischemic brain damage, formed in the case of craniocerebral injury.

MATERIAL AND METHODS

A literature review devoted to the study of formation mechanisms of secondary ischemic brain damage in craniocerebral injury was conducted. The secondary sequential and secondary long-term ischemic brain damage in the posttraumatic period, as well as intracranial and extracranial factors that contribute to their occurrence and progression, were considered.

RESULTS AND CONCLUSION

Analysis of the literature has shown that primary lesions occurring at the time of head injury must be differentiated from sequential and long-term secondary ischemic changes in different brain structures.

Keywords:

craniocerebral injury
secondary ischemic brain damage

Authors:

Ulyankin V.E.

Privolzhsky Research Medical University;
National Research Ogarev Mordovia State University

Machinsky P.A.

National Research Ogarev Mordovia State University

Vorobiev V.G.

Privolzhsky Research Medical University;
Nizhny Novgorod Regional Bureau of Forensic Medical Expertise

Edelev I.S.

Privolzhsky Research Medical University;
Nizhny Novgorod Regional Bureau of Forensic Medical Expertise

Edelev N.S.

Privolzhsky Research Medical University;
Nizhny Novgorod Regional Bureau of Forensic Medical Expertise

Received:

13.07.2023

Accepted:

01.09.2023

Close metadata

References:

