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Suslina Z.A.

Nauchnyĭ tsentr nevrologii RAMN;
kafedra nevrologii fakul'teta usovershenstvovaniia vracheĭ Rossiĭskogo gosudarstvennogo meditsinskogo universiteta;
kafedra patologii cheloveka Pervogo moskovskogo gosudarstvennogo meditsinskogo universiteta im. I.M. Sechenova;
Sankt-Peterburgskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. akad. I.P. Pavlova;
Sankt-Peterburgskaia meditsinskaia akademiia im. I.I. Mechnikova;
Saratovskiĭ gosudarstvennyĭ meditsinskiĭ universitet

Rumiantseva S.A.

Kafedra nevrologii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta

Tanashyan M.M.

Neurology Research Center, Moscow, Russia

Skoromets A.A.

Sankt-Peterburgskiĭ gosudarstvennyĭ meditsinskiĭ institut im. akad. I.P. Pavlova

Klocheva E.G.

Sankt-Peterburgskaia gosudarstvennaia meditsinskaia akademiia im. I.I. Mechnikova

Fedin A.I.

Kafedra nevrologii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta

Kovalenko A.L.

Direktsiia po nauke OOO "NTFF "Polisan", Sankt-Peterburg

Silina E.V.

Kafedra patofiziologii FPPO vracheĭ Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova

Sholomov I.I.

GUZ "Oblastnaia detskaia klinicheskaia bol'nitsa #2", Voronezh

The complex energy correction of chronic brain ischemia

Authors:

Suslina Z.A., Rumiantseva S.A., Tanashyan M.M., Skoromets A.A., Klocheva E.G., Fedin A.I., Kovalenko A.L., Silina E.V., Sholomov I.I.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2011;111(3): 25‑30

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Table of contents

THE COMPLEX ENERGY CORRECTION OF CHRONIC BRAIN ISCHEMIA
THE COMPLEX ENERGY CORRECTION OF CHRONIC BRAIN ISCHEMIA

To cite this article:

Suslina ZA, Rumiantseva SA, Tanashyan MM, et al. . The complex energy correction of chronic brain ischemia. S.S. Korsakov Journal of Neurology and Psychiatry. 2011;111(3):25‑30. (In Russ.)

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Considerable disturbance of all quality of life domains that worsens social adaptation and daily living and results in an asthenic-neurotic syndrome, along with neurologic and mnestic-intellectual disturbances, was revealed in patients with chronic brain ischemia (stages I, II, III). Based on the results of the double blind placebo-controlled trial, the high clinical efficacy of cytoflavin in patients with chronic brain ischemia has been shown. The treatment with cytoflavin decreases the severity of subjective symptoms and complaints thus increasing the working ability of patients, improves balance and gait, decreases the severity of asthenic and neurotic syndromes, improves cognitive and memory functions (information storage, reasoning and attention), positively effects on quality of sleep and all aspects of quality of life, in particular, on physical activity, self-rating of health and viability as well as social activity, mental health and emotional lability.

Keywords:

chronic cerebral ischemia
quality of life
cytoflavin

Authors:

Suslina Z.A.

Nauchnyĭ tsentr nevrologii RAMN;
kafedra nevrologii fakul'teta usovershenstvovaniia vracheĭ Rossiĭskogo gosudarstvennogo meditsinskogo universiteta;
kafedra patologii cheloveka Pervogo moskovskogo gosudarstvennogo meditsinskogo universiteta im. I.M. Sechenova;
Sankt-Peterburgskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. akad. I.P. Pavlova;
Sankt-Peterburgskaia meditsinskaia akademiia im. I.I. Mechnikova;
Saratovskiĭ gosudarstvennyĭ meditsinskiĭ universitet

Rumiantseva S.A.

Kafedra nevrologii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta

Tanashyan M.M.

Neurology Research Center, Moscow, Russia

Skoromets A.A.

