Cognitive impairment in patients with comorbid recurrent affective and panic disorders

Tsygankov B.D.; Pastukh I.A.

doi:https://doi.org/10.17116/jnevro202012007123

Tsygankov B.D.

Evdokimov Moscow State University of Medicine and Dentistry

Pastukh I.A.

Kursk State Medical University

Cognitive impairment in patients with comorbid recurrent affective and panic disorders

Authors:

Tsygankov B.D., Pastukh I.A.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(7): 23‑28

DOI: 10.17116/jnevro202012007123

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To cite this article:

Tsygankov BD, Pastukh IA. Cognitive impairment in patients with comorbid recurrent affective and panic disorders. S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(7):23‑28. (In Russ.)
https://doi.org/10.17116/jnevro202012007123

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

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Abstract:

OBJECTIVE

To designate the targets for medical and psychotherapeutic effects in patients with comorbid recurrent affective and panic disorders based on the study of cognitive functions.

MATERIAL AND METHODS

A battery of pathopsychological tests («Schulte Table», «Corrective Test», «Ten Words test», «Cube Drawing Technique», Binet and Berstein Tests) has been used to assess the neuro-cognitive status of 60 patients with symptoms of recurrent affective (depressive) and panic disorders. According to ICD-10, 27 patients have been diagnosed with recurrent affective disorder with a mild or moderate depressive episode (RAD, F33.0, F33.1) in combination with panic disorder (PD, F41.0). The control group included 33 patients with recurrent affective disorder with a mild to moderate depressive episode (RAD, F33.0, F33.1) without panic disorder.

RESULTS

All the patients showed the changes in the cognitive sphere. In patients with recurrent affective disorder in combination with panic disorder, cognitive impairment was more pronounced than that in patients from the control group. Cognitive functions in patients with recurrent affective and comorbid panic disorder were distinguished by their peculiarity, which manifested itself in «left hemisphere» disorders in the form of paroxysmal emotional disorders with the predominance of fear and anxiety affect, work dysfunction in a number of neuropsychological factors: successiveness, spatial, inertness-mobility, for which mediobasal and subcortical parts of the brain are responsible. The targets for medical and psychotherapeutic effects in patients with comorbid panic and recurrent depressive disorder are: attention, auditory and verbal memory, thinking components (logical and spatial).

CONCLUSION

It is reasonable to use neuropsychological correction of cognitive impairment in this group of patients.

Keywords:

recurrent affective disorder

panic disorder

comorbidity

neuropsychological and pathopsychological methods of investigation

cognitive processes

Authors:

Tsygankov B.D.

Evdokimov Moscow State University of Medicine and Dentistry

Pastukh I.A.

Kursk State Medical University

Received:

09.02.2020

Accepted:

26.02.2020

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References:

Hirschfeld RMA. The comorbidity of major depression and anxiety disorders: Recognition and management in primary care. J Clin Psychiatry. 2001;3(6):244-254. https://doi.org/10.4088/pcc.v03n0609
Rakitskaya NYu. The evolution of diagnostic and therapeutic approaches to anxiety and depressive disorders. Sibirskij Vestnik Psihiatrii i Narkologii. 2009;3(54):88-92. (In Russ.).
Gorbunova AA, Koliutskaia EV. Panic disorder and affective pathology (comorbidity aspects). Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova. 2014;114(10):9-13. (In Russ.).
Korabelnikova EA. A modern approach to the diagnosis and therapy of panic disorder. Poliklinika. Revmatologiya/Nevrologiya (spec. vypusk). 2016;2:31-36. (In Russ.).
Pogosova IA. Clinical peculiarities of panic disorders, combined with psychic and narcological pathology. Nevrologicheskij vestnik. Zhurnal im. V.M. Bextereva. 2012;3:42-47. (In Russ.).
Restivo MR, McKinnon MC, Frey BN, Hall GB, Taylor VH. Effect of obesity on cognition in adults with and without a mood disorder: study design and methods. BMJ Open. 2016;6(2). https://doi.org/10.1136/bmjopen-2015-009347
Papakostas GI, Culpepper L. Understanding and managing cognition in the depressed patient. J Clin Psychiatry. 2015;76(4):418-425. https://doi.org/10.4088/JCP.13086ah1c
Chepelyuk AA, Vinogradova MG, Kovalenok TV, Dorofeeva OA, Metlina MV, Neznamov GG. Cognitive processes in patients with different structure of anxiety disorders. Zhurnal Nevrologii i Psihiatrii im. S.S. Korsakova. 2018;118(3):4-9. (In Russ.). https://doi.org/10.17116/jnevro2018118314-9
Gordeev SA, Posohov SI, Covrov GV, Katenko SV. Psychophysiological specific of panic attack and generalized anxiety disorder. Zhurnal Nevrologii i Psihiatrii im. S.S. Korsakova. 2013;113(5):11-14. https://doi.org/10.1001/archpsyc.62.6.617
Yanushko MG, Shamanina MV, Ivanov MV. Cognitive functioning parameters in patients with recurrent depressive disorder. Sotsialnaia i Klinicheskaia Psikhiatriia. 201;27(3):27-31. (In Russ.).
Tsarenko DM. Clinical and psychopathological features of cognitive impairment in disorders of the anxiety-depressive spectrum. Moskovskii Nauchno-Issledovatel’skii Institut Psikhiatrii. 2012:5:3-19. (In Russ.).
Semke VYa, Pogosova IA. Psychotherapy of comorbidity (combination) phobic-anxiety and affective disorders. Sibirskij Vestnik Psihiatrii i Narkologii. 2010;5(62):50-75. (In Russ.).
Tsygankov BD, Yaltonskaia AV. Group cognitive-behavioral psychotherapy in the treatment of depressive disorders. Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova. 2012;112(10):68-74. (In Russ.).