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Losenkov I.S.

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences

Plotnikov E.V.

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences

Epimakhova E.V.

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences

Bokhan N.A.

Mental Health Research Institute of the Tomsk National Research Medical Center of the Russian Academy of Science

Lithium in the psychopharmacology of affective disorders and mechanisms of its effects on cellular physiology

Authors:

Losenkov I.S., Plotnikov E.V., Epimakhova E.V., Bokhan N.A.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(11): 108‑115

DOI: 10.17116/jnevro2020120111108

Read: 50913 times

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Table of contents

LITHIUM IN THE PSYCHOPHARMACOLOGY OF AFFECTIVE DISORDERS AND MECHANISMS OF ITS EFFECTS ON CELLULAR PHYSIOLOGY
LITHIUM IN THE PSYCHOPHARMACOLOGY OF AFFECTIVE DISORDERS AND MECHANISMS OF ITS EFFECTS ON CELLULAR PHYSIOLOGY

To cite this article:

Losenkov IS, Plotnikov EV, Epimakhova EV, Bokhan NA. Lithium in the psychopharmacology of affective disorders and mechanisms of its effects on cellular physiology. S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(11):108‑115. (In Russ.)
https://doi.org/10.17116/jnevro2020120111108

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

However, despite successful use of lithium in the treatment of affective disorders for almost 40 years, the mechanisms of its therapeutic action are still poorly understood. This review presents and summarizes the current literature about the use of lithium in treatment of affective disorders, as well as its effects on cellular physiology, with a separate description of the effect of this ion on the functioning of nerve tissue and ion-molecular mechanisms.

Keywords:

lithium
mood stabilizers
bipolar disorder
glycogen synthase kinase 3β
neuroprotection
neurogenesis

Authors:

Losenkov I.S.

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences

Plotnikov E.V.

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences

Epimakhova E.V.

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences

Bokhan N.A.

Mental Health Research Institute of the Tomsk National Research Medical Center of the Russian Academy of Science

Received:

04.02.2020

Accepted:

06.02.2020

Close metadata

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