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Murakhovskaya Yu.K.
Krasnov Research Institute of Eye Diseases;
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Brain magnetic resonance imaging features in Leber’s hereditary optic neuropathy
Journal: Russian Annals of Ophthalmology. 2024;140(5): 146‑153
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To cite this article:
Murakhovskaya YuK, Sheremet NL, Eliseeva DD, Bryukhov VV. Brain magnetic resonance imaging features in Leber’s hereditary optic neuropathy. Russian Annals of Ophthalmology.
2024;140(5):146‑153. (In Russ.)
https://doi.org/10.17116/oftalma2024140051146
Leber’s hereditary optic neuropathy (LHON) is the most common inherited mitochondrial disease, characterized by the development of bilateral partial optic nerve atrophy. Modern neuroimaging technologies enable the acquisition of high-quality images, allowing for the evaluation of all structural components of the orbits, including the optic nerve. Consequently, the relevance of performing magnetic resonance imaging (MRI) in patients with LHON has increased. MRI is an essential tool for clarifying the topographic localization and the extent of the pathological process in LHON, both within and beyond the visual system. Correlating MRI findings with the clinical manifestations of LHON can help in predicting disease progression and assessing the effectiveness of therapy.
Authors:
Murakhovskaya Yu.K.
Krasnov Research Institute of Eye Diseases;
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Received:
14.03.2024
Accepted:
13.06.2024
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