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Gusev E.I.
Pirogov National Research Medical University
Martynov M.U.
Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnology of the Federal Medical Biological Agency
Boyko A.N.
Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency
Voznyuk I.A.
Latsh N.Yu.
Pirogov National Research Medical University
Spirin N.N.
Yaroslavl State Medical University
Shamalov N.A.
Pirogov National Research Medical University;
Federal Center for Brain Research and Neurotechnologies
Novel coronavirus infection (COVID-19) and nervous system involvement: pathogenesis, clinical manifestations, organization of neurological care
Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(6): 7‑16
Views: 21939
Downloaded: 1226
To cite this article:
Gusev EI, Martynov MU, Boyko AN, et al. . Novel coronavirus infection (COVID-19) and nervous system involvement: pathogenesis, clinical manifestations, organization of neurological care. S.S. Korsakov Journal of Neurology and Psychiatry.
2020;120(6):7‑16. (In Russ.)
https://doi.org/10.17116/jnevro20201200617
Novel coronavirus SARS-CoV-2 and COVID-19, besides affecting the respiratory system, may lead to central and peripheral nervous system disorders and also cause muscular symptoms. The authors review the literature and own clinical case with respect to nervous system involvement in COVID-19 patients. There is a correlation between the severity of COVID-19 and the severity and frequency of neurologic complications. Severe neurologic symptoms are primarily observed in patients with severe COVID-19. Neurologic-associated symptoms may include stroke, acute necrotizing encephalopathy, and Guillen—Barre syndrome. Diseases that potentially aggravate COVID-19 and increase the risk of neurologic complications include arterial hypertension, diabetes, chronic diseases of the heart and respiratory system. The probable impact of human coronaviruses on chronic and progressive diseases of the nervous system with particular respect to multiple sclerosis is reviewed. A triage plan for stroke and MS patients during the COVID-19 pandemic, depending on the risk of coronavirus infection, is presented.
Keywords:
Authors:
Gusev E.I.
Pirogov National Research Medical University
Martynov M.U.
Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnology of the Federal Medical Biological Agency
Boyko A.N.
Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency
Voznyuk I.A.
Latsh N.Yu.
Pirogov National Research Medical University
Spirin N.N.
Yaroslavl State Medical University
Shamalov N.A.
Pirogov National Research Medical University;
Federal Center for Brain Research and Neurotechnologies
Received:
21.04.2020
Accepted:
30.04.2020
List of references:
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