The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Stoyukhina A.S.

Krasnov Research Institute of Eye Diseases

Tumor-like diseases and retinal hamartomas in ophthalmological practice

Authors:

Stoyukhina A.S.

More about the authors

Journal: Russian Annals of Ophthalmology. 2020;136(4): 367‑372

DOI: 10.17116/oftalma2020136042367

Read: 11165 times

Download PDF (RU)
Contact the author
Table of contents

TUMOR-LIKE DISEASES AND RETINAL HAMARTOMAS IN OPHTHALMOLOGICAL PRACTICE
TUMOR-LIKE DISEASES AND RETINAL HAMARTOMAS IN OPHTHALMOLOGICAL PRACTICE

To cite this article:

Stoyukhina AS. Tumor-like diseases and retinal hamartomas in ophthalmological practice. Russian Annals of Ophthalmology. 2020;136(4):367‑372. (In Russ.)
https://doi.org/10.17116/oftalma2020136042367

Подписка 2026 Вестник офтальмологии (Russian Annals of Ophthalmology)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Morphometric analysis of small reti­noblastomas following combination chemotherapy. Russian Annals of Ophthalmology. 2025;(2):38-43
Diagnostic capa­bilities of opti­cal cohe­rence tomo­graphy in obstruction of the upper lacrimal pathway. Russian Annals of Ophthalmology. 2025;(3):37-47
OCT patterns as a source of errors in the diagnosis of intraocular tumors. Russian Annals of Ophthalmology. 2025;(3):63-70
Nano­second reti­nal laser therapy: three years of practical expe­rience. Russian Annals of Ophthalmology. 2025;(4):60-65
Mole­cular diagnostic biomarkers of subretinal fluid in asse­ssing the seve­rity and prognosis of rhegmatogenous reti­nal deta­chment. Russian Annals of Ophthalmology. 2025;(6):119-126
Intravascular physiology and imaging in dete­rmining the indi­cations for reva­scularization in patients with inte­rmediate coro­nary stenosis. Russian Journal of Cardiology and Cardiovascular Surgery. 2025;(3):255-260
Clinical and economic impact of broader implementation of opti­cal cohe­rence tomo­graphy and anti-VEGF therapy for diabetic reti­nopathy and macu­lar edema in type 1 diabetes. Medi­cal Technologies. Asse­ssment and Choice. 2026;(1):122-133
Abstract:

The article provides a detailed review of the ophthalmoscopic picture, optical coherence tomography (OCT) of the retina and fundus autofluorescence in patients with such rare pathological processes in the fundus as torpedo maculopathy, retinal myelin fibers, retinal astrocytic hamartoma and cavernous hematoma.

Keywords:

optical coherence tomography
torpedo maculopathy
retinal myelin fibers
retinal astrocytic hamartoma
cavernous retinal hemangioma

Authors:

Stoyukhina A.S.

Krasnov Research Institute of Eye Diseases

Received:

30.03.2020

Accepted:

23.04.2020

Close metadata

References:

