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Suponeva N.A.

Research Center of Neurology

Arestova A.S.

Research Center of Neurology

Neurological complications resulting of nitrous oxide intoxication

Authors:

Suponeva N.A., Arestova A.S.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(12): 41‑46

DOI: 10.17116/jnevro202412412141

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Table of contents

NEUROLOGICAL COMPLICATIONS RESULTING OF NITROUS OXIDE INTOXICATION
NEUROLOGICAL COMPLICATIONS RESULTING OF NITROUS OXIDE INTOXICATION

To cite this article:

Suponeva NA, Arestova AS. Neurological complications resulting of nitrous oxide intoxication. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(12):41‑46. (In Russ.)
https://doi.org/10.17116/jnevro202412412141

Подписка 2025-2 (S.S. Korsakov Journal of Neurology and Psychiatry)
 
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Nitrous oxide (NO) intoxication is a common consequence of its inhalation with recreational purpose, which is prevalent among young people. The most severe result of such an entertainment is development of myelopolyneuropathy with polyneuropathy as the most common presentation, which may start acutely or subacutely. The underlying cause of neurological complications of NO intoxication is deficit of B12 vitamin, however its laboratory confirmation may be challenging. The key aspect of treatment of neurological symptoms in such patients is prescription of adequate dosage of B12 for a long period of time. In this paper we present the clinical case, which demonstrates challenges of vitamin B12 deficiency verification and advantages of oral cyanocobalamin prescription.

Keywords:

vitamin B12
nitrous oxide
polyneuropathy

Authors:

Suponeva N.A.

Research Center of Neurology

Arestova A.S.

Research Center of Neurology

Received:

03.10.2024

Accepted:

26.11.2024

List of references:

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