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Filippov V.M.

Research Institute of Eye Diseases

Petrachkov D.V.

Research Institute of Eye Diseases

Budzinskaya M.V.

Krasnov Research Institute of Eye Diseases

Sidamonidze A.L.

Research Institute of Eye Diseases

Modern concepts of pathogenesis of diabetic retinopathy

Authors:

Filippov V.M., Petrachkov D.V., Budzinskaya M.V., Sidamonidze A.L.

More about the authors

Journal: Russian Annals of Ophthalmology. 2021;137(5‑2): 306‑313

DOI: 10.17116/oftalma2021137052306

Views: 3688

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To cite this article:

Filippov VM, Petrachkov DV, Budzinskaya MV, Sidamonidze AL. Modern concepts of pathogenesis of diabetic retinopathy. Russian Annals of Ophthalmology. 2021;137(5‑2):306‑313. (In Russ.)
https://doi.org/10.17116/oftalma2021137052306

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This literature review presents modern view on the pathogenesis of diabetic retinopathy (DR) paying particular attention to the molecular mechanisms leading to its development, as well as the manifestations of retinal neurodegeneration in such patients. Assessment of this condition and its clinical manifestations makes it possible to diagnose DR at the stage of absent initial vascular changes. Investigating the neurodegeneration mechanisms could supplement the existing understanding of the disease pathogenesis and could possibly help find new ways of treatment and prevention of DR.

Keywords:

diabetes mellitus
diabetic retinopathy
pathogenesis
neurodegeneration

Authors:

Filippov V.M.

Research Institute of Eye Diseases

Petrachkov D.V.

Research Institute of Eye Diseases

Budzinskaya M.V.

Krasnov Research Institute of Eye Diseases

Sidamonidze A.L.

Research Institute of Eye Diseases

Received:

25.11.2020

Accepted:

27.04.2021

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