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Kaibysheva V.O.

National Medical Research Center for Therapy and Preventive Medicine;
Pirogov Russian National Research Medical University

Tykhonov S.V.

North-Western State Medical University named after I.I. Mechnikov

Kashin S.V.

National Medical Research Center for Therapy and Preventive Medicine;
Regional Clinical Oncological Hospital

Kuvaev R.O.

Pirogov Russian National Research Medical University;
Regional Clinical Oncological Hospital

Kraynova E.A.

Moscow City Oncology Hospital No. 62

Baculina N.V.

North-Western State Medical University named after I.I. Mechnikov

Fedorov E.D.

Pirogov Russian National Research Medical University

Drapkina O.M.

National Medical Research Center for Therapy and Preventive Medicine

Algorithm of autoimmune gastritis diagnosis and treatment

Authors:

Kaibysheva V.O., Tykhonov S.V., Kashin S.V., Kuvaev R.O., Kraynova E.A., Baculina N.V., Fedorov E.D., Drapkina O.M.

More about the authors

Journal: Russian Journal of Preventive Medicine. 2024;27(9): 101‑110

DOI: 10.17116/profmed202427091101

Views: 4013

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To cite this article:

Kaibysheva VO, Tykhonov SV, Kashin SV, et al. . Algorithm of autoimmune gastritis diagnosis and treatment. Russian Journal of Preventive Medicine. 2024;27(9):101‑110. (In Russ.)
https://doi.org/10.17116/profmed202427091101

Подписка 2025 (Russian Journal of Preventive Medicine)
 
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Autoimmune gastritis (AIG) is an unknown disease that results in the destruction of the oxyntic mucosa, mucosal atrophy and metaplasia of the gastric corpus and fundus, leading to impaired production of hydrochloric acid and intrinsic factor, and associated with the increased risk of iron deficiency and B12-deficiency anemia and gastric neoplasia. Early diagnosis of autoimmune gastritis is complicated due to the abcence of specific symptoms and endoscopic changes at the non-atrophic stage of the disease. The earliest and the most common clinical manifestation of AIG is anemia due to iron and vitamin B12 deficiency, but the most danger complication of AIG is the development of gastric neoplasia. This review presents an algorithm for the diagnosis and treatment of AIG based on a current knowledge about of the disease pathogenesis, and the results of clinical trials that are consistent with the principles of evidence-based medicine.

Keywords:

gastritis
autoimmune gastritis
anacid gastritis
metaplasia
atrophy
neuroendocrine tumor
vitamin B12
iron-deficient anemia

Authors:

Kaibysheva V.O.

National Medical Research Center for Therapy and Preventive Medicine;
Pirogov Russian National Research Medical University

Tykhonov S.V.

North-Western State Medical University named after I.I. Mechnikov

Kashin S.V.

National Medical Research Center for Therapy and Preventive Medicine;
Regional Clinical Oncological Hospital

Kuvaev R.O.

Pirogov Russian National Research Medical University;
Regional Clinical Oncological Hospital

Kraynova E.A.

Moscow City Oncology Hospital No. 62

Baculina N.V.

North-Western State Medical University named after I.I. Mechnikov

Fedorov E.D.

Pirogov Russian National Research Medical University

Drapkina O.M.

National Medical Research Center for Therapy and Preventive Medicine

Received:

10.08.2024

Accepted:

16.08.2024

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