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Kurysheva N.I.

Medical Biological University of Innovations and Continuing Education of the Federal Biophysical Center named after A.I. Burnazyan;
Ophthalmological Center of the Federal Medical-Biological Agency of Russia;
Academy of Postgraduate Education of the Federal Research and Clinical Center of Specialized Types of Health Care and Medical Technology of the Federal Medical Biological Agency

Kim V.Yu.

Medical Biological University of Innovations and Continuing Education of the Federal Biophysical Center named after A.I. Burnazyan;
Ophthalmological Center of the Federal Medical-Biological Agency of Russia

Kim V.E.

Medical Biological University of Innovations and Continuing Education of the Federal Biophysical Center named after A.I. Burnazyan;
Ophthalmological Center of the Federal Medical-Biological Agency of Russia

Plieva Kh.M.

Medical Biological University of Innovations and Continuing Education of the Federal Biophysical Center named after A.I. Burnazyan;
Ophthalmological Center of the Federal Medical-Biological Agency of Russia

The role of the structure of the lamina cribrosa in the diagnosis and treatment of glaucoma. Structural and circulatory changes in the lamina cribrosa with aging and elevated intraocular pressure

Authors:

Kurysheva N.I., Kim V.Yu., Kim V.E., Plieva Kh.M.

More about the authors

Journal: Russian Annals of Ophthalmology. 2025;141(1): 76‑82

DOI: 10.17116/oftalma202514101176

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Table of contents

THE ROLE OF THE STRUCTURE OF THE LAMINA CRIBROSA IN THE DIAGNOSIS AND TREATMENT OF GLAUCOMA. STRUCTURAL AND CIRCULATORY CHANGES IN THE LAMINA CRIBROSA WITH AGING AND ELEVATED INTRAOCULAR PRESSURE
THE ROLE OF THE STRUCTURE OF THE LAMINA CRIBROSA IN THE DIAGNOSIS AND TREATMENT OF GLAUCOMA. STRUCTURAL AND CIRCULATORY CHANGES IN THE LAMINA CRIBROSA WITH AGING AND ELEVATED INTRAOCULAR PRESSURE

To cite this article:

Kurysheva NI, Kim VYu, Kim VE, Plieva KhM. The role of the structure of the lamina cribrosa in the diagnosis and treatment of glaucoma. Structural and circulatory changes in the lamina cribrosa with aging and elevated intraocular pressure. Russian Annals of Ophthalmology. 2025;141(1):76‑82. (In Russ.)
https://doi.org/10.17116/oftalma202514101176

Подписка 2026 Вестник офтальмологии (Russian Annals of Ophthalmology)
 
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Abstract:

The earliest damage in glaucoma starts in the posterior pole of the eye, where the axons of retinal ganglion cells, that form the optic nerve fibers, and retinal vessels pass through the connective tissue network called the lamina cribrosa (LC). Modern diagnostic techniques, such as optical coherence tomography (OCT), enable the visualization of the LC and the assessment of blood flow within it, providing new opportunities for the diagnosis of glaucoma. This review highlights the anatomy and vascularization of the LC, along with the latest research findings obtained via OCT. The article details age-related changes in the LC and the impact of intraocular pressure (IOP) changes on its properties. A novel parameter, the lamina cribrosa curvature index (LCCI), reflecting LC deformation, has been shown to be the most important biomarker of glaucomatous damage.

Keywords:

primary open-angle glaucoma
lamina cribrosa
ocular blood flow
optical coherence tomography
choroid
choriocapillaris blood flow

Authors:

Kurysheva N.I.

Medical Biological University of Innovations and Continuing Education of the Federal Biophysical Center named after A.I. Burnazyan;
Ophthalmological Center of the Federal Medical-Biological Agency of Russia;
Academy of Postgraduate Education of the Federal Research and Clinical Center of Specialized Types of Health Care and Medical Technology of the Federal Medical Biological Agency

Kim V.Yu.

Medical Biological University of Innovations and Continuing Education of the Federal Biophysical Center named after A.I. Burnazyan;
Ophthalmological Center of the Federal Medical-Biological Agency of Russia

Kim V.E.

Medical Biological University of Innovations and Continuing Education of the Federal Biophysical Center named after A.I. Burnazyan;
Ophthalmological Center of the Federal Medical-Biological Agency of Russia

Plieva Kh.M.

Medical Biological University of Innovations and Continuing Education of the Federal Biophysical Center named after A.I. Burnazyan;
Ophthalmological Center of the Federal Medical-Biological Agency of Russia

Received:

13.06.2023

Accepted:

19.07.2023

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