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Esin R.G.

Kazan State Medical Academy — Branch of the Russian Medical Academy of Continuing Professional Education;
Kazan (Volga Region) Federal University

Safina D.R.

Kazan Federal University

Khakimova A.R.

Kazan State Medical Academy

Esin O.R.

Kazan (Volga region) Federal University;
Clinic of Otorhinolaryngology

Neuroinflammation and neuropathology

Authors:

Esin R.G., Safina D.R., Khakimova A.R., Esin O.R.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(4): 107‑112

DOI: 10.17116/jnevro2021121041107

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Table of contents

NEUROINFLAMMATION AND NEUROPATHOLOGY
NEUROINFLAMMATION AND NEUROPATHOLOGY

To cite this article:

Esin RG, Safina DR, Khakimova AR, Esin OR. Neuroinflammation and neuropathology. S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(4):107‑112. (In Russ.)
https://doi.org/10.17116/jnevro2021121041107

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The review highlights the current understanding of the role of autoimmune neuroinflammation in the pathogenesis of vascular, neurodegenerative and other diseases of the nervous system. The mechanisms of the response of the resident cells of the central nervous system (microglia, astrocytes) and peripheral cells of the immune system are considered. Possible therapeutic potential of phosphodiesterase inhibitors, which have antiplatelet properties and the ability to suppress autoimmune inflammation, are outlined. The authors consider dipyridamole, an inhibitor of phosphodiesterase, as a promising drug.

Keywords:

neuroinflammation
microglia
astrocytes
blood-brain barrier
dipyridamole

Authors:

Esin R.G.

Kazan State Medical Academy — Branch of the Russian Medical Academy of Continuing Professional Education;
Kazan (Volga Region) Federal University

Safina D.R.

Kazan Federal University

Khakimova A.R.

Kazan State Medical Academy

Esin O.R.

Kazan (Volga region) Federal University;
Clinic of Otorhinolaryngology

Received:

16.11.2020

Accepted:

18.01.2021

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References:

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