Sankt-Peterburgskiĭ gosudarstvennyĭ meditsinskiĭ institut im. akad. I.P. Pavlova

Klocheva E.G.

Sankt-Peterburgskaia gosudarstvennaia meditsinskaia akademiia im. I.I. Mechnikova

Fedin A.I.

Kafedra nevrologii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta

Kovalenko A.L.

Direktsiia po nauke OOO "NTFF "Polisan", Sankt-Peterburg

Silina E.V.

Kafedra patofiziologii FPPO vracheĭ Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova

Sholomov I.I.

GUZ "Oblastnaia detskaia klinicheskaia bol'nitsa #2", Voronezh

List of references:

  1. Gusev E.I., Skvortsova V.I. Ishemiya golovnogo mozga. M: Meditsina 2001.
  2. Kovalenko A.L. Farmakologicheskaya aktivnost' original'nykh lekarstvennykh preparatov na osnove 1-dezoksi-1 (N-metilamino)-D-glyutsitola: Avtoref. dis. … d-ra med. nauk. St-Peterburg 2005.
  3. Kovalenko A.L., Romantsov M.G., Petrov A.Yu. Farmakologicheskaya aktivnost' yantarnoi kisloty i perspektiva ee primeneniya v klinike. Sb statei pod red. M.G. Romantsova 6-20.
  4. Rumyantseva S.A., Silina E.V. Energokorrektsiya i kachestvo zhizni pri khronicheskoi ishemii mozga. M: Meditsinskaya kniga 2007; 60.
  5. Rumyantseva S.A., Silina E.V., Koryukova I.V. Kompleksnaya neiromediatornaya terapiya ostrykh i khronicheskikh ishemicheskikh porazhenii mozga. Zhurn Atmosfera. Nervnye bolezni 2008; 2: 1-6.
  6. Rumyantseva S.A., Fedin A.I., Silina E.V., Bolevich S.B. Antioksidantnaya neiroprotektsiya pri insul'te. St-Peterburg: Taktik-Studio 2008; 104.
  7. Solov'eva E.Yu., Mironova O.P., Baranova O.A. i dr. Svobodnoradikal'nye protsessy i antioksidantnaya terapiya pri khronicheskoi ishemii mozga. M: Zhurn nevrol i psikh 2008; 6: 98-104.
  8. Solov'eva E.Yu. Khronicheskaya ishemiya i okislitel'nyi stress. Kliniko-patogeneticheskie i prognosticheskie aspekty: Avtoref. dis. … d-ra med. nauk. M: 2009; 47.
  9. Suslina Z.A., Fedin A.I., Rumyantseva S.A. i dr. Klinicheskaya effektivnost' tsitoflavina pri distsirkulyatornoi entsefalopatii - khronicheskoi ishemii mozga (rezul'taty mnogotsentrovogo randomizirovannogo issledovaniya). Vestn SPb GMA im. I.I. Mechnikova 2005; 3: 6: 7-14.
  10. Fedin A.I., Rumyantseva S.A. Intensivnaya terapiya ishemicheskogo insul'ta. M: Meditsinskaya kniga 2004; 284.
  11. Fedin A.I., Rumyantseva S.A., Piradov M.A. i dr. Effektivnost' neirometabolicheskogo protektora tsitoflavina pri infarktakh mozga (mnogotsentrovoe randomizirovannoe issledovanie). Vestn Spb GMA im. I.I. Mechnikova 2005; 1: 13-19.
  12. Shkaly, testy i oprosniki v meditsinskoi reabilitatsii. Pod red. A.N. Belovoi, O.N. Shepetovoi. M: Avtodor 2002; 205-224.
  13. Kontos H. Oxygen Radicals in Cerebral Ischemia. Willis Lecture Stroke 2001; 32: 2712-2716.
  14. Niizuma K., Endo H., Chan P. Oxidative stress and mitochondrial dysfunction as determinants of ischemic neuronal death and survival. J Neurochem 2009; 109: 133-138.

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