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Murakhovskaya Yu.K.

Krasnov Research Institute of Eye Diseases;
I.M. Sechenov First Moscow State Medical University (Sechenov University)

Sheremet N.L.

Krasnov Research Institute of Eye Diseases

Eliseeva D.D.

Research Center of Neurology

Bryukhov V.V.

Research Center of Neurology

Brain magnetic resonance imaging features in Leber’s hereditary optic neuropathy

Authors:

Murakhovskaya Yu.K., Sheremet N.L., Eliseeva D.D., Bryukhov V.V.

More about the authors

Journal: Russian Annals of Ophthalmology. 2024;140(5): 146‑153

DOI: 10.17116/oftalma2024140051146

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BRAIN MAGNETIC RESONANCE IMAGING FEATURES IN LEBER’S HEREDITARY OPTIC NEUROPATHY
BRAIN MAGNETIC RESONANCE IMAGING FEATURES IN LEBER’S HEREDITARY OPTIC NEUROPATHY

To cite this article:

Murakhovskaya YuK, Sheremet NL, Eliseeva DD, Bryukhov VV. Brain magnetic resonance imaging features in Leber’s hereditary optic neuropathy. Russian Annals of Ophthalmology. 2024;140(5):146‑153. (In Russ.)
https://doi.org/10.17116/oftalma2024140051146

Подписка 2025-2 (Russian Annals of Ophthalmology)
 
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Leber’s hereditary optic neuropathy (LHON) is the most common inherited mitochondrial disease, characterized by the development of bilateral partial optic nerve atrophy. Modern neuroimaging technologies enable the acquisition of high-quality images, allowing for the evaluation of all structural components of the orbits, including the optic nerve. Consequently, the relevance of performing magnetic resonance imaging (MRI) in patients with LHON has increased. MRI is an essential tool for clarifying the topographic localization and the extent of the pathological process in LHON, both within and beyond the visual system. Correlating MRI findings with the clinical manifestations of LHON can help in predicting disease progression and assessing the effectiveness of therapy.

Keywords:

optic neuropathy
Leber`s hereditary optic neuropathy
magnetic resonance imaging

Authors:

Murakhovskaya Yu.K.

Krasnov Research Institute of Eye Diseases;
I.M. Sechenov First Moscow State Medical University (Sechenov University)

Sheremet N.L.

Krasnov Research Institute of Eye Diseases

Eliseeva D.D.

Research Center of Neurology

Bryukhov V.V.

Research Center of Neurology

Received:

14.03.2024

Accepted:

13.06.2024

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