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Esin O.R.

Kazan (Volga region) Federal University;
Clinic of Otorhinolaryngology

Khayrullin I.Kh.

Kazan (Volga region) Federal University

Esin R.G.

Kazan State Medical Academy — Branch of the Russian Medical Academy of Continuing Professional Education;
Kazan (Volga Region) Federal University

Tokareva N.V.

Kazan Federal University

Tension type headache: GABA-ergic drug anvifen efficacy

Authors:

Esin O.R., Khayrullin I.Kh., Esin R.G., Tokareva N.V.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2016;116(2): 58‑61

DOI: 10.17116/jnevro20161162158-61

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To cite this article:

Esin OR, Khayrullin IKh, Esin RG, Tokareva NV. Tension type headache: GABA-ergic drug anvifen efficacy. S.S. Korsakov Journal of Neurology and Psychiatry. 2016;116(2):58‑61. (In Russ.)
https://doi.org/10.17116/jnevro20161162158-61

Подписка 2025 (S.S. Korsakov Journal of Neurology and Psychiatry)
 
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OBJECTIVE

To assess the efficacy of aminophenylbutyric acid (anvifen), a synthetic GABA-receptor agonist, in the treatment of adult patients with tension type headache (TTH).

MATERIAL AND METHODS

Eighty-seven patients with episodic TTH (ETTH) and 30 patients with chronic TTH (CTTH) were examined. The area under the headache curve, sleep quality, the Hospital Anxiety and Depression Scale (HADS) scores and stress resistance measured by an original questionnaire were evaluated.

RESULTS

Anvifen in dose of 250 mg TID during 3 weeks had a positive effect on all parameters studied, excluding the area under the headache curve in CTTH. Similar results were demonstrated after the subsequent course of treatment for 3 weeks.

CONCLUSION

Anvifen was highly effective in ETTH but less effective in CTTH. A combination of anvifen with antidepressants can be recommended for patients with CTTH.

Keywords:

headache
headache
tension type headache
tension type headache
treatment
treatment
aminophenylbutyric acid
aminophenylbutyric acid
anvifen
anvifen
headache
headache
tension type headache
tension type headache
treatment
treatment
aminophenylbutyric acid
aminophenylbutyric acid
anvifen
anvifen

Authors:

Esin O.R.

Kazan (Volga region) Federal University;
Clinic of Otorhinolaryngology

Khayrullin I.Kh.

Kazan (Volga region) Federal University

Esin R.G.

Kazan State Medical Academy — Branch of the Russian Medical Academy of Continuing Professional Education;
Kazan (Volga Region) Federal University

Tokareva N.V.

Kazan Federal University

List of references:

  1. Ayzenberg I, Katsarava Z, Sborowski A et al. The prevalence of primary headache disorders in Russia: A countrywide survey. Cephalalgia. 2012;32(5):373-381.  https://doi.org/10.1177/0333102412438977
  2. Göbel H, Petersen-Braun M, Soyka D. The epidemiology of headache in Germany: a nationwide survey of a representative sample on the basis of the headache classification of the International Headache Society. Cephalalgia. 1994;14(2):97-106.  https://doi.org/10.1046/j.1468-2982.1994.1402097.x
  3. Zivadinov R, Willheim K, Sepic-Grahovac D et al. Migraine and tension-type headache in Croatia: a population-based survey of precipitating factors. Cephalalgia. 2003;23(5):336-343.  https://doi.org/10.1046/j.1468-2982.2003.00544.x
  4. Katsarava Z, Dzagnidze A, Kukava M et al. Primary headache disorders in the Republic of Georgia: Prevalence and risk factors. Neurology. 2009;73(21):1796-1803. https://doi.org/10.1212/wnl.0b013e3181c34abb
  5. Schwartz B. Epidemiology of Tension-Type Headache. JAMA. 1998;279(5):381.  https://doi.org/10.1001/jama.279.5.381
  6. Lyngberg A. Incidence of Primary Headache: A Danish Epidemiologic Follow-up Study. American Journal of Epidemiology. 2005;161(11):1066-1073. https://doi.org/10.1093/aje/kwi139
  7. Bigal M, Bigal J, Betti M, Bordini C, Speciali J. Evaluation of the Impact of Migraine and Episodic Tension-type Headache on the Quality of Life and Performance of a University Student Population. Headache. 2001;41(7):710-719.  https://doi.org/10.1046/j.1526-4610.2001.041007710.x
  8. Zwart J, Dyb G, Hagen K et al. Depression and anxiety disorders associated with headache frequency. The Nord-Trøndelag Health Study. European Journal of Neurology. 2003;10(2):147-152.  https://doi.org/10.1046/j.1468-1331.2003.00551.x
  9. The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia. 2013;33(9):629-808.  https://doi.org/10.1177/0333102413485658
  10. Есин Р.Г., Есин О.Р., Шамсутдинова Р.Ф. Современные подходы к коррекции дезадаптационных (психовегетативных) расстройств у детей и подростков с головной болью напряжения. Педиатрия. Журнал им. Г.Н. Сперанского. 2015;1:105-111. 
  11. Амелин А.В., Богданова Ю.Н., Корешкина М.И. и др. Диагностика первичных и симптоматических форм хронической ежедневной боли. Журнал неврологии и психиатрии имени С.С. Корсакова. 2011;4:82-84. 
  12. Azimova YuE, Osipova VV. Headache in general practice. Treating Physician. 2014;5:7-9. 
  13. Esin RG, Esin OR, Naprienko MV. Clinical features of headache of tension type and principles of treatment. Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova. 2010;110(9):27-32. 
  14. Matthews J, Altman D, Campbell M, Royston P. Analysis of serial measurements in medical research. BMJ. 1990;300(6719):230-235.  https://doi.org/10.1136/bmj.300.6719.230
  15. Zigmond A, Snaith R. The Hospital Anxiety and Depression Scale. Acta Psychiatrica Scandinavica. 1983;67(6):361-370.  https://doi.org/10.1111/j.1600-0447.1983.tb09716.x
  16. Levin Ya.I., Kovrov G.V., Poluektov M.G. et al. Insomnia: modern diagnostic and therapeutic approaches. Moscow: Eidos Media; 2005.

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