Когнитивные нарушения у пациентов с болезнью Паркинсона

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Болезнь Паркинсона (БП) проявляется как моторными, так и немоторными симптомами, среди которых важное место занимают когнитивные нарушения. В статье приводится обзор спектра когнитивных расстройств при БП, разбирается их патоморфологическая и нейротрансмиттерная основа. Обсуждаются факторы риска, критерии диагностики, вопросы комплексной терапии, включающей как нейротрансмиттерные, так и нейротрофические препараты, методы физической и когнитивной реабилитации.

Ключевые слова:

болезнь Паркинсона

когнитивные нарушения

деменция

умеренное когнитивное расстройство

патогенез

терапия

нейротрофическая терапия

Авторы:

Катунина Е.А.

ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России (Пироговский университет);
ФГБУ «Федеральный центр мозга и нейротехнологий» Федерального медико-биологического агентства России

ORCID: 0000-0001-5805-486X

Парусова А.В.

ФГБУ «Федеральный центр мозга и нейротехнологий» Федерального медико-биологического агентства России

ORCID: 0009-0001-1366-766X

Голованова И.В.

ГБУЗ «Городская клиническая больница №1 имени Н.И. Пирогова Департамента здравоохранения Москвы»

ORCID: 0009-0005-8365-6113

Завадцева Н.В.

ГБУЗ «Городская клиническая больница №1 имени Н.И. Пирогова Департамента здравоохранения Москвы»

ORCID: 0009-0007-1823-2300

Дата поступления:

09.10.2024

Дата принятия в печать:

14.10.2024

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