Cerebrovascular complications in patients with malignant neoplasms

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Patients with malignant neoplasms have an increased risk of cerebrovascular complications (intratumoral hemorrhage, invasion of arterial and venous sinus by tumor mass or leptomeningeal infiltrates, and tumor embolism). The review discusses the role and importance of cisplatin and radiation therapy in the occurrence of cerebrovascular complications in patients with malignant neoplasms that may occur before, during or years after treatment. Descriptions of individual clinical observations of the lesions of the central nervous system in the treatment of cancer are provided. The type and mechanism of stroke, as well as the stage and pathology of the neoplasm, dictate the use of a multidisciplinary approach, which ensures proper management and helps to outline the prognosis in this category of patients.

Keywords:

stroke

endothelium

malignant neoplasms

cisplatin

radiation therapy

Authors:

Murkamilov I.T.

I.K. Akhunbaev Kyrgyz State Medical Academy;
Kyrgyz-Russian Slavic University named after the First President of Russian Federation B.N. Yeltsin

ORCID: 0000-0001-8513-9279

Sabirov I.S.

Kyrgyz-Russian Slavic University named after the First President of Russian Federation B.N. Yeltsin

ORCID: 0000-0002-8387-5800

Fomin V.V.

Sechenov University

ORCID: 0000-0002-2682-4417

Kudaibergenova I.O.

Kyrgyz State Medical Academy named after I.K. Akhunbaev

Yusupov F.A.

Osh State University

ORCID: 0000-0003-0632-6653

Schastlivenko A.I.

Vitebsk State Order of Peoples Friendship Medical University

Murkamilova Zh.A.

Kyrgyz-Russian Slavic University

Received:

28.05.2020

Accepted:

02.06.2020

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