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Kaleda V.G.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva

Bozjko O.V.

Mental Health Research Center, Moscow, Russia

Akhadov T.A.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva

Tomyshev A.S.

Mental Health Research Center, Moscow, Russia

Tikhonov D.V.

Mental Health Research Center, Moscow, Russia

Lebedeva I.S.

Meditsinskiĭ kholding "SM-Klinika"

Savvateeva N.Yu.

Mental Health Research Center, Moscow, Russia

Neuroanatomical brain profile of juvenile shiftlike schizophrenia: morphometry of grey matter in the prefrontal cortex and subcortical structures

Authors:

Kaleda V.G., Bozjko O.V., Akhadov T.A., Tomyshev A.S., Tikhonov D.V., Lebedeva I.S., Savvateeva N.Yu.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2019;119(8): 7‑11

DOI: 10.17116/jnevro20191190817

Read: 1817 times

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Table of contents

NEUROANATOMICAL BRAIN PROFILE OF JUVENILE SHIFTLIKE SCHIZOPHRENIA: MORPHOMETRY OF GREY MATTER IN THE PREFRONTAL CORTEX AND SUBCORTICAL STRUCTURES
NEUROANATOMICAL BRAIN PROFILE OF JUVENILE SHIFTLIKE SCHIZOPHRENIA: MORPHOMETRY OF GREY MATTER IN THE PREFRONTAL CORTEX AND SUBCORTICAL STRUCTURES

To cite this article:

Kaleda VG, Bozjko OV, Akhadov TA, Tomyshev AS, Tikhonov DV, Lebedeva IS, Savvateeva NYu. Neuroanatomical brain profile of juvenile shiftlike schizophrenia: morphometry of grey matter in the prefrontal cortex and subcortical structures. S.S. Korsakov Journal of Neurology and Psychiatry. 2019;119(8):7‑11. (In Russ.)
https://doi.org/10.17116/jnevro20191190817

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
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Abstract:

Objective. To determine neuroanatomical peculiarities of grey matter in some regions of the prefrontal cortex and several subcortical structures in patients with juvenile shift like schizophrenia (F20 ICD-10). Material and methods. Forty-three young male patients and 54 mentally healthy men without family history of mental diseases underwent structural MRI with T1 high resolution images. Results. As compared to mentally healthy subjects, there was a decrease of grey matter thickness in all tested regions of the prefrontal cortex in patients. No between-group differences in subcortical structures volumes were found. No correlations between structural changes and psychopathological symptoms were observed. Conclusion. Structural abnormalities of the frontal lobes in juvenile shift like schizophrenia are not associated with severity of psychopathological symptoms.

Keywords:

juvenile shift like schizophrenia
MRI
prefrontal cortex
subcortical structures
PANSS

Authors:

Kaleda V.G.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva

Bozjko O.V.

Mental Health Research Center, Moscow, Russia

Akhadov T.A.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva

Tomyshev A.S.

Mental Health Research Center, Moscow, Russia

Tikhonov D.V.

Mental Health Research Center, Moscow, Russia

Lebedeva I.S.

Meditsinskiĭ kholding "SM-Klinika"

Savvateeva N.Yu.

Mental Health Research Center, Moscow, Russia

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