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Gusev E.I.

Pirogov National Research Medical University

Martynov M.Yu.

Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnology of the Federal Medical Biological Agency

Boyko A.N.

Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency

Voznyuk I.A.

Latsh N.Yu.

Pirogov National Research Medical University

Sivertseva S.A.

Medical and Sanitary unit «Neftyanik»

Spirin N.N.

Yaroslavl State Medical University

Shamalov N.A.

Pirogov National Research Medical University;
Federal Center for Brain Research and Neurotechnologies

Novel coronavirus infection (COVID-19) and nervous system involvement: pathogenesis, clinical manifestations, organization of neurological care

Authors:

Gusev E.I., Martynov M.Yu., Boyko A.N., Voznyuk I.A., Latsh N.Yu., Sivertseva S.A., Spirin N.N., Shamalov N.A.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(6): 7‑16

DOI: 10.17116/jnevro20201200617

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Table of contents

NOVEL CORONAVIRUS INFECTION (COVID-19) AND NERVOUS SYSTEM INVOLVEMENT: PATHOGENESIS, CLINICAL MANIFESTATIONS, ORGANIZATION OF NEUROLOGICAL CARE
NOVEL CORONAVIRUS INFECTION (COVID-19) AND NERVOUS SYSTEM INVOLVEMENT: PATHOGENESIS, CLINICAL MANIFESTATIONS, ORGANIZATION OF NEUROLOGICAL CARE

To cite this article:

Gusev EI, Martynov MYu, Boyko AN, et al. Novel coronavirus infection (COVID-19) and nervous system involvement: pathogenesis, clinical manifestations, organization of neurological care. S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(6):7‑16. (In Russ.)
https://doi.org/10.17116/jnevro20201200617

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
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Abstract:

Novel coronavirus SARS-CoV-2 and COVID-19, besides affecting the respiratory system, may lead to central and peripheral nervous system disorders and also cause muscular symptoms. The authors review the literature and own clinical case with respect to nervous system involvement in COVID-19 patients. There is a correlation between the severity of COVID-19 and the severity and frequency of neurologic complications. Severe neurologic symptoms are primarily observed in patients with severe COVID-19. Neurologic-associated symptoms may include stroke, acute necrotizing encephalopathy, and Guillen—Barre syndrome. Diseases that potentially aggravate COVID-19 and increase the risk of neurologic complications include arterial hypertension, diabetes, chronic diseases of the heart and respiratory system. The probable impact of human coronaviruses on chronic and progressive diseases of the nervous system with particular respect to multiple sclerosis is reviewed. A triage plan for stroke and MS patients during the COVID-19 pandemic, depending on the risk of coronavirus infection, is presented.

Keywords:

COVID-19
SARS-CoV-2
coronaviruses
nervous system
muscular system
stroke
multiple sclerosis
acute necrotizing encephalopathy
Guillen-Barre syndrome

Authors:

Gusev E.I.

Pirogov National Research Medical University

Martynov M.Yu.

Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnology of the Federal Medical Biological Agency

Boyko A.N.

Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency

Voznyuk I.A.

Latsh N.Yu.

Pirogov National Research Medical University

Sivertseva S.A.

Medical and Sanitary unit «Neftyanik»

Spirin N.N.

Yaroslavl State Medical University

Shamalov N.A.

Pirogov National Research Medical University;
Federal Center for Brain Research and Neurotechnologies

Received:

21.04.2020

Accepted:

30.04.2020

Close metadata

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