The relationship between intraocular pressure and age-related variations in ocular rigidity

Svetlova O.V.

Academician I.P. Pavlov First St. Petersburg State Medical University;
North-Western State Medical University named after I.I. Mechnikov

ORCID: 0000-0001-7777-1901

Koshits I.N.

OOO Piterkom-Seti / MS Konsultatcionnaia gruppa

ORCID: 0000-0002-7920-9469

Pankratov R.M.

OOO Oftalmologicheskaia lazernaia klinika

ORCID: 0009-0001-4393-065X

Makarovskaya O.V.

OOO Oftalmologicheskaia lazernaia klinika

ORCID: 0009-0000-9193-7349

Zaseeva M.V.

Academician I.P. Pavlov First St. Petersburg State Medical University

ORCID: 0009-0005-3279-0099

The relationship between intraocular pressure and age-related variations in ocular rigidity

Authors:

Svetlova O.V., Koshits I.N., Pankratov R.M., Makarovskaya O.V., Zaseeva M.V.

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Journal: Russian Annals of Ophthalmology. 2024;140(3): 11‑18

DOI: 10.17116/oftalma202414003111

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To cite this article:

Svetlova OV, Koshits IN, Pankratov RM, Makarovskaya OV, Zaseeva MV. The relationship between intraocular pressure and age-related variations in ocular rigidity. Russian Annals of Ophthalmology. 2024;140(3):11‑18. (In Russ.)
https://doi.org/10.17116/oftalma202414003111

Подписка 2025 (Russian Annals of Ophthalmology)

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PURPOSE

This study aimed to identify the correlation between age-related fluctuations in the average values of rigidity of the fibrous tunic of the eye (FTE) and corresponding ranges of true intraocular pressure (IOP) in healthy eyes and eyes with open-angle glaucoma (OAG); using the identified ranges of FTE rigidity, to establish the appropriate IOP zones for healthy and glaucomatous eyes, taking into account the aging periods as classified by the World Health Organization (WHO).

MATERIAL AND METHODS

Ocular-Response Analyzer tonometry was used according to the Koshits-Svetlova dynamic diagnostic method to examine 674 patients with healthy eyes and 518 patients with glaucomatous eyes, aged 18 to 90 years, classified according to the WHO aging periods, and a theoretical analysis was conducted to estimate clinical values of FTE rigidity, the current level of true IOP, and the calculated individual IOP level in a patient’s eye during youth.

RESULTS

The following IOP level zones were identified for patients with healthy and glaucomatous eyes: low IOP zone (≤13 mm Hg); medium IOP zone (14—20 mm Hg); elevated IOP zone (21—26 mm Hg); high IOP zone (27—32 mm Hg); subcompensated IOP zone (33—39 mm Hg); and decompensated IOP zone (≥40 mm Hg).

CONCLUSION

The fundamental physiological criterion “rigidity” does not depend on central corneal thickness and consistently reflects the current level of true IOP. In all examined patients, both with healthy and glaucomatous eyes, healthy and glaucoma eyes with the same level of current rigidity had the same level of IOP. The ability to assign a given healthy or glaucomatous eye to a specific individual IOP zone is particularly important for the polyclinic system.

Keywords:

intraocular pressure

pneumotonometry

individual zones of intraocular pressure

glaucoma

age-related ophthalmic hypertension

fibrous tunic of the eye

rigidity

fluctuation

biomechanics of the eye

sclera

Authors:

Svetlova O.V.

Academician I.P. Pavlov First St. Petersburg State Medical University;
North-Western State Medical University named after I.I. Mechnikov

ORCID: 0000-0001-7777-1901

Koshits I.N.

OOO Piterkom-Seti / MS Konsultatcionnaia gruppa

ORCID: 0000-0002-7920-9469

Pankratov R.M.

OOO Oftalmologicheskaia lazernaia klinika

ORCID: 0009-0001-4393-065X

Makarovskaya O.V.

