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Shteiner M.L.

Samara City Hospital No. 4;
Samara State Medical University

Zhestkov A.V.

Samara Medical University REAVIZ

Makova E.V.

Samara City Hospital No. 4;
Samara Medical University REAVIZ

Biktagirov Yu.I.

Samara State Medical University

Korymasov E.A.

Samara State Medical University

Krivoshchekov E.P.

Samara State Medical University

Cough-syncope syndrome in a patient with severe exacerbation of COPD. (A clinical case)

Authors:

Shteiner M.L., Zhestkov A.V., Makova E.V., Biktagirov Yu.I., Korymasov E.A., Krivoshchekov E.P.

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Journal: Journal of Respiratory Medicine. 2025;1(4): 59‑62

DOI: 10.17116/respmed2025104159

Read: 836 times

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Table of contents

COUGH-SYNCOPE SYNDROME IN A PATIENT WITH SEVERE EXACERBATION OF COPD. (A CLINICAL CASE)
COUGH-SYNCOPE SYNDROME IN A PATIENT WITH SEVERE EXACERBATION OF COPD. (A CLINICAL CASE)

To cite this article:

Shteiner ML, Zhestkov AV, Makova EV, Biktagirov YuI, Korymasov EA, Krivoshchekov EP. Cough-syncope syndrome in a patient with severe exacerbation of COPD. (A clinical case). Journal of Respiratory Medicine. 2025;1(4):59‑62. (In Russ.)
https://doi.org/10.17116/respmed2025104159

Подписка 2026 Респираторная медицина (Journal of Respiratory Medicine)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

In a patient with a severe exacerbation of chronic obstructive pulmonary disease, there was a concomitant manifestation of cough-syncope syndrome with episodes of loss of consciousness at the height of cough attacks. The patient’s severe condition, progressive respiratory failure against the background of massive obstruction of the lower respiratory tract by bronchial secretions, forced to use bronchological aid. Instead of standard local anesthesia, deep sedation under the cover of glucocorticosteroids was used to suppress the cough reflex. Bronchological intervention was carried out in full and resolved pronounced bronchial obstruction. The performed bronchological interventions against the background of intensive systemic therapy allowed to stop the severe exacerbation of the disease and to level out the manifestations of cough-fainting syndrome.

Keywords:

cough-fainting syndrome
chronic obstructive pulmonary disease
severe exacerbation of chronic obstructive pulmonary disease
bronchological manual

Authors:

Shteiner M.L.

Samara City Hospital No. 4;
Samara State Medical University

Zhestkov A.V.

Samara Medical University REAVIZ

Makova E.V.

Samara City Hospital No. 4;
Samara Medical University REAVIZ

Biktagirov Yu.I.

Samara State Medical University

Korymasov E.A.

Samara State Medical University

Krivoshchekov E.P.

Samara State Medical University

Received:

15.10.2025

Accepted:

13.11.2025

Close metadata

References:

  1. Global Initiative for Chronic Obstructive Lung Disease (GOLD). 2023. Accessed September 14, 2025. https://goldcopd.org/2023-gold-report-2/
  2. MacLeod M, Papi A, Contoli M, Beghé B, Celli BR, Wedzicha JA, Fabbri LM Chronic obstructive pulmonary disease exacerbation fundamentals: Diagnosis, treatment, prevention and disease impact. Respirology. 2021;26(6):532-551.  https://doi.org/10.1111/resp.14041
  3. Ko FW, Chan KP, Hui DS, Goddard JR, Shaw JG, Reid DW, Yang IA. Acute exacerbation of COPD. Respirology. 2016;21(7):1152-1165. https://doi.org/10.1111/resp.12780
  4. Deshmukh A, Schuller D. Cough syncope in a patient with severe chronic obstructive pulmonary disease. Respiratory Medicine CME. 2008;1:120-122.  https://doi.org/10.1016/j.rmedc.2008.01.004
  5. Skaletskaya V, Simonike Yu, Moskovchuk A. Tracheobronchial dyskinesia in patients with severe COPD. Tuberkuloz i sotsial’no znachimyye zabolevaniya. 2013;2.83-84. (In Russ.).
  6. Brignole M, Moya A, de Lange FJ, Deharo JC, Elliott PM, Fanciulli A, Fedorowski A, Furlan R, Kenny RA, Martín A, Probst V, Reed MJ, Rice CP, Sutton R, Ungar A, van Dijk JG. ESC Scientific Document Group. 2018 ESC Guidelines for the diagnosis and management of syncope. European heart journal. 2018;39(21):1883-1948. https://doi.org/10.1093/eurheartj/ehy-037
  7. Duplyakov DV, Golovina GA, Osina II, Tukhbatova AA. Cough syncope. Vestnik aritmologii. 2012;69:69-73. (In Russ.).
  8. Dicpinigaitis PV, Lim L, Farmakidis C. Cough syncope. Respir Med. 2014;108(2):244-251.  https://doi.org/10.1016/j.rmed.2013.10.020
  9. Abdelmalak BB, Gildea TR, Doyle DJ. Anesthesia for bronchoscopy. Curr. Pharm. Des. 2012;18(38):6314-6324. https://doi.org/10.2174/138161212803832290
  10. Goudra BG, Singh PM, Borle A, Farid N, Harris K. Anesthesia for Advanced Bronchoscopic Procedures: State of the Art Review. Lung. 2015;193(4):453-465.  https://doi.org/10.1007/s00408-015-9733-7
  11. Shteiner ML. An approach to local anesthesia during flexible bronchoscopy. Izvestiia vysshikh uchebnykh zavedenii. Povolzhskii region. Meditsinskie nauki. 2020;3(55):32-40. (In Russ.). https://doi.org/10.21685/2072-3032-2020-3-3
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