Objective. To study the efficacy of vinpocetine (cavinton comfort) in the treatment of vestibular disorders in patients with chronic cerebral ischemia. Material and methods. A prospective study included 82 patients (43 men and 39 women, aged 61—75 years, mean age 63,8±5,4 years, with chronic cerebrovascular disease (1—2 stages) with vestibular disorders. Patients were divided into two groups. Patients of the main group were treated with cavinton comfort (10 mg three times per day during 60 days), while patients of the control group did not receive the drug. Subjective and objective symptoms of chronic cerebral ischemia were assessed on a 5-point scale. The results of objective otoneurological examination and auditory evoked potentials were also taken into account in assessing the effectiveness of therapy. Results. The main clinical symptoms comprised vestibular disorders, cephalgia and asthenic syndrome. The reduction in subjective symptoms was noted in 71% of patients in the main group and 34% in the control group and improvement of objective manifestations in 74% and 37%, respectively. The efficacy of cavinton comfort was confirmed by the results of auditory evoked potentials. There was a decrease in the latency of the main peaks and increase in their amplitude (bilaterally). Conclusion. Cavinton comfort is an effective treatment of vestibular disorders, associated with central lesions of the vestibular system.