OOO Oftalmologicheskaia lazernaia klinika

ORCID: 0009-0000-9193-7349

Zaseeva M.V.

Academician I.P. Pavlov First St. Petersburg State Medical University

ORCID: 0009-0005-3279-0099

Received:

10.04.2023

Accepted:

11.05.2023

List of references:

Nesterov AP. Basic principles of diagnosis of POAG. Russian Annals of Ophthalmology = Vestnik oftalmologii. 1998;2(114):3-6. (In Russ.).
Leydhecker W. The intraocular pressure: Clinical aspects. Ann Ophthalmol. 1976;8(4):398-399.
Zaseeva MV. Study of the rigidity of the sclera in healthy and glaucoma eyes: Dis. ... kand. med. nauk. SPb.: Military Medical Academy; 2009. (In Russ.). Accessed 21.03.23. https://medical-diss.com/medicina/issledovanie-rigidnosti-sklery-v-zdorovyh-i-glaukomnyh-glazah
Svetlova OV. Functional features of interaction of sclera, accommodation and drainage systems of the eye in glaucoma and myopic pathology: Dis. ... d-ra. med. nauk. M.: Peoples’ Friendship University of Russia; 2010. (In Russ.). Accessed 21.03.23. https://medical-diss.com/medicina/funktsionalnye-osobennosti-vzaimodeystviya-sklery-akkomodatsionnoy-i-drenazhnoy-sistem-glaza-pri-glaukomnoy-i-miopichesko
Svetlova OV, Koshits IN, Drozdova GA, Zaseeva MV, Lenkevich AV. A practical method for determining individual pressure in youth and the level of reduction of sclera rigidity in old age for calculating the parameters of hypotensive operations of a new type (Part I). Glaucoma. 2008;(4):49-64 (In Russ.).
Svetlova OV, Koshits IN, Drozdova GA, Zaseeva MV, Lenkevich AV. A practical method for determining individual pressure in youth and the level of reduction of sclera rigidity in old age for calculating the parameters of hypotensive operations of a new type (Part II). Glaucoma. 2009;(1)::46-53 (In Russ.).
Svetlova OV, Koshits IN. Fiziologicheskiye funktsii fibroznoy obolochki glaza i ikh ispolnitel’nyye mekhanizmy. Normal’naya i patologicheskaya fiziologiya glaza: Uchebnoye posobiye [Physiological functions of the fibrous membrane of the eye and their executive mechanisms. Normal and pathological physiology of the eye: A textbook]. SPb.: I.I. Mechnikov NWSMU; 2014. (In Russ.).
Koshits IN, Svetlova OV. On the physiological essence of intraocular pressure. Part 2. The role of sclera fluctuation in ensuring the constancy of the daily volume of watery moisture flowing through the eye. National Journal of Glaucoma = Natsional’nyi zhurnal glaucoma. 2019;18(2):76-92. (In Russ.). https://doi.org/10.25700/NJG.2019.02.09
Vit VV. Stroyeniye zritel’noy sistemy cheloveka [The structure of the human visual system]. Odessa: Astroprint; 2003. (In Russ.).
Svetlova OV, Drozdova GA, Balashevich LI, Zaseeva MV, Ryabtseva AA, Makarov FN, Koshits IN. Morphophysiological features of the structure of the human eye sclera as a key link in the formation of the level of intraocular pressure in normal and glaucoma. Morphology = Morfologia. 2009;5(136): 5-10. (In Russ.).
Svetlova OV, Zaseeva MV, Koshits IN. The rigidity of the sclera is a reliable criterion for assessing the level and range of IOP jumps in healthy and glaucoma eyes. In: S’yezd oftal’mologov. Rossii, 8-y: Sb. nauch. tr. [Russia Congress of ophthalmologists, 8th: Collection of scientific papers]. M. 2005;214-215 (In Russ.).
Svetlova O, Koshits I, Guseva M, Makarov F. Two key managers in the pathogenesis of OAG and innovative methods of early diagnosis. 7th World Glaucoma Congress. Helsinki; 2017.

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