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Kryukov A.I.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology;
Pirogov Russian National Research Medical University

Garov E.V.

Sverzhevky Research Clinical Institute of Otorhinolaryngology

Zelenkova V.N.

Research Clinical Institute of Otorinolaryngology named after. L.I. Sverzhevsky

Sudarev P.A.

Sverzhevskiy Research Clinical Institute of Otorhinolaryngology

Kaloshina A.S.

L.I. Sverzhevskiy Research Institute of Clinical Otorhinolaryngology of the Moscow Department of Healthcare, Russian Federation

Garova E.E.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology

Hublaryan A.G.

L.I. Sverzhevskiy Research Institute of Clinical Otorhinolaryngology

Statsenko Ya.A.

L.I. Sverzhevskiy Research Institute of Clinical Otorhinolaryngology

Neuroendocrine adenoma middle ear

Authors:

Kryukov A.I., Garov E.V., Zelenkova V.N., Sudarev P.A., Kaloshina A.S., Garova E.E., Hublaryan A.G., Statsenko Ya.A.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2022;87(5): 63‑69

DOI: 10.17116/otorino20228705163

Views: 2259

Downloaded: 73

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Table of contents

NEUROENDOCRINE ADENOMA MIDDLE EAR
NEUROENDOCRINE ADENOMA MIDDLE EAR

To cite this article:

Kryukov AI, Garov EV, Zelenkova VN, et al. . Neuroendocrine adenoma middle ear. Russian Bulletin of Otorhinolaryngology. 2022;87(5):63‑69. (In Russ.)
https://doi.org/10.17116/otorino20228705163

Подписка 2025-2 (Russian Bulletin of Otorhinolaryngology)
 
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Neuroendocrine adenoma (NEA) is an extremely rare pathology and accounts for less than 2% of all ear tumors. The article provides an overview of the diagnosis, classification, treatment methods and algorithm for monitoring patients with NEA of the middle ear. 6 cases of NEA of the tympanic cavity are described in detail, which were diagnosed and treated in GBUZ NIKIO named after N.N. L.I. Sverzhevsky DZM for the last 5 years. Diagnosis of NEA of the middle ear is possible when performing high-resolution multislice computed tomography of the temporal bones and magnetic resonance imaging with contrast enhancement, however, the neoplasm can be verified only after a histological examination with the determination of the immunophenotype. Differential diagnosis of NEA of the tympanic cavity with other processes of the middle ear must be carried out at each stage of the diagnostic path. Surgical treatment, depending on the volume of education, allows you to remove it completely and improve the auditory function.

Keywords:

neuroendocrine adenomas of the middle ear
diagnosis
classification
surgical treatment

Authors:

Kryukov A.I.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology;
Pirogov Russian National Research Medical University

Garov E.V.

Sverzhevky Research Clinical Institute of Otorhinolaryngology

Zelenkova V.N.

Research Clinical Institute of Otorinolaryngology named after. L.I. Sverzhevsky

Sudarev P.A.

Sverzhevskiy Research Clinical Institute of Otorhinolaryngology

Kaloshina A.S.

L.I. Sverzhevskiy Research Institute of Clinical Otorhinolaryngology of the Moscow Department of Healthcare, Russian Federation

Garova E.E.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology

Hublaryan A.G.

L.I. Sverzhevskiy Research Institute of Clinical Otorhinolaryngology

Statsenko Ya.A.

L.I. Sverzhevskiy Research Institute of Clinical Otorhinolaryngology

Received:

28.07.2021

Accepted:

14.09.2021

List of references:

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  2. Murphy G, Pilch B, Dickersin G, Goodman M, Nadol J, Jr. Carcinoid tumor of the middle ear. American Journal of Clinical Pathology. 1980;73(6):816-823.  https://doi.org/10.1093/ajcp/73.6.816
  3. Marinelli J, Cass S, Mann S, Haynes D, Hunter J, Isaacson B, Sweeney A, Pelosi S, Willcox T, O’Connell B, Rivera M, Lane J, Carlson M. Adenomatous neuroendocrine tumors of the middle ear: a multi-institutional investigation of 32 cases and development of a staging system. Otology and Neurotology. 2018;39(8):712-721.  https://doi.org/10.1097/MAO.0000000000001905
  4. Bell D, El-Naggar A, Gidley P. Middle ear adenomatous neuroendocrine tumors: a 25-year experience at MD Anderson Cancer Center. Virchows Archiv. 2017;471(5): 667-672.  https://doi.org/10.1007/s00428-017-2155-6
  5. Cardoso F, Monteiro E, Lopes L, Avila M, Scarioli B. Adenomatous tumors of the middle ear: a literature review. Archives of Otorhinolaryngology. 2017;21(3):308-312.  https://doi.org/10.1055/s-0037-1601400
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