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Chakhava V.O.

GNTs sotsial'noĭ i sudebnoĭ psikhiatrii im. V.P. Serbskogo, Moskva

Budtueva F.S.

GNTs sotsial'noĭ i sudebnoĭ psikhiatrii im. V.P. Serbskogo, Moskva

Borukaev R.R.

GNTs sotsial'noĭ i sudebnoĭ psikhiatrii im. V.P. Serbskogo, Moskva

Efficacy of adepress (paroxetin) in generalized anxiety disorder

Authors:

Chakhava V.O., Budtueva F.S., Borukaev R.R.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2010;110(8): 25‑29

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Table of contents

EFFICACY OF ADEPRESS (PAROXETIN) IN GENERALIZED ANXIETY DISORDER
EFFICACY OF ADEPRESS (PAROXETIN) IN GENERALIZED ANXIETY DISORDER

To cite this article:

Chakhava VO, Budtueva FS, Borukaev RR. Efficacy of adepress (paroxetin) in generalized anxiety disorder. S.S. Korsakov Journal of Neurology and Psychiatry. 2010;110(8):25‑29. (In Russ.)

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The aim of the study was to evaluate efficacy of adepress (paroxetin) in different clinical variants of generalized anxiety disorder (GAD). Adepress was used as a monotherapy during 42 days. Patient's state was assessed using Hamilton anxiety scale (HAM-A) at baseline and every week thereafter. The study included 49 patients aged 36,2±8,2 years. Patients were stratified into two groups according to the predominance of somatic (24 cases) or cognitive (21 cases) anxiety. The efficacy of adepress was shown both in a separate GAD and in a GAD with comorbid psychopathology. The effect of the drug was seen in patients with somatic anxiety after 3-4 weeks and in patients with cognitive anxiety after 3-6 weeks.

Keywords:

generalized anxiety disorder
somatic anxiety
cognitive anxiety
treatment
adepress (paroxetin)

Authors:

Chakhava V.O.

GNTs sotsial'noĭ i sudebnoĭ psikhiatrii im. V.P. Serbskogo, Moskva

Budtueva F.S.

GNTs sotsial'noĭ i sudebnoĭ psikhiatrii im. V.P. Serbskogo, Moskva

Borukaev R.R.

GNTs sotsial'noĭ i sudebnoĭ psikhiatrii im. V.P. Serbskogo, Moskva

List of references:

  1. Avedisova A.S. Venlafaksin (velaksin): rezul'taty mezhdunarodnykh issledovanii antidepressanta III pokoleniya. Consilium Medicum 2006;11:14:3.
  2. Aleksandrovskii Yu.A. Pogranichnye psikhicheskie rasstroistva. 2-e izd. Rostov-na-Donu: Feniks 1997;579.
  3. Akhapkin R.V. Primenenie preparata plizil (paroksetin) v psikhiatricheskoi praktike. Psikhiat i psikhofarmakoter ;10:3:61-66.
  4. Less Yu.E. Generalizovannoe trevozhnoe rasstroistvo: tipologiya i komorbidnye sostoyaniya. Ros psikhiat zhurn 2008;2:40-45.
  5. Mosolov S.N. Klinicheskoe primenenie sovremennykh antidepressantov. St-Peterburg 1995.
  6. Mosolov S.N. Osnovy psikhofarmakoterapii. M 1996.
  7. Morozov P.V. Terapiya depressii i trevozhnykh rasstroistv v sovremennoi psikhiatrii. Psikhiat i psikhofarmakoter 2005;7:3.
  8. Smulevich A.B. Antidepressanty v obshchemeditsinskoi praktike. Consilium Medicum 2002;3-7 (prilozhenie).
  9. Chakhava V.O., Less Yu.E., Malygin Ya.V. Effektivnost' preparata Reksetin u bol'nykh s generalizovannym trevozhnym rasstroistvom. Ros med zhurn 2007;15:24:305:1860-1866.
  10. Chakhava V.O., Less E.Yu., Borukaev R.R. Effektivnost' primeneniya venlafaksina pri trevozhnoi depressii i generalizovannom trevozhnom rasstroistve. Ros psikhiat zhurn 2007;2:85-89.
  11. Brawman-Mintzer O. Pharmacologic treatment of generalized anxiety disorder. Psychiatr Clin North Am 2001;24:119-137.
  12. Ballenger J.C., Davidson J.R.T., Lecrubier Y. et al.  Consensus statement on generalized anxiety disorder from the International Consensus group on Depression and anxiety. J Clin Physiat 2001;62:Suppl 11:53-58.
  13. Gelenberg A.J., Lydiard R.B., Rudolph R.L. et al. Efficacy of Venlafaxine Extended-Release Capsules in Nondepressed Outpatients With Generalized Anxiety Disorder. JAMA 2000;283:3082-3088.
  14. Hedges D.W., Reimherr F.W., Strong R.E. et al. An open trial of nefazodone in adult patients with generalized anxiety disorder. Psychopharmacol Bull 1996;32:4:671-676.
  15. Hoehn-Saric R., McLeod D.R., Zimmerli W.D. Differential effects of alprazolam and imipramine in generalized anxiety disorder: somatic versus psychic symptoms. J Clin Psychiat 1988;49:293-301.
  16. Klein D.F. Delineation of two drug-responsive anxiety syndromes. Psychopharmacologia 1964;5:397-408.
  17. Raj A., Sheehan D. Antidepressants in the treatment of Generalized Anxiety Disorder. In: Generalized Anxiety Disorder. Eds. D. Nutt, K. Rickels, D. Stein. Martin Dunitz Ltd 2002;137-152.
  18. Rickels K., Downing R., Schweizer E., Hassman H. Antidepressants for the treatment of generalized anxiety disorder. Arch Gen Psychiat 1993;50:884-895.
  19. Rocca P., Fonzo P., Scotta M. et al.  Paroxetine efficacy in the treatment of generalized anxiety disorder. Acta Psychiat Scand 1997;95:444-450.

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