  1. Venkatesh R, Bavaharan B, Yadav N. Multicolor imaging findings in torpedo maculopathy. Indian Journal of Ophthalmology. 2019;67(2):295-297.  https://doi.org/10.4103/ijo.IJO_1317_18
  2. Roseman RL, Gass JDM. Solitary Hypopigmented Nevus of the Retinal Pigment Epithelium in the Macula. Archives of Ophthalmology. 1992;110(10): 1358-1359. https://doi.org/10.1001/archopht.1992.01080220020005
  3. Cherney E. Torpedo Maculopathy. Oftal’mologicheskie vedomosti. 2013;6(3): 80-82. (In Russ.). https://doi.org/10.17816/OV2013380-82
  4. Trevino R, Kiani S, Raveendranathan P. The expanding clinical spectrum of torpedo maculopathy. Optometry and Vision Science. 2014;91(4 suppl 1):71-78.  https://doi.org/10.1097/OPX.0000000000000181
  5. Stoyukhina AS, Zhorzholadze NV, Danilov SS. Torpedo macu-lopathy (clinical case). Vestnik oftal’mologii. 2017;133(5):56-62. (In Russ.). https://doi.org/10.17116/oftalma2017133556-62
  6. Buzzonetti L, Petroni S, Catena G, Iarossi G. Optical coherence tomography and electrophysiological findings in torpedo maculopathy. Documenta Ophthalmologica. 2015;130(1):65-70.  https://doi.org/10.1007/s10633-014-9472-8
  7. Pilotto E, Zannin ME, Convento E, Cortese M, Midena E. Torpedo maculopathy: A morphofunctional evaluation. International Ophthalmology. 2013;33(1):71-74.  https://doi.org/10.1007/s10792-012-9618-1
  8. Wong EN, Fraser-Bell S, Hunyor AP, Chen FK. Novel optical coherence tomography classification of torpedo maculopathy. Clinical and Experimental Ophthalmology. 2015;43(4):342-348.  https://doi.org/10.1111/ceo.12435
  9. Pian D, Ferrucci S, Anderson SF, Wu C. Paramacular coloboma. Optometry and Vision Science. 2003;80(8):556-563.  https://doi.org/10.1097/00006324-200308000-00008
  10. Teitelbaum BA, Hachey DL, Messner LV. Torpedo maculopathy. Journal of the American Optometric Association. 1997;68(6):373-376. 
  11. Tripathy K, Sarma B, Mazumdar S. Commentary: Inner retinal excavation in torpedo maculopathy and proposed type 3 lesions in optical coherence tomography. Indian Journal of Ophthalmology. 2018;66(8):1213-1214. https://doi.org/10.4103/ijo.IJO_656_18
  12. Schuerch K, Ebneter A, Zinkernagel M. Two case reports of torpedo maculopathy. Klinische Monatsblätter für Augenheilkunde. 2015;232(4):558-559.  https://doi.org/10.1055/s-0035-1545805
  13. Jurjevic D, Böni C, Barthelmes D, Fasler K, Becker M, Michels S, Stemmle J, Herbort C, Zweifel SA. Torpedo Maculopathy Associated with Choroidal Neovascularization. Klinische Monatsblätter für Augenheilkunde. 2017; 234(4):508-514.  https://doi.org/10.1055/s-0043-100230
  14. Shirley K, O’Neill M, Gamble R, Ramsey A, McLoone E. Torpedo maculopathy: disease spectrum and associated choroidal neovascularisation in a paediatric population. Eye (London, England). 2018;32(8):1315-1320. https://doi.org/10.1038/s41433-018-0074-7
  15. Parodi MB, Romano F, Montagna M, Albertini GC, Pierro L, Arrigo A, Bandello F. Choroidal neovascularization in torpedo maculopathy assessed on optical coherence tomography angiography. Ophthalmic Surgery, Lasers and Imaging Retina. 2018;49(11):210-213.  https://doi.org/10.3928/23258160-20181101-20
  16. Teich SA. Disappearance of Myelinated Retinal Nerve Fibers After a Branch Retinal Artery Occlusion. American Journal of Ophthalmology. 1987;103(6): 835-837.  https://doi.org/10.1016/S0002-9394(14)74409-5
  17. Duval R, Hammamji K, Aroichane M, Michaud JL, Ospina LH. Acquired myelinated nerve fibers in association with optic disk drusen. Journal of AAPOS. 2010;14(6):544-547.  https://doi.org/10.1016/j.jaapos.2010.08.008
  18. Baarsma GS. Acquired medullated nerve fibres. British Journal of Ophthalmology.1980;64(9):651.  https://doi.org/10.1136/bjo.64.9.651
  19. Bass SJ, Westcott J, Sherman J. OCT in a myelinated retinal nerve fiber syndrome with reduced vision. Optometry and Vision Science. 2016;93(10):1285-1291. https://doi.org/10.1097/OPX.0000000000000951
  20. Nangia V, Jonas JB, Khare A, Bhate K, Agarwal S, Panda-Jonas S. Prevalence of myelinated retinal nerve fibres in adult Indians: the Central India Eye and Medical Study. Acta Ophthalmologica. 2014;92(3):235-236.  https://doi.org/10.1111/aos.12118
  21. Lee MS, Gonzalez C. Unilateral peripapillary myelinated retinal nerve fibers associated with strabismus, amblyopia, and myopia. American Journal of Ophthalmology. 1998;125(4):554-556.  https://doi.org/10.1016/S0002-9394(99)80199-8
