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Tezikov Yu.V.

Samara State Medical University

Lipatov I.S.

Samara State Medical University

Yakusheva A.O.

Samara State Medical University

Novel coronavirus infection and pregnancy: features of the course of gestation and the possibility of predicting the progression of COVID-19 severity in pregnant women

Authors:

Tezikov Yu.V., Lipatov I.S., Yakusheva A.O.

More about the authors

Journal: Russian Bulletin of Obstetrician-Gynecologist. 2023;23(1): 30‑38

DOI: 10.17116/rosakush20232301130

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To cite this article:

Tezikov YuV, Lipatov IS, Yakusheva AO. Novel coronavirus infection and pregnancy: features of the course of gestation and the possibility of predicting the progression of COVID-19 severity in pregnant women. Russian Bulletin of Obstetrician-Gynecologist. 2023;23(1):30‑38. (In Russ.)
https://doi.org/10.17116/rosakush20232301130

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The authors analyzed the literature data on the possibility of timely diagnosis and prognosis of COVID-19 progression and development of life-threatening complications during gestation. Pregnant women are at high risk for a severe course of the disease, which is inherent in the prerequisites of gestational adaptation mechanisms. This review presents various aspects of COVID-19 and pregnancy, ranging from the etiopathogenesis and clinical features of the course of the disease in pregnant women to highly informative laboratory methods for predicting the severity of COVID-19. The studies presented demonstrate the scientific and practical interest in developing and implementing pathogenetically valid markers to stratify pregnant women at risk for COVID-19 progression and adverse gestational, perinatal, and somatic outcomes. The current knowledge and practice are insufficient for their large-scale application to effectively address the challenges of timely diagnosis of COVID-19 severity and the prognosis of life-threatening complications, prolonged course of disease, or postconceptional syndrome, which is essential to maintain quality of life, fully develop the biological system of mother and newborn, and preserve reproductive potential.

Keywords:

pregnancy
COVID-19
new coronavirus infection
severity prediction
early diagnosis
severity of COVID-19 course

Authors:

Tezikov Yu.V.

Samara State Medical University

Lipatov I.S.

Samara State Medical University

Yakusheva A.O.

Samara State Medical University

Received:

28.03.2022

Accepted:

26.04.2022

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