«Role and place of tezepelumab in the treatment of rhinosinusitis with nasal polyps». Resolution of the Expert Council

Kim IA, Svistushkin VM, Nosulya EV, et al. «Role and place of tezepelumab in the treatment of rhinosinusitis with nasal polyps». Resolution of the Expert Council. Russian Rhinology. 2025;33(4):90‑92. (In Russ.)
https://doi.org/10.17116/rosrino20253304190

Подписка 2026 Российская ринология (Russian Rhinology)

Использование инфографики авторами научных работ

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Abstract:

The article presents a resolution of the Council of Experts: «Role and place of tezepelumab in the treatment of rhinosinusitis with nasal polyps», accepted following the discussion of the results of the WAYPOINT study, the expert consensus of EPOS/EUFOREA.

Keywords:

rhinosinusitis with nasal polyps

WAYPOINT

EPOS/EUFOREA

tezepelumab

biological therapy

Authors:

Kim I.A.

National Medical Research Center of Otorhinolaryngology

ORCID: 0000-0003-1078-6388

Svistushkin V.M.

I.M. Sechenov First Moscow State Medical University (Sechenov University)

SPIN RSCI: 9040-5720
Scopus AuthorID: 6602512088
ORCID: 0000-0001-7414-1293

Nosulya E.V.

Research Clinical Institute of Otorhinolaryngology named after. L.I. Sverzhevsky

ORCID: 0000-0002-3897-8384

Emelyanov A.V.

North-Western State Medical University named after I.I. Mechnikov

ORCID: 0000-0002-8574-6869

Egorov V.I.

Moscow Regional Scientific Research Clinical Institute named after M. F. Vladimirsky

ORCID: 0000-0002-8825-5096

Ryazantsev S.V.

Saint Petersburg Research Institute of Ear, Throat, Nose and Speech

ORCID: 0000-0003-1710-3092

Karpischenko S.A.

Pavlov First Saint Petersburg State Medical University

ORCID: 0000-0003-1124-1937

Pelishenko T.G.

Clinical Hospital No. 1 (Volynskaya) of the Administrative Directorate of the President of the Russian Federation

ORCID: 0000-0001-6597-2167

Khanova F.M.

National Medical Research Center of Otorhinolaryngology

ORCID: 0000-0001-9362-9139

Received:

23.10.2025

Accepted:

30.10.2025

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References:

Clinical guidelines «Polyposis rhinosinusitis» 2024. National Medical Association of Otolaryngologists. Approved by the Scientific and Practical Council of the Ministry of Health of the Russian FederationAccessed October 14, 2025. (In Russ.). https://cr.minzdrav.gov.ru/preview-cr/890_1
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He H, Liu C, Ni L, Zhang Y, Zhou X. The Role of Thymic Stromal Lymphopoietin in the Pathogenesis of Inflammatory Airway Diseases. Int J Mol Sci. 2024;25(11):5972. https://doi.org/10.3390/ijms25115972
Pyo JS, Kim SJ. Relationship between histologic changes and inflammatory markers in chronic rhinosinusitis. Int J Clin Exp Pathol. 2021 Apr 15; 14(4):501-507.
Lipworth BJ, Han JK, Desrosiers M, Hopkins C, Lee SE, Mullol J, Pfaar O, Li T, Chen C, Almqvist G, Margolis MK, McLaren J, Jagadeesh S, MacKay J, Megally A, Hellqvist Å, Mankad VS, Bahadori L, Ponnarambil SS; WAYPOINT Study Investigators. Tezepelumab in Adults with Severe Chronic Rhinosinusitis with Nasal Polyps. N Engl J Med. 2025 Mar 27;392(12): 1178-1188. https://doi.org/10.1056/NEJMoa2414482