  22. Jain DH, Natarajan KK. Rare association of optic disk pits with myelinated retinal nerves. Journal of Pediatric Ophthalmology and Strabismus. 2017;21(5): 429-430.  https://doi.org/10.1016/j.jaapos.2017.06.016
  23. Zritel’nyye funktsii i ih korrektsiya u detey: Rukovodstvo dlya vrachey. Pod red. Avetisova S.E., Kaschenko T.P., Shamshinovoy A.M. M.: Medicina; 2005. (In Russ.).
  24. Di Giovanna F, Morreale Bubella D, Carità S, Morreale Bubella R, Lodato G. Retinal myelinated nerve fibers associated with macular pseudohole. Journal Francais de Ophtalmologie. 2008;31(3):295-298.  https://doi.org/10.1016/s0181-5512(08)74808-3
  25. Ramkumar HL, Verma R, Ferreyra HA, Robbins SL. Myelinated Retinal Nerve Fiber Layer (RNFL). International Ophthalmology Clinics. 2018;58(4): 147-156.  https://doi.org/10.1097/IIO.0000000000000239
  26. Duru I, Savides RP. Unilateral progressive myelinated retinal nerve fibres in an asymptomatic adult with optic nerve head drusen. Canadian Journal of Ophthalmology. 2018;53(4):136-138.  https://doi.org/10.1016/j.jcjo.2017.10.023
  27. Dean M, Kirschen D, Hubschman JP, Straatsma BR, Sarraf D, Francone A. Bilateral acquired progressive retinal nerve fiber layer myelination. Ophthalmic Surgery, Lasers and Imaging Retina. 2018;49(10):147-150.  https://doi.org/10.3928/23258160-20181002-18
  28. Corvi F, Querques G. Multimodal imaging of peripheral myelinated retinal nerve fiber layers without optic disk involvement. Journal Francais de Ophtalmologie. 2015;38(9):896-897.  https://doi.org/10.1016/j.jfo.2015.01.016
  29. Sheremet NL, Kharlap SI, Kiseleva TN, Budzinskaya MV, Kravchuk YeA. Optic disc drusen. Communication 1. The possibilities of diagnosis. Vestnik oftal’mologii. 2010;126(2):8-11. (In Russ.).
  30. Gharai S, Prakash G, Ashok Kumar D, Jacob S, Agarwal A, Arora V. Spectral domain optical coherence tomographic characteristics of unilateral peripapillary myelinated retinal nerve fibers involving the macula. Journal of Pediatric Ophthalmology and Strabismus. 2010;14(5):432-434.  https://doi.org/10.1016/j.jaapos.2010.05.010
  31. Sowka JW, Nadeau MJ. Regression of Myelinated Retinal Nerve Fibers in a Glaucomatous Eye. Optometry and Vision Science. 2013;90(7):218-220.  https://doi.org/10.1097/OPX.0b013e3182968b1a
  32. Katz SE, Weber PA. Photographic documentation of the loss of medullated nerve fibers of the retina in uncontrolled primary open angle glaucoma. Journal of Glaucoma. 1996;5(6):406-409. 
  33. Mashayekhi A, Shields CL, Shields JA. Disappearance of retinal myelinated nerve fibers after plaque radiotherapy for choroidal melanoma. Retina. 2003; 23(4):572-573.  https://doi.org/10.1097/00006982-200308000-00029
  34. Leys AM, Leys MJ, Hooymans JMM, Craandijk A, Malenfant M, van Germeersch D, Priem H, de Laey JJ. Myelinated nerve fibers and retinal vascular abnormalities. Retina. 1996;16(2):89-96.  https://doi.org/10.1097/00006982-199616020-00001
  35. Silvestri G, Sehmi K, Hamilton P. Retinal vascular abnormalities. A rare complication of myelinated nerve fibers? Retina. 1996;16(3):214-218. 
  36. Stoyukhina AS. Focal ossification as one of the reasons for erroneous diagnosis of chorioretinal lesions.Oftal’mologicheskie vedomosti. 2019;12(3):31-39. (In Russ.). https://doi.org/10.17816/OV15931
  37. Pusateri A, Margo CE. Intraocular Astrocytoma and Its Differential Diagnosis. Archives of Pathology and Laboratory Medicine. 2014;138:1250-1254. https://doi.org/10.5858/arpa.2013-0448-RS
  38. Bloom S, Mahl C. Photocoagulation for serous detachment of the macula secondary to retinal astrocytoma. Retina. 1991;11(4):416-422.  https://doi.org/10.1097/00006982-199110000-00009
  39. Shields JA, Shields CL. Glial tumors of the retina. The 2009 King Khaled Memorial Lecture. Saudi Journal of Ophthalmology. 2009;23(3-4):197-201.  https://doi.org/10.1016/j.sjopt.2009.10.003
  40. Myakoshina EB. Retinal astrocytic harmatoma: two clinical cases, visualization with the help spectral optical coherent tomography. Rossiyskaya pediatricheskaya oftal’mologiya. 2013;1:23-27. (In Russ.).
  41. Mennel S, Meyer CH, Eggarter F, Peter S. Autofluorescence and Angiographic Findings of Retinal Astrocytic Hamartomas in Tuberous Sclerosis. Ophthalmologica. 2005;219(6):350-356.  https://doi.org/10.1159/000088377