  1. Puras UV, Talypov AE, Petrikov SS, Krylov VV. Factors of secondary ischemic cerebral damage at craniocerebral trauma part 1. Intracranial and extracranial factors of secondary cerebral damage. Russian Sklifosovsky journal of emergency medical care. 2012;1:56-65. (In Russ.).
  2. Puras UV, Talypov AE, Petrikov SS, Krylov VV. Factors of secondary ischemic cerebral damage at craniocerebral trauma part 2. Guidelines for correction of the secondary cerebral damage factors. Russian Sklifosovsky journal of emergency medical care. 2012;2:59-65. (In Russ.).
  3. Potapov AA, Likhterman LB, Kravchuk AD, Kornienko VN, Zakharova NE, Oshorov AV, Filatova MM. Modern approaches to the management of traumatic brain injury. Annals of Clinical and Experimental Neurology. 2010;4(1):4-12. (In Russ.).
  4. Shashkin ChS. Relevance of clinical and forensic issues of traumatic brain injury. Neurosurgery and neurology of Kazakhstan. 2010;21(4):45-47. (In Russ.).
  5. Popov VL. Forensic medical assessment of the role of the injury and pathology in the development of basal subarachnoidal hemorrhage. Sudebno-Meditsinskaya Ekspertisa. 2013;56(3):12-17. (In Russ.).
  6. Avdeev MI. Sudebno-meditsinskaya ekspertiza trupa. M.: Meditsina; 1976. (In Russ.).
  7. Singur NA. Ushiby mozga (mekhanizmy vozniknoveniya, patologicheskaya anatomiya, sudebno-meditsinskaya diagnostika). M.: Meditsina; 1970. (In Russ.).
  8. Koludarova EM, Tuchik ES. Methodology for forensic diagnosis of diffuse axonal injury. Sudebno-Meditsinskaya Ekspertisa. 2022;65(1):14-19. (In Russ.). https://doi.org/10.17116/sudmed20226501114
  9. Zadvornov AA, Golomidov AV, Grigoriev EV. Clinical pathophysiology of cerebral edema (part 1). Messenger of Anesthesiology and Resuscitation. 2017;14(3):44-50. (In Russ.). https://doi.org/10.21292/2078-5658-2017-14-3-44-50
  10. Zadvornov AA, Golomidov AV, Grigoriev EV. Clinical pathophysiology of cerebral edema (part 2). Messenger of Anesthesiology and Resuscitation. 2017;14(4):52-60. (In Russ.). https://doi.org/10.21292/2078-5658-2017-14-4-52-60
  11. Karmen NB, Moroz VV, Mayevsky EI. Mechanisms of secondary neuronal damage in severe brain injury (part 1). General reanimatology. 2011;7(4):56-59. (In Russ.).
  12. Moroz VV, Karmen NB, Mayevsky EI. Mechanisms of secondary neuronal damage in severe brain injury (part 2). General reanimatology. 2011;7(5):44-47. (In Russ.).
  13. Krylov VV, Puras UV. Pathophysiologic mechanisms of the secondary brain damage after craniocerebral trauma. The Neurological Journal. 2013;18(4):4-7. (In Russ.).
  14. Karpunin AY, Petrikov SS, Khamidova LT, Krylov VV. Effect of cerebral vasospasm on disease outcomes in patients with severe traumatic brain injury. Russian Sklifosovsky journal of emergency medical care. 2016;3:49-54. (In Russ.).
  15. Karpunin AY, Petrikov SS, Krylov VV. Cerebral vasospasm in patients with severe traumatic brain injury. The Neurological Journal. 2015;20(1):42-48. (In Russ.).
  16. Kuzibaev ZhM, Makhkamov KE. Possibilities of computed tomography in the diagnosis of secondary ischemic brain damage in traumatic intracranial hemorrhages. The bulletin of emergency medicine. 2016;1:45-47. (In Russ.).
  17. Fraerman AP. Traumatic brain compression: modern aspects of the problem, management. Modern technologies in medicine. 2011;4:146-150. (In Russ.).
  18. Skoromets TA. Vtorichnaya ishemiya golovnogo mozga v ostrom periode cherepno-mozgovoi travmy: Dis. ... d-ra. med. nauk. SPb. 2002. (In Russ.).
  19. Bolyukh AS. Post-traumatic cerebral vasospasm. Ukrainian Neurosurgical Journal. 2000;2:15-21. (In Russ.).
  20. Puras YuV, Kordonsky AYu, Talypov AE. Mechanisms of brain contusion foci progression. The Russian journal of neurosurgery. 2013;4:91-96. (In Russ.).
  21. Byvaltsev VA. Cherepno-mozgovaya travma: uchebnoe posobie. Irkutsk State Medical University Minzdrava Rossii, Kafedra neirokhirurgii i innovatsionnoi meditsiny. Irkutsk: IGMU; 2018. (In Russ.).
  22. Bumai AO. Modern problems of diagnostics and tactics of surgical treatment of patients with multifocal brain injuries in concomitant traumatic brain injury. Bulletin of Siberian medicine. 2008;7(5-2):310-317. (In Russ.).
  23. Pigolkin YuI, Leonov SV, Dubrovin IA, Gornostaev DV. Cherepno-mozgovaya travma. Mekhanogenez, morfologiya i sudebno-meditsinskaya otsenka: prakticheskoe posobie. M.: Izdatel’stvo Yurait; 2023. (In Russ.).
  24. Semchenko VV, Shcherbakov PN, Stepanov SS, Voinov AYu, Khizhnyak AS. Structural and functional characteristics of the perifocal zone of the cerebral cortex in the acute period of traumatic brain injury. General reanimatology. 2005;1(1):29-33. (In Russ.).
  25. Makhkamov KE, Kuzibaev ZhM. Surgical correction of secondary brain injuries in patients with intracranial hemorrhages. The bulletin of emergency medicine. 2013;2:104-107. (In Russ.).
  26. Kuzibaev ZhM, Makhkamov KE. Secondary cerebral ischemia in the postoperative period with acute subdural hematomas. The bulletin of emergency medicine. 2015;4:43-46. (In Russ.).
  27. Vasilyeva YB, Talypov AE, Petrikov SS. Clinical features of traumatic brain injury in various kinds of brain damage. Russian Sklifosovsky journal of emergency medical care. 2019;8(3):295-301. (In Russ.). https://doi.org/10.23934/2223-9022-2019-8-3-295-301
  28. Popov VL. Cherepno-mozgovaya travma: Sudebno-meditsinskie aspekty. L.: Meditsina; 1988. (In Russ.).
  29. Midori IM, Bersnev VP, Ryabukha NP. Syndrome of brain compression in cranio-cerebral trauma. Grekov’s bulletin of surgery. 2012;171(6):66-68. (In Russ.).
  30. Krylov VV. Lektsii po cherepno-mozgovoi travme: Uchebnoe posobie. M.: Meditsina; 2010. (In Russ.).
  31. Dzenis YuL, Sverzickis RJ, Dolgopolova JD. Dislocation syndrome and brainstem herniation (review and first experience surgical treatment for nontraumatical intracerebral haematomas in large hemispheres). Meditsinskie novosti. 2020;7(310):30-38. (In Russ.).
  32. Kadyrov RM, Mamytov MM. Characterization of the clinical course and analysis of the dependence of the outcomes of dislocation syndrome in patients with focal brain lesions. Neurosurgery and neurology of Kazakhstan. 2012;4(29):21-25. (In Russ.).
  33. Puras JV. The estimation of acute dislocation syndrome severity at patients with head injury. Russian journal of neurosurgery. 2014;1:34-40. (In Russ.).
  34. Klimash AV, Kondakov EN. The characteristics of dislocation syndrome in the case of supratentorial compression of brain at patients with severe head injury (part 1). Russian journal of neurosurgery. 2015;3:3-10. (In Russ.).
  35. Klimash AV, Kondakov EN. The characteristics of dislocation syndrome in the case of supratentorial compression of brain at patients with severe head injury (part 2). Russian journal of neurosurgery. 2015;4:13-16. (In Russ.).
  36. Greben’kov AB. Sudebno-meditsinskaya ekspertiza cherepno-mozgovoi travmy: spravochnoinformatsionnye materialy. Kursk: OBUZ «Byuro SME»; 2014. (In Russ.).
  37. Kozyrev KM. Some pathomorphological regularities of acute cerebrum swelling syndrome progression and death mechanism at it. Journal of new medical technologies. 2012;19(1):138-143. (In Russ.).
  38. Petrikov SS, Krylov VV. Secondary brain damage in patients with intracranial hemorrhages. Annals of clinical and experimental neurology. 2011;1:44-51. (In Russ.).
  39. Machinskiy PA, Rybakov AG, Ulyankin VE, Kadyrov ASH, Loshkarev IA. Collateral blood supply of the brain. Modern Problems of Science and Education. 2021;4:98. (In Russ.). https://doi.org/10.17513/spno.30995
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.