Evaluating the efficacy of the Kyoto classification of gastritis in diagnosing Helicobacter pylori infection

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MATERIAL AND METHODS

A retrospective case-control study involving 329 patients (206 women and 123 men) with a median age of 49 years (range 17—85 years) who underwent examination from 2020 to 2024. High-resolution white-light endoscopy and narrow-band imaging modes was used. H. pylori infection was diagnosed using histological examination and a rapid urease test. Statistical analysis included logistic regression and ROC analysis.

RESULTS

Statistically significant endoscopic features of infected mucosa included diffuse hyperemia (OR=255; 95% CI 91.3—937.3), enlarged folds (OR=10.7; 95% CI 3.190—35.906), granularity (OR=17.3; 95% CI 2.3—131.8), and mucosal edema (OR=15.1; 95% CI 8.663—26.445). Non-infected mucosa was characterized by regular arrangement of collecting venules (OR=0.018; 95% CI 0.006—0.060) and their recurrence (OR=0.074; 95% CI 0.035—0.156). The predictive model showed a sensitivity of 92.9% and specificity of 93.2%.

CONCLUSION

The Kyoto classification of gastritis has proven to be a simple and effective tool for endoscopic diagnosis of H. pylori-associated gastritis. The study results offer new opportunities for clinical practice, facilitating early diagnosis and reducing gastric cancer incidence.

Keywords:

Helicobacter pylori

gastritis

endoscopy

Kyoto classification

atrophy

Authors:

Korzheva I.Yu.

Russian Medical Academy for Continuous Professional Education;
Botkin Moscow Multidisciplinary Scientific and Clinical Center

ORCID: 0000-0002-5984-5660

Laktyun’kina E.N.

Russian Medical Academy for Continuous Professional Education;
Veresaev Moscow City Clinical Hospital

ORCID: 0000-0002-5920-5380

Kozyr’ L.V.

Pirogov Russian National Research Medical University

ORCID: 0009-0002-5254-5873

Syzrantsev A.Yu.

Botkin Moscow Multidisciplinary Scientific and Clinical Center

ORCID: 0009-0001-8153-4412

Received:

09.10.2024

Accepted:

19.11.2024

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