  42. Schwartz SG, Harbour JW. Multimodal Imaging of Astrocytic Hamartomas Associated With Tuberous Sclerosis. Ophthalmic Surgery, Lasers and Imaging Retina. 2017;48(9):756-758.  https://doi.org/10.3928/23258160-20170829-11
  43. Ophthalmooncologiya. Rukovodstvo dlya vracey. Pod red. Brovkinoy A.F. M.: Medicina; 2002. (In Russ.).
  44. Yung M, Iafe N, Sarraf D. Optical coherence tomography angiography of a retinal astrocytic hamartoma. Canadian Journal of Ophthalmology. 2016;51(2): 62-64.  https://doi.org/10.1016/j.jcjo.2015.11.005
  45. de Massougnes S, Malclès A, Souteyrand G, Massa H, Thumann G, Steffen H. Imagerie multimodale d’un hamartome astrocytaire rétinien. Journal Francais de Ophtalmologie. 2017;40(1):84-86.  https://doi.org/10.1016/j.jfo.2016.10.003
  46. Pichi F, Massaro D, Serafino M, Carrai P, Giuliari GP, Shields CL, Veronese C, Ciardella AP, Nucci P. Retinal Astrocytic Hamartoma: Optical Coherence Tomography Classification and Correlation with Tuberous Sclerosis Complex. Retina. 2015;36(6):1199-1208. https://doi.org/10.1097/IAE.0000000000000829
  47. Salazar-Quiñones L, Arcos-Villegas G, Valverde-Megías A, Flores-Moreno I, Méndez-Fernández R, Díaz-Valle D. Vitreous haemorrhage a rare manifestation of retinal astrocytic hamartoma: a paediatric case report. Archivos de la Sociedad Espanola de Oftalmologia. 2019;94(9):449-452.  https://doi.org/10.1016/j.oftal.2019.04.012
  48. De Juan E, Green WR, Gupta PK, Barañano EC. Vitreous seeding by retinal astrocytic hamartoma in a patient with tuberous sclerosis. Retina. 1984; 4(2):100-102.  https://doi.org/10.1097/00006982-198400420-00005
  49. Bypareddy R, Takkar B, Lohchab M, Azad SV, Chawla R. Association of Myelinated Retinal Nerve Fibers With Acquired Mulberry Retinal Astrocytoma: Coincidental or Relational? Ophthalmic Surgery, Lasers and Imaging Retina. 2017;48(5):441-442.  https://doi.org/10.3928/23258160-20170428-13
  50. Gass JDM. Cavernous hemangioma of the retina. A neuro-oculo-cutaneous syndrome. American Journal of Ophthalmology. 1971;71(4):799-814.  https://doi.org/10.1016/0002-9394(71)90245-5
  51. Lyu S, Zhang M, Wang RK, Gao Y, Zhang Q, Min X. Analysis of the characteristics of optical coherence tomography angiography for retinal cavernous hemangioma A case report. Medicine. 2018;97(7):e9940. https://doi.org/10.1097/MD.0000000000009940
  52. Yamaguchi K, Yamaguchi K, Tamai M. Cavernous hemangioma of the retina in a pediatric patient. Ophthalmologica. 1988;197(3):127-129.  https://doi.org/10.1159/000309932
  53. Gündüz K, Özbayrak N, Okka M, Okudan S, Zengin N. Cavernous hemangioma with cone dysfunction. Ophthalmologica. 1996;210(6):367-371.  https://doi.org/10.1159/000310749
  54. Hasanpour H, Ramezani A, Karimi S. Recurrent vitreous hemorrhage in a case of retinal cavernous hemangioma: A rare presentation. Journal of Ophthalmic and Vision Research. 2016;11(3):333-335.  https://doi.org/10.4103/2008-322X.188398
  55. Wang W, Chen L. Cavernous hemangioma of the retina a comprehensive review of the literature (1934-2015). Retina. 2017;37(4):611-621.  https://doi.org/10.1097/IAE.0000000000001374
  56. Rani PK, Peguda HK, Kaliki S, Chhablani J. Reverse fluorescein cap sign of cavernous haemangioma of optic nerve on OCT angiography. BMJ Case Reports. 2016;2016:bcr2016218176. https://doi.org/10.1136/bcr-2016-218176
  57. Singh E, Sen A. A case of retinal cavernous hemangioma analyzed with optical coherence tomography angiography. Indian Journal of Ophthalmology. 2019;67(4):561-563.  https://doi.org/10.4103/ijo.IJO_1478_18
  58. Pringle E, Chen S, Rubinstein A, Patel CK, Downes S. Optical coherence tomography in retinal cavernous haemangioma may explain the mechanism of vitreous haemorrhage. Eye (London, England). 2009;23(5):1242-1243. https://doi.org/10.1038/eye.2008.156
  59. Bloch E, Hakim J. Retinal Cavernous Hemangioma. Ophthalmology. 2015; 122(10):2037. https://doi.org/10.1016/j.ophtha.2015.07.006
  60. Shields JA, Eagle RC, Ewing MQ, Lally SE, Shields CL. Retinal cavernous hemangioma: Fifty-two years of clinical follow-up with clinicopathologic correlation. Retina. 2014;34(6):1253-1257. https://doi.org/10.1097/IAE.0000000000000232
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.